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With the approval of vaccines for the coronavirus disease by many countries worldwide, most developed nations have begun, and developing nations are gearing up for the vaccination process. This has created an urgent need to provide a…

Computers and Society · Computer Science 2021-02-09 Mahzabeen Emu , Dhivya Chandrasekaran , Vijay Mago , Salimur Choudhury

During various stages of the COVID-19 pandemic, countries implemented diverse vaccine management approaches, influenced by variations in infrastructure and socio-economic conditions. This article provides a comprehensive overview of…

Optimization and Control · Mathematics 2024-05-27 Shibshankar Dey , Ali Kaan Kurbanzade , Esma S. Gel , Joseph Mihaljevic , Sanjay Mehrotra

This research investigates a multi-product, multi-echelon, and multi-period vaccine supply chain network model under uncertainty and quality inspection errors. The objective function seeks optimizing the total cost of the supply chain.…

Optimization and Control · Mathematics 2024-05-07 Bouchenine Abderrahmen , Almaraj Ismail

In this study, a vaccine supply chain model is developed considering the humanitarian aspects under uncertain conditions in Iran. There are three main components to supply the required vaccines for vaccination centers that can be designed…

Optimization and Control · Mathematics 2022-08-30 Behnam Malmir , Christopher W. Zobel

Vaccines play a crucial role in the prevention and control of infectious diseases. However, the vaccine supply chain faces numerous challenges that hinder its efficiency. To address these challenges and enhance public health outcomes, many…

Theoretical Economics · Economics 2025-10-07 Ran Gu , Enhui Ding , Shigui Ma

Purpose: Only few companies were able to produce vaccine again COVID-19. Thus, one producer supplied it to many countries. The distribution was not effective. Some countries overstocked the vaccine while other countries were not able to buy…

Physics and Society · Physics 2024-08-20 Béla Vizvári , Gergely Kovács

Epidemic risk assessment poses inherent challenges, with traditional approaches often failing to balance health outcomes and economic constraints. This paper presents a data-driven decision support tool that models epidemiological dynamics…

Applications · Statistics 2025-11-24 Chang Zhai , Ping Chen , Zhuo Jin , David Pitt

The optimal allocation of vaccines to population subgroups over time is a challenging health care management problem. In the context of a pandemic, the interaction between vaccination policies adopted by multiple agents and the cooperation…

Optimization and Control · Mathematics 2021-09-22 David Rey , Ahmed W Hammad , Meead Saberi

With the continuous rise of the COVID-19 cases worldwide, it is imperative to ensure that all those vulnerable countries lacking vaccine resources can receive sufficient support to contain the risks. COVAX is such an initiative operated by…

Computational Engineering, Finance, and Science · Computer Science 2022-01-20 Navpreet Kaur , Jason Hughes , Juntao Chen

Timely and effective decision-making is critical during epidemics to reduce preventable infections and deaths. This demands integrated models that jointly capture disease dynamics, vaccine distribution, regional disparities, and behavioral…

Social and Information Networks · Computer Science 2025-11-26 Kimiya Jozani , Nihal A. Sageer , Hode Eldardiry , Sait Tunc , Esra Buyuktahtakin Toy

This study presents a mathematical model for optimal vaccination strategies in interconnected metropolitan areas, considering commuting patterns. It is a compartmental model with a vaccination rate for each city, acting as a control…

Populations and Evolution · Quantitative Biology 2024-04-29 Lucas Machado Moschen , María Soledad Aronna

Millions of young people are not immunized in low- and middle-income (LMI) countries because of low vaccine availability resulting from inefficiencies in cold supply chains. We create supply chain network design and distribution models to…

Applications · Statistics 2020-06-11 Zahra Azadi , Sandra D. Eksioglu , H. Neil Geismar

The outbreak of COVID-19 led to a record-breaking race to develop a vaccine. However, the limited vaccine capacity creates another massive challenge: how to distribute vaccines to mitigate the near-end impact of the pandemic? In the United…

Populations and Evolution · Quantitative Biology 2021-07-20 Dimitris Bertsimas , Vassilis Digalakis , Alexander Jacquillat , Michael Lingzhi Li , Alessandro Previero

As observed during the COVID-19 pandemic, high-income countries, such as the U.S., may exhibit vaccine nationalism during a pandemic: stockpiling doses of vaccine for their own citizens and being reluctant to distribute doses of the vaccine…

Populations and Evolution · Quantitative Biology 2024-08-21 Abraham Holleran , Susan E. Martonosi , Michael Veatch

Effective and efficient scheduling of vaccine distribution can significantly impact vaccine uptake, which is critical to controlling the spread of infectious diseases. Ineffective scheduling can lead to waste, delays, and low vaccine…

Optimization and Control · Mathematics 2024-03-13 Nicholas Uhorchak , Ruben A. Proano , Sandra Eksioglu , Fatih Cengil , Burak Eksioglu

This study explores the vaccine prioritization strategy to reduce the overall burden of the pandemic when the supply is limited. Existing methods conduct macro-level or simplified micro-level vaccine distribution by assuming the homogeneous…

Populations and Evolution · Quantitative Biology 2023-05-10 Lu Ling , Washim Uddin Mondal , Satish V , Ukkusuri

Multi-model prediction efforts in infectious disease modeling and climate modeling involve multiple teams independently producing projections under various scenarios. Often these scenarios are produced by the presence and absence of a…

Methodology · Statistics 2022-08-11 Yuanhao Lu , Ajitesh Srivastava

In this paper, we study the optimal control for an SEIR model adapted to the vaccination strategy of susceptible individuals. There are factors associated with a vaccination campaign that make this strategy not only a public health issue…

Optimization and Control · Mathematics 2024-11-08 Nelson L. Santos Junior , João A. M. Gondim

We develop a model of infection spread that takes into account the existence of a vulnerable group as well as the variability of the social relations of individuals. We develop a compartmentalized power-law model, with power-law connections…

Physics and Society · Physics 2020-10-13 Simone Santini

Since early 2020, the world has been dealing with a raging pandemic outbreak: COVID-19. A year later, vaccines have become accessible, but in limited quantities, so that governments needed to devise a strategy to decide which part of the…

Populations and Evolution · Quantitative Biology 2022-04-13 Sander Tonkens , Paul de Klaver , Mauro Salazar
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