Related papers: High resolution transcranial imaging based on the …
Transcranial ultrasound imaging is usually limited by skull-induced attenuation and high-order aberrations. By using contrast agents such as microbubbles in combination with ultrafast imaging, not only can the signal-to-noise ratio be…
Spatial resolution in optical microscopy has traditionally been treated as a fixed parameter of the optical system. Here, we present an approach to enhance transverse resolution in beam-scanned optical coherence tomography (OCT) beyond its…
Segmentation of biomedical images is essential for studying and characterizing anatomical structures, detection and evaluation of pathological tissues. Segmentation has been further shown to enhance the reconstruction performance in many…
Imaging inside scattering media at optical resolution is a longstanding challenge affecting multiple fields, from bio-medicine to astronomy. In recent years, several groundbreaking techniques for imaging inside scattering media, in…
Optoacoustic tomography image reconstruction has been a problem of interest in recent years. By exploiting the exceptional generative power of the recently proposed diffusion models we consider a scheme which is based on a conditional…
High resolution optical microscopy is essential in neuroscience but suffers from scattering in biological tissues. It therefore grants access to superficial layers only. Recently developed techniques use scattered photons for imaging by…
A novel approach to improving the performances of confocal scanning imaging is proposed. We experimentally demonstrate its feasibility using acoustic waves. It relies on a new way to encode spatial information using the temporal dimension.…
Conventional photoacoustic imaging may suffer from the limited view and bandwidth of ultrasound transducers. A deep learning approach is proposed to handle these problems and is demonstrated both in simulations and in experiments on a…
Photoacoustic imaging (PAI) is a promising approach to realize in vivo transcranial cerebral vascular imaging. However, the strong attenuation and distortion of the photoacoustic wave caused by the thick porous skull greatly affect the…
Optical microscopy has so far been restricted to superficial layers, leaving many important biological questions unanswered. Random scattering causes the ballistic focus, which is conventionally used for image formation, to decay…
Background: Individual skull models of bone density and geometry are important when planning the expected transcranial ultrasound acoustic field and estimating mechanical and thermal safety in low-intensity transcranial ultrasound…
Transcranial photoacoustic computed tomography (PACT) is an emerging neuroimaging modality, but skull-induced aberrations can result in severe image artifacts if not compensated for during image reconstruction. The development of advanced…
Herein we report the first in-human transcranial imaging of brain function using photoacoustic computed tomography. Functional responses to benchmark motor tasks were imaged on both the skull-less and the skull-intact hemispheres of a…
Deep, high-resolution imaging is essential for unraveling biological complexity and advancing medical diagnostics, yet scattering fundamentally limits optical methods. Among the most promising approaches, photoacoustic imaging achieves…
Controlling light propagation across scattering media by wavefront shaping holds great promise for a wide range of communications and imaging applications. However, finding the right wavefront to shape is a challenge when the mapping…
Human skull poses a significant barrier for the propagation of ultrasound waves. Development of methods enabling more efficient ultrasound transmission into and from the brain is therefore critical for the advancement of ultrasound-mediated…
In ultrasound tomography, the speed of sound inside an object is estimated based on acoustic measurements carried out by sensors surrounding the object. An accurate forward model is a prominent factor for high-quality image reconstruction,…
Ultrasound brain imaging remains challenging due to the large difference in sound speed between the skull and brain tissues and the difficulty of coupling large probes to the skull. This work aims to achieve quantitative transcranial…
Photoacoustic imaging (PAI), by combining high optical contrast with ultrasonic resolution, offers a promising noninvasive approach for dynamic monitoring of cerebral vasculature. However, transcranial PAI still faces significant challenges…
Existing ultrasound deconvolution approaches unrealistically assume, primarily for computational reasons, that the convolution model relies on a spatially invariant kernel and circulant boundary conditions. We discard both restrictions and…