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We introduce Delay Pruning, a simple yet powerful technique to regularize dynamic Boltzmann machines (DyBM). The recently introduced DyBM provides a particularly structured Boltzmann machine, as a generative model of a multi-dimensional…

Machine Learning · Computer Science 2016-10-07 Sakyasingha Dasgupta , Takayuki Yoshizumi , Takayuki Osogami

Marketing decisions reflect the interaction of latent consumer heterogeneity, time-varying internal states, and explicit interventions, a structure that current prediction- and language-oriented models do not capture in a unified manner. We…

Artificial Intelligence · Computer Science 2026-05-11 Junichiro Niimi

Restricted Boltzmann machines (RBMs) are endowed with the universal power of modeling (binary) joint distributions. Meanwhile, as a result of their confining network structure, training RBMs confronts less difficulties (compared with more…

Machine Learning · Computer Science 2015-10-22 Sai Zhang

Estimation of Distribution Algorithms (EDAs) require flexible probability models that can be efficiently learned and sampled. Restricted Boltzmann Machines (RBMs) are generative neural networks with these desired properties. We integrate an…

Neural and Evolutionary Computing · Computer Science 2014-12-01 Malte Probst , Franz Rothlauf , Jörn Grahl

We developed an adaptive structure learning method of Restricted Boltzmann Machine (RBM) which can generate/annihilate neurons by self-organizing learning method according to input patterns. Moreover, the adaptive Deep Belief Network (DBN)…

Neural and Evolutionary Computing · Computer Science 2018-07-12 Shin Kamada , Takumi Ichimura

Deep reinforcement learning is used in various domains, but usually under the assumption that the environment has stationary conditions like transitions and state distributions. When this assumption is not met, performance suffers. For this…

Machine Learning · Computer Science 2024-05-24 Zihe Liu , Jie Lu , Guangquan Zhang , Junyu Xuan

Deep Learning has the hierarchical network architecture to represent the complicated features of input patterns. Such architecture is well known to represent higher learning capability compared with some conventional models if the best set…

Neural and Evolutionary Computing · Computer Science 2018-07-12 Takumi Ichimura , Shin Kamada

Datasets in the real world are often complex and to some degree hierarchical, with groups and sub-groups of data sharing common characteristics at different levels of abstraction. Understanding and uncovering the hidden structure of these…

Machine Learning · Computer Science 2023-07-10 Aurélien Decelle , Lorenzo Rosset , Beatriz Seoane

This paper presents a novel Robust Deep Appearance Models to learn the non-linear correlation between shape and texture of face images. In this approach, two crucial components of face images, i.e. shape and texture, are represented by Deep…

Computer Vision and Pattern Recognition · Computer Science 2016-07-05 Kha Gia Quach , Chi Nhan Duong , Khoa Luu , Tien D. Bui

The Restricted Boltzmann Machine (RBM), an important tool used in machine learning in particular for unsupervized learning tasks, is investigated from the perspective of its spectral properties. Starting from empirical observations, we…

Disordered Systems and Neural Networks · Physics 2018-01-17 Aurélien Decelle , Giancarlo Fissore , Cyril Furtlehner

Restricted Boltzmann Machines (RBMs) offer a versatile architecture for unsupervised machine learning that can in principle approximate any target probability distribution with arbitrary accuracy. However, the RBM model is usually not…

Machine Learning · Computer Science 2022-09-27 Lennart Dabelow , Masahito Ueda

Dense Associative Memory (DAM) models have been attracting renewed attention since they were shown to be robust to adversarial examples and closely related to cutting edge machine learning paradigms, such as the attention mechanism and…

Machine Learning · Computer Science 2026-01-27 Robin Thériault , Daniele Tantari

Predicting drug-target binding affinity (DTA) is essential for identifying potential therapeutic candidates in drug discovery. However, most existing models rely heavily on static protein structures, often overlooking the dynamic nature of…

Robotics · Computer Science 2025-05-20 Dan Luo , Jinyu Zhou , Le Xu , Sisi Yuan , Xuan Lin

Computing equilibrium states in condensed-matter many-body systems, such as solvated proteins, is a long-standing challenge. Lacking methods for generating statistically independent equilibrium samples in "one shot", vast computational…

Machine Learning · Statistics 2019-07-15 Frank Noé , Simon Olsson , Jonas Köhler , Hao Wu

Boltzmann machines (BMs) are powerful energy-based generative models, but their heavy training cost has largely confined practical use to Restricted BMs (RBMs) trained with an efficient learning method called contrastive divergence. More…

Machine Learning · Computer Science 2025-12-03 Kentaro Kubo , Hayato Goto

The moments of spatial probabilistic systems are often given by an infinite hierarchy of coupled differential equations. Moment closure methods are used to approximate a subset of low order moments by terminating the hierarchy at some order…

Machine Learning · Computer Science 2019-05-30 Oliver K. Ernst , Tom Bartol , Terrence Sejnowski , Eric Mjolsness

Accurate prediction of protein-protein binding affinity is vital for understanding molecular interactions and designing therapeutics. We adapt Boltz-2, a state-of-the-art structure-based protein-ligand affinity predictor, for…

Machine Learning · Computer Science 2025-12-09 James King , Lewis Cornwall , Andrei Cristian Nica , James Day , Aaron Sim , Neil Dalchau , Lilly Wollman , Joshua Meyers

The restricted Boltzmann machine is a network of stochastic units with undirected interactions between pairs of visible and hidden units. This model was popularized as a building block of deep learning architectures and has continued to…

Machine Learning · Computer Science 2018-06-20 Guido Montufar

A restricted Boltzmann machine (RBM) is a generative neural-network model with many novel applications such as collaborative filtering and acoustic modeling. An RBM lacks the capacity to retain memory, making it inappropriate for dynamic…

Machine Learning · Statistics 2018-05-01 Jefferson Hernandez , Andres G. Abad

Composed of amino acid chains that influence how they fold and thus dictating their function and features, proteins are a class of macromolecules that play a central role in major biological processes and are required for the structure,…

Quantitative Methods · Quantitative Biology 2022-07-15 Aaron Wang