English
Related papers

Related papers: A pH-based bio-rheostat: a proof-of-concept

200 papers

The increasing interest in photoactivated proteins as natural replacement of standard inorganic materials in photocells drives to the compared analysis of bacteriorhodopsin and proteorhodopsin, two widely diffused proteins belonging to the…

Biological Physics · Physics 2015-06-16 E Alfinito , J Pousset , L Reggiani , K Lee

Photonic crystal-based biosensors hold great promise as valid and low-cost devices for real-time monitoring of a variety of biotargets. Given the high processability and easiness of read-out even for unskilled operators, these systems can…

An accurate map of intracellular organelle pH is crucial for comprehending cellular metabolism and organellar functions. However, a unified intracellular pH spectrum using a single probe is still lack. Here, we developed a novel quantum…

Quantitative Methods · Quantitative Biology 2024-07-08 Shu-Ang Li , Xiao-Yan Meng , Su Zhang , Ying-Jie Zhang , Run-Zhou Yang , Dian-Dian Wang , Yang Yang , Pei-Pei Liu , Jian-Sheng Kang

Recently, a growing interest has been addressed to the electrical properties of bacteriorhodopsin (bR), a protein belonging to the transmembrane protein family. To take into account the structure-dependent nature of the current, in a…

Soft Condensed Matter · Physics 2015-03-06 E. Alfinito , L. Reggiani

We have developed a cryogenic characterization platform for ultrafast photodiodes, whose time domain responses are extracted by electro-optic sampling using femtosecond laser pulses in a pump-probe configuration. The excitation of the…

Microfluidic systems with integrated sensors are ideal platforms to study and emulate processes such as complex multiphase flow and reactive transport in porous media, numerical modeling of bulk systems in medicine, and in engineering.…

Solid-state nanopore and nanopipette sensors are powerful devices for the detection, quantification and structural analysis of biopolymers such as DNA and proteins, especially in carrier-enhanced resistive-pulse sensing. However, hundreds…

Mesoscale and Nanoscale Physics · Physics 2025-10-14 Cengiz J. Khan , Oliver J. Irving , Rand A. Al-Waqfi , Giorgio Ferrari , Tim Albrecht

We present a physics-based circuit-compatible model for pH-sensitive field-effect transistors based on two-dimensional (2D) materials. The electrostatics along the electrolyte-gated 2D-semiconductor stack is treated by solving the Poisson…

The development of next generation medicines demand more sensitive and reliable label free sensing able to cope with increasing needs of multiplexing and shorter times to results. Field effect transistor-based biosensors emerge as one of…

Applied Physics · Physics 2019-05-22 Serena Rollo , Dipti Rani , Renaud Leturcq , Wouter Olthuis , César Pascual García

We report the fabrication and characterization of a simple gate-free graphene device as a pH sensor. The graphene sheets are made by mechanical exfoliation. Platinum contact electrodes are fabricated with a mask-free process using focused…

Materials Science · Physics 2012-07-05 Nan Lei , Pengfei Li , Wei Xue , Jie Xu

The pH response of liquid metal (eutectic GaInSn) in the form of a pendant drop is investigated and the sensitivity of 92.96 mV in the pH range from 4 to 10 is obtained. Unlike the fundamental limit of pH sensitivity of 59.1 mV in an…

Applied Physics · Physics 2024-09-05 Atanu Das

Although many exciting applications of molecular communication (MC) systems are envisioned to be at microscale, the MC testbeds reported so far are mostly at macroscale. To link the macroworld to the microworld, we propose and demonstrate a…

Optically-addressable spin qubits form the foundation of a new generation of emerging nanoscale sensors. The engineering of these sensors has mainly focused on solid-state systems such as the nitrogen-vacancy (NV) center in diamond.…

pH of a solution is the ratio of H+/OH- ions. The relative ratio of these charges may affect forming bonds during a hydrothermal synthesis by influencing electronic clouds of participant ions, which can modify the structure and hence…

Water plays a major role in bio-systems, greatly contributing to determine their structure, stability and even function. It is well know, for instance, that proteins require a minimum amount of water to be functionally active. Since the…

Biological Physics · Physics 2019-04-05 Antonio Benedetto

The evolution of particle detectors dates back to the discovery of X-rays and radioactivity in 1890s. In detector history, the Resistive Plate Chambers (RPCs) are introduced in early 1980s. An RPC is a gaseous detector made up of two…

Instrumentation and Detectors · Physics 2018-11-20 Manisha , V. Bhatnagar , J. S. Shahi , S. Verma , B. P. Mohanty , A. Kumar

Confocal fluorescence microscopy is a proven technique, which can image near-electrode pH changes. For a complete understanding of electrode processes, time-resolved measurements are required, which have not yet been provided. Here we…

A new, versatile, multiphasic buffer system for high-resolution sodium dodecyl sulfate-polyacrylamide gel electrophoresis of proteins in the relative molecular weight range of 300 000-3000 Da is described. The system, based on the theory of…

We implemented a nanoelectronic interface between graphene field effect transistors (FETs) and soluble proteins. This enables production of bioelectronic devices that combine functionalities of the biomolecular and inorganic components. The…

Mesoscale and Nanoscale Physics · Physics 2015-06-03 Ye Lu , Mitchell B. Lerner , Zhengqing John Qi , Joseph J. Mitala , Jong Hsien Lim , Bohdana M. Discher , A. T. Charlie Johnson

We realize a biochemical filtering process by introducing a buffer in a biocatalytic signal-transduction logic system based on the function of an enzyme, esterase. The input, ethyl butyrate, is converted into butyric acid-the output signal,…

Soft Condensed Matter · Physics 2017-09-13 Marcos Pita , Vladimir Privman , Mary A. Arugula , Dmitriy Melnikov , Vera Bocharova , Evgeny Katz