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Motivation: With the development of droplet based systems, massive single cell transcriptome data has become available, which enables analysis of cellular and molecular processes at single cell resolution and is instrumental to…

Machine Learning · Computer Science 2018-12-27 Tiehang Duan , José P. Pinto , Xiaohui Xie

We address the problem of un-supervised soft-clustering called micro-clustering. The aim of the problem is to enumerate all groups composed of records strongly related to each other, while standard clustering methods separate records at…

Data Structures and Algorithms · Computer Science 2016-06-07 Takeaki Uno , Hiroki Maegawa , Takanobu Nakahara , Yukinobu Hamuro , Ryo Yoshinaka , Makoto Tatsuta

High-order clustering aims to classify objects in multiway datasets that are prevalent in various fields such as bioinformatics, recommendation systems, and social network analysis. Such data are often sparse and high-dimensional, posing…

Statistics Theory · Mathematics 2025-12-05 Ian Välimaa , Lasse Leskelä

In many real-world problems, we are dealing with collections of high-dimensional data, such as images, videos, text and web documents, DNA microarray data, and more. Often, high-dimensional data lie close to low-dimensional structures…

Computer Vision and Pattern Recognition · Computer Science 2013-02-06 Ehsan Elhamifar , Rene Vidal

In electronic health records (EHR) analysis, clustering patients according to patterns in their data is crucial for uncovering new subtypes of diseases. Existing medical literature often relies on classical hypothesis testing methods to…

Methodology · Statistics 2024-05-07 Zihan Zhu , Xin Gai , Anru R. Zhang

In this paper we present a method for the unsupervised clustering of high-dimensional binary data, with a special focus on electronic healthcare records. We present a robust and efficient heuristic to face this problem using tensor…

Machine Learning · Statistics 2017-08-31 Matteo Ruffini , Ricard Gavaldà , Esther Limón

Clustering data objects into homogeneous groups is one of the most important tasks in data mining. Spectral clustering is arguably one of the most important algorithms for clustering, as it is appealing for its theoretical soundness and is…

Machine Learning · Statistics 2024-03-12 Dylan Soemitro , Jeova Farias Sales Rocha Neto

Nowadays, many machine learning procedures are available on the shelve and may be used easily to calibrate predictive models on supervised data. However, when the input data consists of more than one unknown cluster, and when different…

Applications · Statistics 2019-11-18 Aurélie Fisher , Mathilde Mougeot , Sothea Has

When scholars suspect units are dependent on each other within clusters but independent of each other across clusters, they employ cluster-robust standard errors (CRSEs). Nevertheless, what to cluster over is sometimes unknown. For…

Methodology · Statistics 2025-11-12 Kentaro Fukumoto

Clustering algorithms are one of the main analytical methods to detect patterns in unlabeled data. Existing clustering methods typically treat samples in a dataset as points in a metric space and compute distances to group together similar…

Machine Learning · Computer Science 2021-10-12 Tarek Naous , Srinjay Sarkar , Abubakar Abid , James Zou

We present a novel probabilistic clustering model for objects that are represented via pairwise distances and observed at different time points. The proposed method utilizes the information given by adjacent time points to find the…

Machine Learning · Computer Science 2015-04-16 Julia E. Vogt , Marius Kloft , Stefan Stark , Sudhir S. Raman , Sandhya Prabhakaran , Volker Roth , Gunnar Rätsch

In longitudinal data analysis, observation points of repeated measurements over time often vary among subjects except in well-designed experimental studies. Additionally, measurements for each subject are typically obtained at only a few…

Methodology · Statistics 2024-11-14 Michio Yamamoto , Yoshikazu Terada

We study the problem of applying spectral clustering to cluster multi-scale data, which is data whose clusters are of various sizes and densities. Traditional spectral clustering techniques discover clusters by processing a similarity…

Machine Learning · Computer Science 2020-06-09 Xiang Li , Ben Kao , Caihua Shan , Dawei Yin , Martin Ester

Although many successful ensemble clustering approaches have been developed in recent years, there are still two limitations to most of the existing approaches. First, they mostly overlook the issue of uncertain links, which may mislead the…

Machine Learning · Statistics 2016-06-06 Dong Huang , Jian-Huang Lai , Chang-Dong Wang

Background and Objective: Variables collected over time, or longitudinally, such as biologic measurements in electronic health records data, are not simple to summarize with a single time-point, and thus can be more holistically…

Finite mixture models that allow for a broad range of potentially non-elliptical cluster distributions is an emerging methodological field. Such methods allow for the shape of the clusters to match the natural heterogeneity of the data,…

Spectral clustering is a powerful method for finding structure in a dataset through the eigenvectors of a similarity matrix. It often outperforms traditional clustering algorithms such as $k$-means when the structure of the individual…

Numerical Analysis · Mathematics 2019-04-26 Paola Favati , Grazia Lotti , Ornella Menchi , Francesco Romani

We propose a node clustering method for time-varying graphs based on the assumption that the cluster labels are changed smoothly over time. Clustering is one of the fundamental tasks in many science and engineering fields including signal…

Machine Learning · Computer Science 2023-05-12 Katsuki Fukumoto , Koki Yamada , Yuichi Tanaka , Hoi-To Wai

In this paper, we introduce a novel and interpretable methodology to cluster subjects suffering from cancer, based on features extracted from their biopsies. Contrary to existing approaches, we propose here to capture complex patterns in…

Quantitative Methods · Quantitative Biology 2020-07-07 Yassine El Ouahidi , Matis Feller , Matthieu Talagas , Bastien Pasdeloup

Curating large-scale fully annotated datasets is expensive, laborious, and cumbersome, especially for medical images. Several methods have been proposed in the literature that make use of weak annotations in the form of scribbles. However,…

Computer Vision and Pattern Recognition · Computer Science 2025-04-01 Ke Zhang , Vishal M. Patel
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