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Related papers: Optimal Vaccine Allocation for Pandemic Stabilizat…

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In this paper, we present a decision support framework for optimizing multiple aspects of vaccine distribution across a multitier cold chain network. We propose two multi-period optimization formulations within this framework: first to…

Physics and Society · Physics 2022-01-12 Shanmukhi Sripada , Ayush Jain , Prasanna Ramamoorthy , Varun Ramamohan

Since the recent introduction of several viable vaccines for SARS-CoV-2, vaccination uptake has become the key factor that will determine our success in containing the COVID-19 pandemic. We argue that game theory and social network models…

A major focus of debate about rationing guidelines for COVID-19 vaccines is whether and how to prioritize access for minority populations that have been particularly affected by the pandemic, and been the subject of historical and…

General Economics · Economics 2020-09-08 Parag A. Pathak , Harald Schmidt , Adam Solomon , Edwin Song , Tayfun Sönmez , M. Utku Ünver

Vaccinations against viruses have always been the need of the hour since long past. However, it is hard to efficiently distribute the vaccines (on time) to all the corners of a country, especially during a pandemic. Considering the vastness…

Machine Learning · Computer Science 2022-08-03 Jayeeta Mondal , Jeet Dutta , Hrishav Bakul Barua

With the present highly infectious dominant SARS-CoV-2 strain of B1.1.529 or Omicron spreading around the globe, there is concern that the COVID-19 pandemic will not end soon and that it will be a race against time until a more contagious…

Populations and Evolution · Quantitative Biology 2022-04-26 Chottiwatt Jittprasong

With the invention of the COVID-19 vaccine, shipping and distributing are crucial in controlling the pandemic. In this paper, we build a mean-field variational problem in a spatial domain, which controls the propagation of pandemic by the…

Optimization and Control · Mathematics 2022-07-12 Wonjun Lee , Siting Liu , Wuchen Li , Stanley Osher

During decades, mathematical models have been used to predict the behavior of physical and biologic systems, and to define strategies aiming the minimization of the effects regarding different types of diseases. In the present days, the…

Populations and Evolution · Quantitative Biology 2020-04-22 Gustavo Barbosa Libotte , Fran Sérgio Lobato , Gustavo Mendes Platt , Antônio José da Silva Neto

We introduce an immunization method where the percentage of required vaccinations for immunity are close to the optimal value of a targeted immunization scheme of highest degree nodes. Our strategy retains the advantage of being purely…

Physics and Society · Physics 2009-11-13 Lazaros K. Gallos , Fredrik Liljeros , Panos Argyrakis , Armin Bunde , Shlomo Havlin

We propose a new method to immunize populations or computer networks against epidemics which is more efficient than any method considered before. The novelty of our method resides in the way of determining the immunization targets. First we…

Physics and Society · Physics 2015-06-03 Christian M. Schneider , Tamara Mihaljev , Hans J. Herrmann

We consider a SIR model with vaccination strategy on a sparse configuration model random graph. We show the convergence of the system when the number of nodes grows and characterize the scaling limits. Then, we prove the existence of…

Probability · Mathematics 2021-02-26 Emanuel Javier Ferreyra , Matthieu Jonckheere , Juan Pablo Pinasco

The pursuit of strategies that minimize the number of individuals needing vaccination to control an outbreak is a well-established area of study in mathematical epidemiology. However, for certain diseases, public policy tends to prioritize…

Populations and Evolution · Quantitative Biology 2026-01-30 J. Orestes Cerdeira , Fabio A. C. C. Chalub , Matheus Hansen

In this article, we construct an age-structured model for COVID-19 with vaccination and analyze it from multiple perspectives. We derive the unique disease-free equilibrium point and the basic reproduction number $ \mathscr{R}_0 $, then we…

Populations and Evolution · Quantitative Biology 2024-07-09 Ruiyang Zhou , Fengying Wei

In this paper, we study the problem of minimizing the spread of a viral epidemic when immunization takes a non-negligible amount of time to take into effect. Specifically, our problem is to determine which set of nodes to be vaccinated when…

Social and Information Networks · Computer Science 2023-07-14 Shiju Li , Xin Huang , Chul-Ho Lee , Do Young Eun

SIR models, also with age structure, can be used to describe the evolution of an infective disease. A vaccination campaign influences this dynamics immunizing part of the susceptible individuals, essentially turning them into recovered…

Analysis of PDEs · Mathematics 2019-10-17 Rinaldo M. Colombo , Mauro Garavello

We study in a general mathematical framework the optimal allocation of vaccine in an heterogeneous population. We cast the problem of optimal vaccination as a bi-objective minimization problem min(C($\eta$),L($\eta$)), where C and L stand…

Optimization and Control · Mathematics 2025-03-21 Jean-François Delmas , Dylan Dronnier , Pierre-André Zitt

Besides maintaining health precautions, vaccination has been the only prevention from SARS-CoV-2, though no clinically proved 100% effective vaccine has been developed till date. At this stage, to withhold the debris of this pandemic,…

Quarantine of those individuals who are suspected of being infected is one of the intervention measures to contain the spread of an infectious disease. We propose an age structured SEQIR (S-Susceptible, E-Exposed, Q-Quarantine, I-Infected,…

Analysis of PDEs · Mathematics 2020-12-21 Manoj Kumar , Syed Abbas

A COVID-19 vaccine is our best bet for mitigating the ongoing onslaught of the pandemic. However, vaccine is also expected to be a limited resource. An optimal allocation strategy, especially in countries with access inequities and temporal…

We aim to design a fairness-aware allocation approach to maximize the geographical diversity and avoid unfairness in the sense of demographic disparity. During the development of this work, the COVID-19 pandemic is still spreading in the…

Optimization and Control · Mathematics 2026-05-12 Hadis Anahideh , Lulu Kang , Nazanin Nezami

Efficient testing and vaccination protocols are critical aspects of epidemic management. To study the optimal allocation of limited testing and vaccination resources in a heterogeneous contact network of interacting susceptible, recovered,…

Populations and Evolution · Quantitative Biology 2026-05-12 Mingtao Xia , Lucas Böttcher , Tom Chou