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Related papers: Optimal Vaccine Allocation for Pandemic Stabilizat…

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During the COVID-19 pandemic, there were over three million infections in Los Angeles County (LAC). To facilitate distribution when vaccines first became available, LAC set up six mega-sites for dispensing a large number of vaccines to the…

Optimization and Control · Mathematics 2025-02-27 Suyanpeng Zhang , Sze-chuan Suen , Han Yu , Maged Dessouky , Fernando Ordonez

This paper studies an optimal control problem for a class of SIR epidemic models, in scenarios in which the infected population is constrained to be lower than a critical threshold imposed by the ICU (intensive care unit) capacity. The…

Optimization and Control · Mathematics 2024-12-31 Matteo Della Rossa , Lorenzo Freddi , Dan Goreac

Mass vaccination offers a promising exit strategy for the COVID-19 pandemic. However, as vaccination progresses, demands to lift restrictions increase, despite most of the population remaining susceptible. Using our age-stratified SEIRD-ICU…

Populations and Evolution · Quantitative Biology 2021-09-07 Simon Bauer , Sebastian Contreras , Jonas Dehning , Matthias Linden , Emil Iftekhar , Sebastian B. Mohr , Álvaro Olivera-Nappa , Viola Priesemann

Because a fast vaccination rollout against coronavirus disease 2019 (COVID-19) is critical to restore daily life and avoid virus mutations, it is tempting to have a relaxed vaccination-administration management system. However, a robust…

Quantitative Methods · Quantitative Biology 2022-03-17 Jorge Medina , Roberto Rojas-Cessa , Vatcharapan Umpaichitra

The effectiveness of vaccination highly depends on the choice of individuals to vaccinate, even if the same number of individuals are vaccinated. Vaccinating individuals with high centrality measures such as betweenness centrality (BC) and…

Physics and Society · Physics 2021-12-30 Bukyoung Jhun

The COVID-19 pandemic has posed a policy making crisis where efforts to slow down or end the pandemic conflict with economic priorities. This paper provides mathematical analysis of optimal disease control policies with idealized…

Optimization and Control · Mathematics 2021-02-16 Aaron Z. Palmer , Zelda B. Zabinsky , Shan Liu

We develop a mathematical model for transferring the vaccine BNT162b2 based on the heat diffusion equation. Then, we apply optimal control theory to the proposed generalized SEIR model. We introduce vaccination for the susceptible…

Optimization and Control · Mathematics 2022-04-22 Mohamed Abdelaziz Zaitri , Mohand Ouamer Bibi , Delfim F. M. Torres

Given limited supply of approved vaccines and constrained medical resources, design of a vaccination strategy to control a pandemic is an economic problem. We use time-series and panel methods with real-world country-level data to estimate…

General Economics · Economics 2022-01-19 Dongwoo Kim , Young Jun Lee

Effective strategies of vaccine prioritization are essential to mitigate the impacts of severe infectious diseases. We investigate the role of infection fatality ratio (IFR) and social contact matrices on vaccination prioritization using a…

Populations and Evolution · Quantitative Biology 2023-10-04 Arthur Schulenburg , Wesley Cota , Guilherme S. Costa , Silvio C. Ferreira

In this study, we explore the dynamic interplay between the timing of vaccination campaigns and the trajectory of disease spread in a population. Through comprehensive data analysis and modeling, we have uncovered a counter-intuitive…

Physics and Society · Physics 2024-12-06 Piergiorgio Castioni , Sergio Gòmez , Clara Granell , Alex Arenas

This study assesses the impact of COVID-19 vaccines through an epidemiological model that quantifies their role in pandemic control. We analyze an SIR-based model incorporating vaccination effects and calculate the basic reproduction…

Dynamical Systems · Mathematics 2025-07-29 Tesfalem Abate Tegegn , Yibeltal Adane Terefe

The COVID-19 pandemic highlighted significant challenges in the allocation of vital healthcare resources. Existing epidemiological models, specifically compartmental models, aimed to predict the spread of the COVID-19 virus and its impact…

Physics and Society · Physics 2024-03-14 Hieu Bui , Sandra Eksioglu , Ruben Proano

This research is about COVID-19, which is a contagious virus that reached many countries, including Lebanon. Monitoring the outbreak, researchers have been involved in introducing COVID-19 targeting vaccines. Already facing financial and…

Applications · Statistics 2023-12-22 Sarkis Der Wartanian , Baydaa Al Ayoubi

Game theory has been an effective tool in the control of disease spread and in suggesting optimal policies at both individual and area levels. In this paper, we propose a multi-region SEIR model based on stochastic differential game theory,…

Optimization and Control · Mathematics 2021-03-10 Yao Xuan , Robert Balkin , Jiequn Han , Ruimeng Hu , Hector D. Ceniceros

This paper presents a study on a compartmental epidemic model for COVID-19, examining the stability of its equilibrium points upon the introduction of vaccination as a strategy to mitigate the spread of the disease. Initially, the SIQR…

Numerical Analysis · Mathematics 2024-05-29 Leonardo R. S. Rodrigues , Felipe Gabrielli

Background: By the beginning of December 2020, some vaccines against COVID-19 already presented efficacy and security, which qualify them to be used in mass vaccination campaigns. Thus, setting up strategies of vaccination became crucial to…

Populations and Evolution · Quantitative Biology 2021-02-25 Vinicius V. L. Albani , Jennifer Loria , Eduardo Massad , Jorge P. Zubelli

We consider the bi-objective problem of allocating doses of a (perfect) vaccine to an infinite-dimensional metapopulation in order to minimize simultaneously the vaccination cost and the effective reproduction number $R_e$, which is defined…

Optimization and Control · Mathematics 2022-12-19 Jean-François Delmas , Dylan Dronnier , Pierre-André Zitt

The mitigation of an infectious disease spreading has recently gained considerable attention from the research community. It may be obtained by adopting sanitary measurements social rules, together with an extensive vaccination campaign.…

Social and Information Networks · Computer Science 2022-02-17 Francesco Petrizzelli , Pietro Hiram Guzzi , Tommaso Mazza

This research introduces a new approach utilizing optimal control theory (OCT) to assess the Social Optimum (SO) of a vaccination game, navigating the intricate considerations of cost, availability, and distribution policies. By integrating…

Optimization and Control · Mathematics 2025-01-14 Md. Mamun-Ur-Rashid Khan , Jun Tanimoto

We study how a fraction of a population should be vaccinated to most efficiently top epidemics. We argue that only local information (about the neighborhood of specific vertices) is usable in practice, and hence we consider only local…

Populations and Evolution · Quantitative Biology 2007-05-23 Petter Holme
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