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From a fresh data science perspective, this thesis discusses the prediction of coronary artery disease based on genetic variations at the DNA base pair level, called Single-Nucleotide Polymorphisms (SNPs), collected from the Ontario Heart…

Machine Learning · Computer Science 2014-02-04 Hubert Haoyang Duan

Many countries are now experiencing the third wave of the COVID-19 pandemic straining the healthcare resources with an acute shortage of hospital beds and ventilators for the critically ill patients. This situation is especially worse in…

Accurate prediction of cardiovascular diseases remains imperative for early diagnosis and intervention, necessitating robust and precise predictive models. Recently, there has been a growing interest in multi-modal learning for uncovering…

Computer Vision and Pattern Recognition · Computer Science 2024-11-12 Francesco Girlanda , Olga Demler , Bjoern Menze , Neda Davoudi

Kidneys are the filter of the human body. About 10% of the global population is thought to be affected by Chronic Kidney Disease (CKD), which causes kidney function to decline. To protect in danger patients from additional kidney damage,…

The aim is to create a method for accurately estimating the duration of post-cancer treatment, particularly focused on chemotherapy, to optimize patient care and recovery. This initiative seeks to improve the effectiveness of cancer…

Computers and Society · Computer Science 2025-04-24 Joyee Chakraborty , Mazahrul Islam Tohin , Danbir Rashid , Tanjil Ahmed Tanmoy , Md. Jehadul Islam Mony

Machine Learning (ML) algorithms are generally designed for scenarios in which all data is stored in one data center, where the training is performed. However, in many applications, e.g., in the healthcare domain, the training data is…

Machine Learning · Computer Science 2024-09-16 Amin Aminifar , Matin Shokri , Amir Aminifar

Stakeholders make various types of decisions with respect to requirements, design, management, and so on during the software development life cycle. Nevertheless, these decisions are typically not well documented and classified due to…

Software Engineering · Computer Science 2021-05-05 Liming Fu , Peng Liang , Xueying Li , Chen Yang

Objective: Machine learning (ML) predictive models are often developed without considering downstream value trade-offs and clinical interpretability. This paper introduces a cost-aware prediction (CAP) framework that combines cost-benefit…

Machine Learning · Computer Science 2025-11-20 Yinan Yu , Falk Dippel , Christina E. Lundberg , Martin Lindgren , Annika Rosengren , Martin Adiels , Helen Sjöland

According to the American Diabetes Association(ADA), 30.3 million people in the United States have diabetes, but only 7.2 million may be undiagnosed and unaware of their condition. Type 2 diabetes is usually diagnosed for most patients…

Machine Learning · Computer Science 2019-10-22 Ramya Akula , Ni Nguyen , Ivan Garibay

Objective: Worldwide, heart failure (HF) is a major cause of morbidity and mortality and one of the leading causes of hospitalization. Early detection of HF symptoms and pro-active management may reduce adverse events. Approach:…

Signal Processing · Electrical Eng. & Systems 2021-04-06 Ayse S. Cakmak , Samuel Densen , Gabriel Najarro , Pratik Rout , Christopher J. Rozell , Omer T. Inan , Amit J. Shah , Gari D. Clifford

Predicting the probability of default (PD) of prospective loans is a critical objective for financial institutions. In recent years, machine learning (ML) algorithms have achieved remarkable success across a wide variety of prediction…

Risk Management · Quantitative Finance 2025-06-25 Adrian Iulian Cristescu , Matteo Giordano

Mutagenicity is a concern due to its association with genetic mutations which can result in a variety of negative consequences, including the development of cancer. Earlier identification of mutagenic compounds in the drug development…

Machine Learning · Computer Science 2024-09-06 Tanya Liyaqat , Tanvir Ahmad , Mohammad Kashif , Chandni Saxena

Matching is an appealing way to design observational studies because it mimics the data structure produced by stratified randomized trials, pairing treated individuals with similar controls. After matching, inference is often conducted…

Methodology · Statistics 2024-03-05 Samuel D. Pimentel , Ruoqi Yu

Accurate predictions of when a component will fail are crucial when planning maintenance, and by modeling the distribution of these failure times, survival models have shown to be particularly useful in this context. The presented…

Machine Learning · Computer Science 2024-03-28 Olov Holmer , Mattias Krysander , Erik Frisk

Current clinical practice guidelines for managing Coronary Artery Disease (CAD) account for general cardiovascular risk factors. However, they do not present a framework that considers personalized patient-specific characteristics. Using…

Machine Learning · Statistics 2019-10-21 Dimitris Bertsimas , Agni Orfanoudaki , Rory B. Weiner

Aortic stenosis (AS) is a degenerative valve condition that causes substantial morbidity and mortality. This condition is under-diagnosed and under-treated. In clinical practice, AS is diagnosed with expert review of transthoracic…

Image and Video Processing · Electrical Eng. & Systems 2024-04-08 Zhe Huang , Benjamin S. Wessler , Michael C. Hughes

Investigation on the electrocardiogram (ECG) signals is an essential way to diagnose heart disease since the ECG process is noninvasive and easy to use. This work presents a supraventricular arrhythmia prediction model consisting of a few…

Signal Processing · Electrical Eng. & Systems 2021-12-28 Pampa Howladar , Manodipan Sahoo

The ability to perform accurate prognosis of patients is crucial for proactive clinical decision making, informed resource management and personalised care. Existing outcome prediction models suffer from a low recall of infrequent positive…

Ensemble learning is widely applied in Machine Learning (ML) to improve model performance and to mitigate decision risks. In this approach, predictions from a diverse set of learners are combined to obtain a joint decision. Recently,…

Machine Learning · Computer Science 2020-07-14 Yingshui Tan , Baihong Jin , Xiangyu Yue , Yuxin Chen , Alberto Sangiovanni Vincentelli

This study investigates the heterogeneity in survival times among COVID-19 patients with Heart Failure (HF) hospitalized in the Lombardy region of Italy during the pandemic. To address this, we propose a novel mixture model for…

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