Related papers: Large-scale cortex-core structure formation in bra…
The relative importance of the intrinsic and extrinsic factors determining the variety of geometric shapes exhibited by dendritic trees remains unclear. This question was addressed by developing a model of the growth of dendritic trees…
The corpus callosum, the largest white matter structure in the brain, plays a critical role in interhemispheric communication. Variations in its morphology are associated with various neurological and psychological conditions, making it a…
The cell cortex, a thin film of active material assembled below the cell membrane, plays a key role in cellular symmetry breaking processes such as cell polarity establishment and cell division. Here, we present a minimal model of the…
Structural and functional heterogeneity are hallmarks of cortical circuits, from broad degree distributions in the mouse connectome to diverse intrinsic neuronal timescales. Yet a mechanistic link between connectivity heterogeneity and…
The connectome, a map of the structural and/or functional connections in the brain, provides a complex representation of the neurobiological phenotypes on which it supervenes. This information-rich data modality has the potential to…
In multicellular organisms, relations among parts and between parts and the whole are contextual and interdependent. These organisms and their cells are ontogenetically linked: an organism starts as a cell that divides producing…
Living systems implement and execute an extraordinary plethora of computational tasks. The inherent degree of large scale coordination emerges as a global property, from the intricate sea of microscopic interactions. The brain, with its…
There is increasing evidence on the importance of brain morphology in predicting and classifying mental disorders. However, the vast majority of current shape approaches rely heavily on vertex-wise analysis that may not successfully capture…
Many organs of higher organisms are heavily branched structures and arise by an at first sight similar process of branching morphogenesis. Yet the regulatory components and local interactions that have been identified differ greatly in…
Among the versatile forms of dynamical patterns of activity exhibited by the brain, oscillations are one of the most salient and extensively studied, yet are still far from being well understood. In this paper, we provide various structural…
Variants of the Kohonen model are proposed to study biological principles of self-organization in a model of young brain. We suggest a function to measure aquired knowledge and use it to auto-adapt the topology of neuronal connectivity,…
Functional brain network has been widely studied to understand the relationship between brain organization and behavior. In this paper, we aim to explore the functional connectivity of brain network under a \emph{multi-step} cognitive task…
Self-organization is the generation of order out of local interactions in non-equilibrium [1]. It is deeply connected to all fields of science from physics, chemistry to biology where functional living structures self-assemble[2] and…
How human brain function emerges from structure has intrigued researchers for decades and numerous models have been put forward, yet none of them yields a close structure-function relation. Here we present a resonance model based on…
The brain's functional diversity is reflected in the meso-scale architecture of its connectome, i.e. its division into clusters and communities of topologically-related brain regions. The dominant view, and one that is reinforced by current…
The bulk of the research effort on brain connectivity revolves around statistical associations among brain regions, which do not directly relate to the causal mechanisms governing brain dynamics. Here we propose the multiscale causal…
The human brain is a complex system defined by multi-way, higher-order interactions invisible to traditional pairwise network models. Although a diverse array of analytical methods has been developed to address this shortcoming, the field…
The dynamics of cellular pattern formation is crucial for understanding embryonic development and tissue morphogenesis. Recent studies have shown that human dermal fibroblasts cultured on liquid crystal elastomers can exhibit an increase in…
Oscillatory activities are widely observed in specific frequency bands of recorded field potentials in different brain regions, and play critical roles in processing neural information. Understanding the structure of these oscillatory…
A critical mystery in neuroscience lies in determining how anatomical structure impacts the complex functional dynamics of human thought. How does large-scale brain circuitry constrain states of neuronal activity and transitions between…