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Opioid Use Disorder (OUD) has reached an epidemic level in the US. Diversion of unused prescription opioids to secondary users and black market significantly contributes to the abuse and misuse of these highly addictive drugs, leading to…

Optimization and Control · Mathematics 2022-10-17 Md Mahmudul Hasan , Tasnim Ibn Faiz , Alicia Sasser Modestino , Gary J. Young , Md. Noor-E-Alam

Faced with data-driven policies, individuals will manipulate their features to obtain favorable decisions. While earlier works cast these manipulations as undesirable gaming, recent works have adopted a more nuanced causal framing in which…

Machine Learning · Computer Science 2023-02-22 Tom Yan , Shantanu Gupta , Zachary Lipton

Speeding has been acknowledged as a critical determinant in increasing the risk of crashes and their resulting injury severities. This paper demonstrates that severe speeding-related crashes within the state of Pennsylvania have a spatial…

Applications · Statistics 2023-09-22 Renteng Yuan , Qiaojun Xiang , Zhiheng Fang , Xin Gu

Machine learning is traditionally studied at the model level: researchers measure and improve the accuracy, robustness, bias, efficiency, and other dimensions of specific models. In practice, the societal impact of machine learning is…

Machine Learning · Computer Science 2024-04-04 Connor Toups , Rishi Bommasani , Kathleen A. Creel , Sarah H. Bana , Dan Jurafsky , Percy Liang

Medication errors continue to be the leading cause of avoidable patient harm in hospitals. This paper sets out a framework to assure medication safety that combines machine learning and safety engineering methods. It uses safety analysis to…

Machine Learning · Computer Science 2021-01-15 Yan Jia , Tom Lawton , John McDermid , Eric Rojas , Ibrahim Habli

We conducted a prospective analysis of incident dementia and its association with 65 sociodemographic, early-life, economic, health and behavioral, social, and genetic risk factors in a sample of 7,908 adults over the age of 50 from the…

Applications · Statistics 2021-01-27 Jordan Weiss , Eli Puterman , Aric A. Prather , Erin B. Ware , David H. Rehkopf

The complex unfolding of the US opioid epidemic in the last 20 years has been the subject of a large body of medical and pharmacological research, and it has sparked a multidisciplinary discussion on how to implement interventions and…

Computers and Society · Computer Science 2021-02-23 Duilio Balsamo , Paolo Bajardi , Alberto Salomone , Rossano Schifanella

Many social programs attempt to allocate scarce resources to people with the greatest need. Indeed, public services increasingly use algorithmic risk assessments motivated by this goal. However, targeting the highest-need recipients often…

Machine Learning · Computer Science 2025-06-30 Bryan Wilder , Pim Welle

Motivated by the study of state opioid policies, we propose a novel approach that uses autoregressive models for causal effect estimation in settings with panel data and staggered treatment adoption. Specifically, we seek to estimate the…

Understanding the causes of crime is a longstanding issue in researcher's agenda. While it is a hard task to extract causality from data, several linear models have been proposed to predict crime through the existing correlations between…

Physics and Society · Physics 2018-04-10 Luiz G A Alves , Haroldo V Ribeiro , Francisco A Rodrigues

Much attention and concern has been raised recently about bias and the use of machine learning algorithms in healthcare, especially as it relates to perpetuating racial discrimination and health disparities. Following an initial system…

Machine Learning · Computer Science 2023-05-24 Jill A. Kuhlberg , Irene Headen , Ellis A. Ballard , Donald Martin

We investigate estimation of causal effects of multiple competing (multi-valued) treatments in the absence of randomization. Our work is motivated by an intention-to-treat study of the relative cardiometabolic risk of assignment to one of…

Drug-drug interactions (DDIs) are a leading cause of preventable adverse events, often complicating treatment and increasing healthcare costs. At the same time, knowing which drugs do not interact is equally important, as such knowledge…

Machine Learning · Computer Science 2026-01-08 Maryam Abdollahi Shamami , Babak Teimourpour , Farshad Sharifi

Substances of abuse are known to activate and disrupt neuronal circuits in the brain reward system. We propose a simple and easily interpretable dynamical systems model to describe the neurobiology of drug addiction that incorporates the…

Neurons and Cognition · Quantitative Biology 2026-05-12 Tom Chou , Maria D'Orsogna

Scientific evidence confirm that significant racial disparities exist in healthcare, including surgery outcomes. However, the causal pathway underlying disparities at preoperative physical condition of children is not well-understood. This…

Computers and Society · Computer Science 2021-04-12 Oguz Akbilgic , Eun Kyong Shin , Arash Shaban-Nejad

Lung cancer (LC) is a leading cause of cancer-related mortality in the United States. Accurate prediction of LC mortality rates is crucial for guiding targeted interventions and addressing health disparities. Although traditional…

Machine Learning · Computer Science 2025-12-23 Soheil Hashtarkhani , Brianna M. White , Benyamin Hoseini , David L. Schwartz , Arash Shaban-Nejad

We consider the problem in precision health of grouping people into subpopulations based on their degree of vulnerability to a risk factor. These subpopulations cannot be discovered with traditional clustering techniques because their…

Machine Learning · Statistics 2018-12-11 Alexander New , Kristin P. Bennett

A major public health concern in the United States (US) is gun-related deaths. The number of gun injuries largely varies spatially because of county-wise heterogeneity of race, sex, age, and income distributions. But still, a major…

Methodology · Statistics 2026-01-28 Debjoy Thakur , Lingyuan Zhao , Soutir Bandyopadhyay

Background: Pediatric dental disease remains one of the most prevalent and inequitable chronic health conditions worldwide. Although strong epidemiological evidence links oral health outcomes to socio-economic and demographic determinants,…

Machine Learning · Computer Science 2026-01-21 Manasi Kanade , Abhi Thakkar , Gabriela Fernandes

Our recent experience with the COVID-19 pandemic amply shows that spatial effects like the mobility of agents and average interpersonal distance, together with the adaptation of agents, are very important in deciding the outcome of epidemic…

Physics and Society · Physics 2025-01-13 Akhil Panicker , V Sasidevan