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Epidemiological processes are studied within a recently proposed hierarchical network model using the susceptible-infected-refractory dynamics of an epidemic. Within the network model, a population may be characterized by $H$ independent…

Disordered Systems and Neural Networks · Physics 2008-06-24 Dafang Zheng , P. M. Hui , Steffen Trimper , Bo Zheng

This is work in progress. We make it accessible hoping that people might find the idea useful. We propose a discrete, recursive 5-compartment model for the spread of epidemics, which we call {\em SEPIR-model}. Under mild assumptions which…

Populations and Evolution · Quantitative Biology 2020-09-02 Matthias Kreck , Erhard Scholz

The distribution of the ratios of consecutive eigenvalue spacings of random matrices has emerged as an important tool to study spectral properties of many-body systems. This article numerically investigates the eigenvalue ratios…

Disordered Systems and Neural Networks · Physics 2022-07-13 Ankit Mishra , Tanu Raghav , Sarika Jalan

Increasing rates of global trade and travel, as well as changing climatic patterns, have led to more frequent outbreaks of plant disease epidemics worldwide. Mathematical modelling is a key tool in predicting where and how these new threats…

Populations and Evolution · Quantitative Biology 2019-11-28 Frédéric Fabre , Jérôme Coville , Nik J. Cunniffe

This paper deals with the problem of estimating variables in nonlinear models for the spread of disease and its application to the COVID-19 epidemic. First unconstrained methods are revisited and they are shown to correspond to the…

Optimization and Control · Mathematics 2020-08-20 Mauricio C. de Oliveira

Epidemic modeling is an essential tool to understand the spread of the novel coronavirus and ultimately assist in disease prevention, policymaking, and resource allocation. In this article, we establish a state of the art interface between…

Applications · Statistics 2020-12-17 Li Wang , Guannan Wang , Lei Gao , Xinyi Li , Shan Yu , Myungjin Kim , Yueying Wang , Zhiling Gu

Infectious disease transmission in human populations has a complex two-way interaction with changes in host behaviour. It is increasingly recognised that incorporating adaptive behavioural change into epidemic models is important for…

Populations and Evolution · Quantitative Biology 2026-04-14 Michael J. Plank , Matt Ryan , Lloyd Chapman , Roslyn I. Hickson , Thomas House , Emma McBryde , James M. McCaw

Bayesian inference methods are useful in infectious diseases modeling due to their capability to propagate uncertainty, manage sparse data, incorporate latent structures, and address high-dimensional parameter spaces. However, parameter…

Methodology · Statistics 2025-04-29 Xiahui Li , Fergus Chadwick , Ben Swallow

In the face of an infectious disease, a key epidemiological measure is the basic reproduction number, which quantifies the average secondary infections caused by a single case in a susceptible population. In practice, the effective…

Physics and Society · Physics 2025-03-11 Xin-Jian Xu , Song-Jie He , Li-Jie Zhang

In this paper, we study a reaction-diffusion vector-host epidemic model. We define the basic reproduction number $R_0$ and show that $R_0$ is a threshold parameter: if $R_0\le 1$ the disease free steady state is globally stable; if $R_0>1$…

Analysis of PDEs · Mathematics 2018-12-05 Pierre Magal , G. F. Webb , Yixiang Wu

Recent years have seen a large amount of interest in epidemics on networks as a way of representing the complex structure of contacts capable of spreading infections through the modern human population. The configuration model is a popular…

Populations and Evolution · Quantitative Biology 2017-01-23 Frank Ball , Thomas House

We propose a novel multi-scale modeling framework for infectious disease spreading, borrowing ideas and modeling tools from the so-called Refractory Density (RD) approach. We introduce a microscopic model that describes the probability of…

Populations and Evolution · Quantitative Biology 2025-03-24 Anton Chizhov , Laurent Pujo-Menjouet , Tilo Schwalger , Mattia Sensi

We present a stochastic model for two successive SIR (Susceptible, Infectious, Recovered) epidemics in the same network structured population. Individuals infected during the first epidemic might have (partial) immunity for the second one.…

Populations and Evolution · Quantitative Biology 2024-10-29 Frank Ball , Abid Ali Lashari , David Sirl , Pieter Trapman

Recent evidences show that individuals who recovered from COVID-19 can be reinfected. However, this phenomenon has rarely been studied using mathematical models. In this paper, we propose a SEIRE epidemic model to describe the spread of the…

Populations and Evolution · Quantitative Biology 2022-05-17 Shaoli Wang , Tengfei Wang , Ya-nen Qi , Fei Xu

The dynamics of many epidemic models for infectious diseases that spread in a single host population demonstrate a threshold phenomenon. If the basic reproduction number R0 is below unity, the disease-free equilibrium P0 is globally stable…

Dynamical Systems · Mathematics 2020-07-16 Abdelkader Intissar

We develop a new structured compartmental model for the coevolutionary dynamics between susceptible and infectious individuals in heterogeneous SI epidemiological systems. In this model, the susceptible compartment is structured by a…

Populations and Evolution · Quantitative Biology 2024-10-10 Tommaso Lorenzi , Elisa Paparelli , Andrea Tosin

Time-to-event models are commonly used to study associations between risk factors and disease outcomes in the setting of electronic health records (EHR). In recent years, focus has intensified on social determinants of health, highlighting…

Applications · Statistics 2025-11-26 Yueming Shen , Christian Pean , David Dunson , Samuel Berchuck

We consider two approaches to study the spread of infectious diseases within a spatially structured population distributed in social clusters. According whether we consider only the population of infected individuals or both populations of…

Probability · Mathematics 2007-10-30 Lamia Belhadji

Network-based models of epidemic spread have become increasingly popular in recent decades. Despite a rich foundation of such models, few low-dimensional systems for modeling SIS-type diseases have been proposed that manage to capture the…

Dynamical Systems · Mathematics 2021-01-01 Carl Corcoran , Alan Hastings

The importance of spatial networks in the spread of an epidemic is an essential aspect in modeling the dynamics of an infectious disease. Additionally, any realistic data-driven model must take into account the large uncertainty in the…

Populations and Evolution · Quantitative Biology 2022-01-17 Giulia Bertaglia , Lorenzo Pareschi