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Mixtures of matrix Gaussian distributions provide a probabilistic framework for clustering continuous matrix-variate data, which are becoming increasingly prevalent in various fields. Despite its widespread adoption and successful…

Computation · Statistics 2023-07-21 Andrea Cappozzo , Alessandro Casa , Michael Fop

In heterogeneous disorders like Parkinson's disease (PD), differentiating the affected population into subgroups plays a key role in future research. Discovering subgroups can lead to improved treatments through more powerful enrichment of…

Methodology · Statistics 2023-08-08 Elliot Burghardt , Daniel Sewell , Joseph Cavanaugh

Medical data often exhibit characteristics that make cluster analysis particularly challenging, such as missing values, outliers, and cluster features like skewness. Typically, such data would need to be preprocessed -- by cleaning outliers…

Methodology · Statistics 2025-12-16 Jason Pillay , Cristina Tortora , Antonio Punzo , Andriette Bekker

Interpreting large volumes of high-dimensional, unlabeled data in a manner that is comprehensible to humans remains a significant challenge across various domains. In unsupervised healthcare data analysis, interpreting clustered data can…

Machine Learning · Computer Science 2025-06-17 Shehroz S. Khan , Ali Abedi , Charlene H. Chu

Clustering is a fundamental data mining tool that aims to divide data into groups of similar items. Generally, intuition about clustering reflects the ideal case -- exact data sets endowed with flawless dissimilarity between individual…

Machine Learning · Computer Science 2016-01-25 Margareta Ackerman , Jarrod Moore

We use a cluster ensemble to determine the number of clusters, k, in a group of data. A consensus similarity matrix is formed from the ensemble using multiple algorithms and several values for k. A random walk is induced on the graph…

Machine Learning · Statistics 2014-08-06 Shaina Race , Carl Meyer , Kevin Valakuzhy

Currently, data-driven discovery in biological sciences resides in finding segmentation strategies in multivariate data that produce sensible descriptions of the data. Clustering is but one of several approaches and sometimes falls short…

Quantitative Methods · Quantitative Biology 2022-08-12 Richard Tjörnhammar

We study the problem of clustering sequences of unlabeled point sets taken from a common metric space. Such scenarios arise naturally in applications where a system or process is observed in distinct time intervals, such as biological…

Data Structures and Algorithms · Computer Science 2017-10-17 Tamal K. Dey , Alfred Rossi , Anastasios Sidiropoulos

Diabetes is one of the most prevalent diseases worldwide, characterized by persistently high blood sugar levels, capable of damaging various internal organs and systems. Diabetes patients require routine check-ups, resulting in a time…

Machine Learning · Computer Science 2025-05-13 Onthada Preedasawakul , Nathakhun Wiroonsri

Improving the future of healthcare starts by better understanding the current actual practices in hospital settings. This motivates the objective of discovering typical care pathways from patient data. Revealing typical care pathways can be…

Machine Learning · Computer Science 2024-12-20 Thomas Guyet , Pierre Pinson , Enoal Gesny

As single-cell gene expression data analysis continues to grow, the need for reliable clustering methods has become increasingly important. The prevalence of heuristic means for method choice could lead to inaccurate reports if…

Quantitative Methods · Quantitative Biology 2026-05-19 Owen Visser , Somnath Datta

Spectral clustering is one of the most widely used techniques for extracting the underlying global structure of a data set. Compressed sensing and matrix completion have emerged as prevailing methods for efficiently recovering sparse and…

Numerical Analysis · Mathematics 2010-11-05 Blake Hunter , Thomas Strohmer

Identifying the number $K$ of clusters in a dataset is one of the most difficult problems in clustering analysis. A choice of $K$ that correctly characterizes the features of the data is essential for building meaningful clusters. In this…

Methodology · Statistics 2019-05-06 Adriano Zanin Zambom , Julian A. Collazos , Ronaldo Dias

Functional data analysis deals with data recorded densely over time (or any other continuum) with one or more observed curves per subject. Conceptually, functional data are continuously defined, but in practice, they are usually observed at…

Methodology · Statistics 2023-01-20 Chengqian Xian , Camila de Souza , John Jewell , Ronaldo Dias

In this paper, we compare and analyze clustering methods with missing data in health behavior research. In particular, we propose and analyze the use of compressive sensing's matrix completion along with spectral clustering to cluster…

Numerical Analysis · Mathematics 2014-04-24 Ran Zhao , Deanna Needell , Christopher Johansen , Jerry L. Grenard

Patient similarity analysis is important in health care applications. It takes patient information such as their electronic medical records and genetic data as input and computes the pairwise similarity between patients. Procedures of…

Machine Learning · Computer Science 2020-12-04 Leyu Dai , He Zhu , Dianbo Liu

There is a keen interest in characterizing variation in the microbiome across cancer patients, given increasing evidence of its important role in determining treatment outcomes. Here our goal is to discover subgroups of patients with…

Applications · Statistics 2022-12-06 Yushu Shi , Liangliang Zhang , Kim-Anh Do , Robert Jenq , Christine Peterson

Most classification methods are based on the assumption that data conforms to a stationary distribution. The machine learning domain currently suffers from a lack of classification techniques that are able to detect the occurrence of a…

Machine Learning · Statistics 2012-01-05 Alzennyr Da Silva , Yves Lechevallier , Fabrice Rossi , Francisco De A. T. De Carvahlo

Clustering is a widely used technique in data mining applications for discovering patterns in underlying data. Most traditional clustering algorithms are limited to handling datasets that contain either numeric or categorical attributes.…

Artificial Intelligence · Computer Science 2007-05-23 Zengyou He , Xiaofei Xu , Shengchun Deng

High-dimensional clustering analysis is a challenging problem in statistics and machine learning, with broad applications such as the analysis of microarray data and RNA-seq data. In this paper, we propose a new clustering procedure called…

Methodology · Statistics 2022-10-31 Tianqi Liu , Yu Lu , Biqing Zhu , Hongyu Zhao