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We introduce Adjoint Sampling, a highly scalable and efficient algorithm for learning diffusion processes that sample from unnormalized densities, or energy functions. It is the first on-policy approach that allows significantly more…

This paper deals with linear equalization in massive multi-user multiple-input multiple-output (MU-MIMO) wireless systems. We first provide simple conditions on the antenna configuration for which the well-known linear minimum mean-square…

Information Theory · Computer Science 2018-11-12 Ramina Ghods , Charles Jeon , Gulnar Mirza , Arian Maleki , Christoph Studer

Nanopore resistive pulse techniques are based on analysis of current or voltage spikes in the recorded signal. These spikes result from translocation of nanometer sized analytes through a nanopore. The most important information that needs…

Data Analysis, Statistics and Probability · Physics 2015-03-13 Nima Arjmandi , Willem Van Roy , Liesbet Lagae , Gustaaf Borghs

Continuously optimizing sensor placement is essential for precise target localization in various military and civilian applications. While information theory has shown promise in optimizing sensor placement, many studies oversimplify sensor…

We present the first general purpose framework for marginal maximum a posteriori estimation of probabilistic program variables. By using a series of code transformations, the evidence of any probabilistic program, and therefore of any…

Machine Learning · Statistics 2017-07-17 Tom Rainforth , Tuan Anh Le , Jan-Willem van de Meent , Michael A. Osborne , Frank Wood

We conducted an extensive computational experiment, lasting multiple CPU-years, to optimally select parameters for two important classes of algorithms for finding sparse solutions of underdetermined systems of linear equations. We make the…

Numerical Analysis · Computer Science 2015-05-14 Arian Maleki , David L. Donoho

We develop a set of algorithms to solve a broad class of Design of Experiment (DoE) problems efficiently. Specifically, we consider problems in which one must choose a subset of polymers to test in experiments such that the learning of the…

Quantitative Methods · Quantitative Biology 2024-08-06 Swagatam Mukhopadhyay

The success of ptychographic imaging experiments strongly depends on achieving high signal-to-noise ratio. This is particularly important in nanoscale imaging experiments when diffraction signals are very weak and the experiments are…

Image and Video Processing · Electrical Eng. & Systems 2019-06-10 Huibin Chang , Pablo Enfedaque , Jie Zhang , Juliane Reinhardt , Bjoern Enders , Young-Sang Yu , David Shapiro , Christian G. Schroer , Tieyong Zeng , Stefano Marchesini

Pose estimation is still a challenge at the small scales. Few solutions exist to capture the 6 degrees of freedom of an object with nanometric and microradians resolutions over relatively large ranges. Over the years, we have proposed…

Computer Vision and Pattern Recognition · Computer Science 2025-10-06 Patrick Sandoz , Antoine N. André , Guillaume J. Laurent

Compressed sensing (CS) is a signal processing technique that enables the efficient recovery of a sparse high-dimensional signal from low-dimensional measurements. In the multiple measurement vector (MMV) framework, a set of signals with…

Signal Processing · Electrical Eng. & Systems 2022-06-08 Pavan K. Kota , Daniel LeJeune , Rebekah A. Drezek , Richard G. Baraniuk

Noise Contrastive Estimation (NCE) has fueled major breakthroughs in representation learning and generative modeling. Yet a long-standing challenge remains: accurately estimating ratios between distributions that differ substantially, which…

The hyperpolarisation of nuclear spins within target molecules is a critical and complex challenge in magnetic resonance imaging (MRI) and nuclear magnetic resonance (NMR) spectroscopy. Hyperpolarisation offers enormous gains in signal and…

We describe an optimal signal extraction process for imaging X-ray polarimetry using an ensemble of deep neural networks. The initial photo-electron angle, used to recover the polarization, has errors following a von Mises distribution.…

Instrumentation and Methods for Astrophysics · Physics 2021-10-20 A. L. Peirson , R. W. Romani

Single-spin quantum sensors, for example based on nitrogen-vacancy centres in diamond, provide nanoscale mapping of magnetic fields. In applications where the magnetic field may be changing rapidly, total sensing time is crucial and must be…

Quantum Physics · Physics 2021-05-26 K. Craigie , E. M. Gauger , Y. Altmann , C. Bonato

Recent work has shown constrained Bayesian optimization to be a powerful technique for the optimization of industrial processes. In complex manufacturing processes, the possibility to run extensive sequences of experiments with the goal of…

Systems and Control · Electrical Eng. & Systems 2022-05-12 Xavier Guidetti , Alisa Rupenyan , Lutz Fassl , Majid Nabavi , John Lygeros

Nuclear magnetic resonance (NMR) spectroscopy is one of the leading techniques for protein studies. The method features a number of properties, allowing to explain macromolecular interactions mechanistically and resolve structures with…

Quantitative Methods · Quantitative Biology 2018-08-03 Piotr Klukowski , Adam Gonczarek

We introduce Neural Optimal Design of Experiments, a learning-based framework for optimal experimental design in inverse problems that avoids classical bilevel optimization and indirect sparsity regularization. NODE jointly trains a neural…

Machine Learning · Computer Science 2026-01-08 John E. Darges , Babak Maboudi Afkham , Matthias Chung

Recently, sparsity-based algorithms are proposed for super-resolution spectrum estimation. However, to achieve adequately high resolution in real-world signal analysis, the dictionary atoms have to be close to each other in frequency,…

Machine Learning · Statistics 2015-06-05 Yiyuan She , Huanghuang Li , Jiangping Wang , Dapeng Wu

Deep model-based architectures (DMBAs) integrating physical measurement models and learned image regularizers are widely used in parallel magnetic resonance imaging (PMRI). Traditional DMBAs for PMRI rely on pre-estimated coil sensitivity…

Image and Video Processing · Electrical Eng. & Systems 2024-06-07 Yuyang Hu , Weijie Gan , Chunwei Ying , Tongyao Wang , Cihat Eldeniz , Jiaming Liu , Yasheng Chen , Hongyu An , Ulugbek S. Kamilov

Research challenges encountered across science, engineering, and economics can frequently be formulated as optimization tasks. In chemistry and materials science, recent growth in laboratory digitization and automation has sparked interest…