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Recent advances in 3D fully convolutional networks (FCN) have made it feasible to produce dense voxel-wise predictions of full volumetric images. In this work, we show that a multi-class 3D FCN trained on manually labeled CT scans of seven…

Computer Vision and Pattern Recognition · Computer Science 2017-04-24 Holger R. Roth , Hirohisa Oda , Yuichiro Hayashi , Masahiro Oda , Natsuki Shimizu , Michitaka Fujiwara , Kazunari Misawa , Kensaku Mori

Cancer patients have a higher risk of cardiovascular disease (CVD) mortality than the general population. Low dose computed tomography (LDCT) for lung cancer screening offers an opportunity for simultaneous CVD risk estimation in at-risk…

Image and Video Processing · Electrical Eng. & Systems 2021-06-09 Hanqing Chao , Hongming Shan , Fatemeh Homayounieh , Ramandeep Singh , Ruhani Doda Khera , Hengtao Guo , Timothy Su , Ge Wang , Mannudeep K. Kalra , Pingkun Yan

Automated blood vessel segmentation is vital for biomedical imaging, as vessel changes indicate many pathologies. Still, precise segmentation is difficult due to the complexity of vascular structures, anatomical variations across patients,…

The aetiology of head and neck squamous cell carcinoma (HNSCC) involves multiple carcinogens such as alcohol, tobacco and infection with human papillomavirus (HPV). As the HPV infection influences the prognosis, treatment and survival of…

Computer Vision and Pattern Recognition · Computer Science 2022-06-17 Ruoyu Wang , Syed Ali Khurram , Amina Asif , Lawrence Young , Nasir Rajpoot

Motivation: Hepatocellular carcinoma (HCC) is a significant health problem worldwide and annual number of cases are nearly more than 700,000. However,there are few safe and effective thera-peutic options for HCC patients.Here, we propose a…

Tissues and Organs · Quantitative Biology 2017-07-05 Liang Yu , Fengdan Xu , Lin Gao

Summary mean DCE-MRI variables show a clear dependency between signal and noise variance, which can be shown to reduce the effectiveness of difference assessments. Appropriate transformation of these variables supports statistically…

Medical Physics · Physics 2023-03-20 S. V. Notley , N. A. Thacker , L. Horsley , R. A. Little , Y. Watson , S. Mullamitha , G. C. Jayson , A. Jackson

Pancreatic ductal adenocarcinoma (PDAC) is one of the most lethal cancers among the population. Screening for PDACs in dynamic contrast-enhanced CT is beneficial for early diagnosis. In this paper, we investigate the problem of automated…

Image and Video Processing · Electrical Eng. & Systems 2020-07-03 Yingda Xia , Qihang Yu , Wei Shen , Yuyin Zhou , Elliot K. Fishman , Alan L. Yuille

For many patients, current ovarian cancer treatments offer limited clinical benefit. For some therapies, it is not possible to predict patients' responses, potentially exposing them to the adverse effects of treatment without any…

Image and Video Processing · Electrical Eng. & Systems 2023-10-20 Jack Breen , Katie Allen , Kieran Zucker , Geoff Hall , Nishant Ravikumar , Nicolas M. Orsi

Pathological features are the gold standard for tumor diagnosis, guiding treatment and prognosis. However, standard histopathological process is labor-intensive and time-consuming, while frozen sections have lower accuracy. Dynamic…

Diagnosing basal cell carcinomas (BCC), one of the most common cutaneous malignancies in humans, is a task regularly performed by pathologists and dermato-pathologists. Improving histological diagnosis by providing diagnosis suggestions,…

Accurate histological differentiation between adenocarcinoma (ADC) and squamous cell carcinoma (SCC) is critical for personalized treatment in non-small cell lung cancer (NSCLC). While [$^{18}$F]FDG PET/CT is a standard tool for the…

Computer Vision and Pattern Recognition · Computer Science 2026-05-05 Fatih Aksu , Laura Ciuffetti , Francesco Di Feola , Filippo Ruffini , Giulia Romoli , Fabrizia Gelardi , Arturo Chiti , Valerio Guarrasi , Paolo Soda

The diagnosis of primary liver cancers (PLCs) can be challenging, especially on biopsies and for combined hepatocellular-cholangiocarcinoma (cHCC-CCA). We automatically classified PLCs on routine-stained biopsies using a weakly supervised…

This study introduces an automated pipeline for renal cancer (RC) detection in non-contrast computed tomography (NCCT). In the development of our pipeline, we test three detections models: a shape model, a 2D-, and a 3D axial-sample model.…

Image and Video Processing · Electrical Eng. & Systems 2023-12-12 William McGough , Thomas Buddenkotte , Stephan Ursprung , Zeyu Gao , Grant Stewart , Mireia Crispin-Ortuzar

Semantic segmentation of electron microscopy (EM) is an essential step to efficiently obtain reliable morphological statistics. Despite the great success achieved using deep convolutional neural networks (CNNs), they still produce coarse…

Computer Vision and Pattern Recognition · Computer Science 2021-01-11 Zhimin Yuan , Xiaofen Ma , Jiajin Yi , Zhengrong Luo , Jialin Peng

We present an effective application of quantum machine learning in the field of healthcare. The study here emphasizes on a classification problem of a histopathological cancer detection using quantum transfer learning. Rather than using…

Quantum Physics · Physics 2023-02-10 Reek Majumdar , Biswaraj Baral , Bhavika Bhalgamiya , Taposh Dutta Roy

The complementary information found in different modalities of patient data can aid in more accurate modelling of a patient's disease state and a better understanding of the underlying biological processes of a disease. However, the…

Machine Learning · Computer Science 2025-04-18 Annette Spooner , Mohammad Karimi Moridani , Azadeh Safarchi , Salim Maher , Fatemeh Vafaee , Amany Zekry , Arcot Sowmya

Invasive ductal carcinoma (IDC) is the most prevalent form of breast cancer, and early, accurate diagnosis is critical to improving patient survival rates by guiding treatment decisions. Combining medical expertise with artificial…

Image and Video Processing · Electrical Eng. & Systems 2025-08-12 Shuo Han , Ahmed Karam Eldaly , Solomon Sunday Oyelere

Cancer is a heterogeneous disease with diverse molecular etiologies and outcomes. The Cancer Genome Atlas (TCGA) has released a large compendium of over 10,000 tumors with RNA-seq gene expression measurements. Gene expression captures the…

Genomics · Quantitative Biology 2017-11-15 Gregory P. Way , Casey S. Greene

Background. Subdural hematoma (SDH) is a common neurosurgical emergency, with increasing incidence in aging populations. Rapid and accurate identification is essential to guide timely intervention, yet existing automated tools focus…

Computer Vision and Pattern Recognition · Computer Science 2025-12-11 Vasiliki Stoumpou , Rohan Kumar , Bernard Burman , Diego Ojeda , Tapan Mehta , Dimitris Bertsimas