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The question of how SARS-CoV-2 is transmitted remains surprisingly controversial today, especially with reference to airborne transmission. In fact, despite a large body of scientific evidence, health and regulatory authorities still…

Medical Physics · Physics 2021-10-07 G. Buonanno , A. Robotto , E. Brizio , L. Morawska , A. Civra , F. Corino , D. Lembo , G. Ficco , L. Stabile

Computational multi-scale pandemic modelling remains a major and timely challenge. Here we identify specific requirements for a new class of models simulating pandemics across three scales: (1) pathogen evolution, often punctuated by the…

Populations and Evolution · Quantitative Biology 2025-08-04 Quang Dang Nguyen , Sheryl L. Chang , Carl J. E. Suster , Rebecca J. Rockett , Vitali Sintchenko , Tania C. Sorrell , Mikhail Prokopenko

The world is suffering from a pandemic called COVID-19, caused by the SARS-CoV-2 virus. National governments have problems evaluating the reach of the epidemic, due to having limited resources and tests at their disposal. This problem is…

Throughout the course of an epidemic, the rate at which disease spreads varies with behavioral changes, the emergence of new disease variants, and the introduction of mitigation policies. Estimating such changes in transmission rates can…

Methodology · Statistics 2022-11-29 Jenny Huang , Raphaël Morsomme , David Dunson , Jason Xu

The world is still fighting against COVID-19, which has been lasting for more than a year. Till date, it has been a greatest challenge to human beings in fighting against COVID-19 since, the pathogen SARS-COV-2 that causes COVID-19 has…

Populations and Evolution · Quantitative Biology 2021-06-17 P. Tamilalagan , B. Krithika , P. Manivannan

When the novel coronavirus disease SARS-CoV2 (COVID-19) was officially declared a pandemic by the WHO in March 2020, the scientific community had already braced up in the effort of making sense of the fast-growing wealth of data gathered by…

Populations and Evolution · Quantitative Biology 2020-05-25 Timoteo Carletti , Duccio Fanelli , Francesco Piazza

The identification of the transmission parameters of a virus is fundamental to identify the optimal public health strategy. These parameters can present significant changes over time caused by genetic mutations or viral recombination,…

Populations and Evolution · Quantitative Biology 2022-07-21 Eugenio Lippiello , Giuseppe Petrillo , Lucilla de Arcangelis

Future SARS-CoV-2 virus outbreak COVID-XX might possibly occur during the next years. However the pathology in humans is so recent that many clinical aspects, like early detection of complications, side effects after recovery or early…

Image and Video Processing · Electrical Eng. & Systems 2020-05-29 D. Gil , K. Díaz-Chito , C. Sánchez , A. Hernández-Sabaté

Increasing number in global COVID-19 cases demands for mathematical model to analyze the interaction between the virus dynamics and the response of innate and adaptive immunity. Here, based on the assumption of a weak and delayed response…

Populations and Evolution · Quantitative Biology 2021-01-13 Zhengqing Zhou , Zhiheng Zhao , Shuyu Shi , Jianghua Wu , Dianjie Li , Jianwei Li , Jingpeng Zhang , Ke Gui , Yu Zhang , Heng Mei , Yu Hu , Qi Ouyang , Fangting Li

Monitoring the incidence of new infections during a pandemic is critical for an effective public health response. General population prevalence surveys for SARS-CoV-2 can provide high-quality data to estimate incidence. However, estimation…

The coronavirus disease (COVID-19) pandemic, caused by the coronavirus SARS-CoV-2, has caused 60 millions of infections and 1.38 millions of fatalities. Genomic analysis of SARS-CoV-2 can provide insights on drug design and vaccine…

Other Quantitative Biology · Quantitative Biology 2020-11-26 Changchuan Yin , Stephen S. -T. Yau

Several important aspects related to SARS-CoV-2 transmission are not well known due to a lack of appropriate data. However, mathematical and computational tools can be used to extract part of this information from the available data, like…

Populations and Evolution · Quantitative Biology 2022-04-01 Nicolas Franco , Pietro Coletti , Lander Willem , Leonardo Angeli , Adrien Lajot , Steven Abrams , Philippe Beutels , Christel Faes , Niel Hens

Severe acute respiratory disease SARS-CoV-2 has had a found impact on public health systems and healthcare emergency response especially with respect to making decisions on the most effective measures to be taken at any given time. As…

Machine Learning · Computer Science 2023-09-19 Charithea Stylianides , Kleanthis Malialis , Panayiotis Kolios

The COVID-19 pandemic response relied heavily on statistical and machine learning models to predict key outcomes such as case prevalence and fatality rates. These predictions were instrumental in enabling timely public health interventions…

In this paper, we propose a method to analyze correlations in pandemic-related data across different geographical regions, relying on the analysis of correlations for non-stationary time series, which are typical of pandemic data. Unlike…

Applications · Statistics 2026-04-06 Pablo Carlos López , Marcos Flores , Soham Biswas

COVID-19 disease, caused by SARS-CoV-2, has resulted in a global pandemic recently. With no approved vaccination or treatment, governments around the world have issued guidance to their citizens to remain at home in efforts to control the…

Computers and Society · Computer Science 2020-08-03 William Taylor , Qammer H. Abbasi , Kia Dashtipour , Shuja Ansari , Aziz Shah , Arslan Khan , Muhammad Ali Imran

The devastating impact of the COVID-19 pandemic caused by SARS coronavirus 2 (SARS CoV 2) has raised important questions about viral origin, mechanisms of zoonotic transfer to humans, whether companion or commercial animals can act as…

Biomolecules · Quantitative Biology 2021-07-12 Sakshi Piplani , Puneet Kumar Singh , David A. Winkler , Nikolai Petrovsky

The crisis caused by the COVID-19 outbreak around the globe raised an increasing concern about the ongoing emergence of variants of SARS-CoV-2 that may evade the immune response provided by vaccines. New variants appear due to mutation, and…

Populations and Evolution · Quantitative Biology 2022-12-14 M. Ahumada , A. Ledesma-Araujo , Leonardo Gordillo , Juan F. Marín

With the rapid global spread of COVID-19, more and more data related to this virus is becoming available, including genomic sequence data. The total number of genomic sequences that are publicly available on platforms such as GISAID is…

Genomics · Quantitative Biology 2021-11-16 Sarwan Ali , Murray Patterson

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has a variable clinical presentation that ranges from asymptomatic, to severe disease with cytokine storm. The mortality rates also differ across the globe, ranging from 0.5-13%.…