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Morphology of mitochondria plays critical roles in mediating their physiological functions. Accurate segmentation of mitochondria from 3D electron microscopy (EM) images is essential to quantitative characterization of their morphology at…

Computer Vision and Pattern Recognition · Computer Science 2022-06-16 Yunpeng Xiao , Youpeng Zhao , Ge Yang

Recent studies suggest a potential link between the physical structure of mitochondria and neurodegenerative diseases. With advances in Electron Microscopy techniques, it has become possible to visualize the boundary and internal membrane…

Computer Vision and Pattern Recognition · Computer Science 2025-02-11 Faris Serdar Taşel , Efe Çiftci

While deep learning models have achieved state-of-the-art accuracies for many prediction tasks, understanding these models remains a challenge. Despite the recent interest in developing visual tools to help users interpret deep learning…

Human-Computer Interaction · Computer Science 2017-08-10 Minsuk Kahng , Pierre Y. Andrews , Aditya Kalro , Duen Horng Chau

Mitochondria segmentation in electron microscopy images is essential in neuroscience. However, due to the image degradation during the imaging process, the large variety of mitochondrial structures, as well as the presence of noise,…

Computer Vision and Pattern Recognition · Computer Science 2021-09-28 Zhili Li , Xuejin Chen , Jie Zhao , Zhiwei Xiong

Mitochondrial diseases are currently untreatable due to our limited understanding of their pathology. We study the expression of various mitochondrial proteins in skeletal myofibres (SM) in order to discover processes involved in…

Machine Learning · Computer Science 2022-11-01 Atif Khan , Conor Lawless , Amy E Vincent , Satish Pilla , Sushanth Ramesh , A. Stephen McGough

Recently, deep learning has been advancing the state of the art in artificial intelligence to a new level, and humans rely on artificial intelligence techniques more than ever. However, even with such unprecedented advancements, the lack of…

Human-Computer Interaction · Computer Science 2018-04-10 Jaegul Choo , Shixia Liu

Metasurfaces, sub-wavelength artificial structures, can control light's amplitude, phase, and polar ization, enabling applications in efficient imaging, holograms, and sensing. Recent years, AI has witnessed remarkable progress and spurred…

Optics · Physics 2025-04-22 Jiahao Yan , Jilong Yi , Churong Ma , Yanjun Bao , Qin Chen , Baojun Li

In medical imaging, most of the image registration methods implicitly assume a one-to-one correspondence between the source and target images (i.e., diffeomorphism). However, this is not necessarily the case when dealing with pathological…

Image and Video Processing · Electrical Eng. & Systems 2022-02-03 Matthis Maillard , Anton François , Joan Glaunès , Isabelle Bloch , Pietro Gori

Intelligent biological systems are characterized by their embodiment in a complex environment and the intimate interplay between their nervous systems and the nonlinear mechanical properties of their bodies. This coordination, in which the…

Machine Learning · Computer Science 2023-02-02 Deniz Oktay , Mehran Mirramezani , Eder Medina , Ryan P. Adams

Mitochondrial networks exhibit a variety of complex behaviors, including coordinated cell-wide oscillations of energy states as well as a phase transition (depolarization) in response to oxidative stress. Since functional and structural…

Training neural networks is difficult to interpret, particularly for newcomers. We introduce NeuroViz, an interactive visualization tool that supports real-time exploration of fully connected neural network training. Users can configure…

Machine Learning · Computer Science 2026-05-26 Tanvi Sharma , Reza Rawassizadeh

Rapid developments in machine vision have led to advances in a variety of industries, from medical image analysis to autonomous systems. These achievements, however, typically necessitate digital neural networks with heavy computational…

Computer Vision and Pattern Recognition · Computer Science 2023-06-14 Hanyu Zheng , Quan Liu , Ivan I. Kravchenko , Xiaomeng Zhang , Yuankai Huo , Jason G. Valentine

We present a method for visualising the response of a deep neural network to a specific input. For image data for instance our method will highlight areas that provide evidence in favor of, and against choosing a certain class. The method…

Computer Vision and Pattern Recognition · Computer Science 2017-06-13 Luisa M. Zintgraf , Taco S. Cohen , Max Welling

The fields of artificial intelligence and neuroscience have a long history of fertile bi-directional interactions. On the one hand, important inspiration for the development of artificial intelligence systems has come from the study of…

Neurons and Cognition · Quantitative Biology 2019-11-21 Eilif B. Muller , Philippe Beaudoin

In many real-world scientific problems, generating ground truth (GT) for supervised learning is almost impossible. The causes include limitations imposed by scientific instrument, physical phenomenon itself, or the complexity of modeling.…

Image and Video Processing · Electrical Eng. & Systems 2020-08-31 Arif Ahmed Sekh , Ida S. Opstad , Rohit Agarwal , Asa Birna Birgisdottir , Truls Myrmel , Balpreet Singh Ahluwalia , Krishna Agarwal , Dilip K. Prasad

The uninformative ordering of artificial neurons in Deep Neural Networks complicates visualizing activations in deeper layers. This is one reason why the internal structure of such models is very unintuitive. In neuroscience, activity of…

Audio and Speech Processing · Electrical Eng. & Systems 2019-12-10 Andreas Krug , Sebastian Stober

Although deep encoder-decoder networks have achieved astonishing performance for mitochondria segmentation from electron microscopy (EM) images, they still produce coarse segmentations with lots of discontinuities and false positives.…

Computer Vision and Pattern Recognition · Computer Science 2020-01-30 Zhimin Yuan , Jiajin Yi , Zhengrong Luo , Zhongdao Jia , Jialin Peng

Whether it be in a man-made machine or a biological system, form and function are often directly related. In the latter, however, this particular relationship is often unclear due to the intricate nature of biology. Here we developed a…

Neurons and Cognition · Quantitative Biology 2020-05-27 Fernanda L. Ribeiro , Steffen Bollmann , Alexander M. Puckett

To analyze this characteristic of vulnerability, we developed an automated deep learning method for detecting microvessels in intravascular optical coherence tomography (IVOCT) images. A total of 8,403 IVOCT image frames from 85 lesions and…

Deep image prior (DIP) is a recently proposed technique for solving imaging inverse problems by fitting the reconstructed images to the output of an untrained convolutional neural network. Unlike pretrained feedforward neural networks, the…

Computer Vision and Pattern Recognition · Computer Science 2022-09-20 Kevin Zhang , Mingyang Xie , Maharshi Gor , Yi-Ting Chen , Yvonne Zhou , Christopher A. Metzler
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