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For whole-body (WB) kinetic modeling based on a typical PET scanner, a multi-pass multi-bed scanning protocol is necessary given the limited axial field-of-view. Such a protocol introduces loss of early-dynamics in time-activity curves…

Medical Physics · Physics 2024-05-14 Kyung-Nam Lee , Arman Rahmim , Carlos Uribe

Positron Emission Tomography (PET) /Computed Tomography (CT) is crucial for diagnosing, managing, and planning treatment for various cancers. Developing reliable deep learning models for the segmentation of tumor lesions in PET/CT scans in…

Image and Video Processing · Electrical Eng. & Systems 2024-09-24 Tanya Chutani , Saikiran Bonthu , Pranab Samanta , Nitin Singhal

To obtain high-quality positron emission tomography (PET) scans while reducing radiation exposure to the human body, various approaches have been proposed to reconstruct standard-dose PET (SPET) images from low-dose PET (LPET) images. One…

Image and Video Processing · Electrical Eng. & Systems 2023-08-22 Zeyu Han , Yuhan Wang , Luping Zhou , Peng Wang , Binyu Yan , Jiliu Zhou , Yan Wang , Dinggang Shen

Dynamic positron emission tomography (PET) with [$^{18}$F]FDG enables non-invasive quantification of glucose metabolism through kinetic analysis, often modelled by the two-tissue compartment model (TCKM). However, voxel-wise kinetic…

Image and Video Processing · Electrical Eng. & Systems 2025-04-25 Kartikay Tehlan , Thomas Wendler

Patient motion is well-known for degrading image quality during medical imaging. Especially positron emission tomography (PET) is susceptible to motion due to its usually long scan times. In hybrid PET/MRI (magnetic resonance imaging),…

Medical Physics · Physics 2019-05-21 Lynn Johann Frohwein , Florian Büther , Klaus Peter Schäfers

We propose a novel dynamic image reconstruction method from PET listmode data that could be particularly suited to tracking single or small numbers of cells. In contrast to conventional PET reconstruction our method combines the information…

Computer Vision and Pattern Recognition · Computer Science 2019-11-25 Bernhard Schmitzer , Klaus P. Schäfers , Benedikt Wirth

Tumor segmentation in medical imaging is crucial and relies on precise delineation. Fluorodeoxyglucose Positron-Emission Tomography (FDG-PET) is widely used in clinical practice to detect metabolically active tumors. However, FDG-PET scans…

Image and Video Processing · Electrical Eng. & Systems 2023-10-05 Matthias Hadlich , Zdravko Marinov , Rainer Stiefelhagen

This paper describes the characterization of crystal matrices and silicon photomultiplier arrays for a novel Positron Emission Tomography (PET) detector, namely the external plate of the EndoTOFPET-US system. The EndoTOFPET-US collaboration…

Low-resolution and signal-dependent noise distribution in positron emission tomography (PET) images makes denoising process an inevitable step prior to qualitative and quantitative image analysis tasks. Conventional PET denoising methods…

Computer Vision and Pattern Recognition · Computer Science 2014-07-14 Awais Mansoor , Ulas Bagci , Daniel J. Mollura

To acquire high-quality positron emission tomography (PET) images while reducing the radiation tracer dose, numerous efforts have been devoted to reconstructing standard-dose PET (SPET) images from low-dose PET (LPET). However, the success…

Image and Video Processing · Electrical Eng. & Systems 2024-07-31 Jiaqi Cui , Pinxian Zeng , Yuanyuan Xu , Xi Wu , Jiliu Zhou , Yan Wang

Detector developments are currently enabling new capabilities in the field of transmission electron microscopy (TEM). We have investigated the limits of a hybrid pixel detector, Medipix3, to record dynamic, time varying, electron signals.…

Instrumentation and Detectors · Physics 2019-12-17 Gary W. Paterson , Raymond J. Lamb , Rafael Ballabriga , Dima Maneuski , Val O'Shea , Damien McGrouther

Recent advancements in ultra-high-resolution unpaired image-to-image translation have aimed to mitigate the constraints imposed by limited GPU memory through patch-wise inference. Nonetheless, existing methods often compromise between the…

Computer Vision and Pattern Recognition · Computer Science 2024-07-08 Ming-Yang Ho , Che-Ming Wu , Min-Sheng Wu , Yufeng Jane Tseng

Pancreatic cancer with more than 60,000 new cases each year has less than 10 percent 5-year overall survival. Radiation therapy (RT) is an effective treatment for Locally advanced pancreatic cancer (LAPC). The current clinical RT workflow…

Medical Physics · Physics 2023-06-07 Hamed Hooshangnejad , Quan Chen , Xue Feng , Rui Zhang , Kai Ding

Four-dimensional computed tomography (4DCT) has been widely used in cancer radiotherapy for accurate target delineation and motion measurement for tumors in thorax and upper abdomen areas. However, 4DCT simulation is associated with much…

Medical Physics · Physics 2015-05-19 Zhen Tian , Xun Jia , Steve B. Jiang

Objective: Dynamic cone-beam CT (CBCT) imaging is highly desired in image-guided radiation therapy to provide volumetric images with high spatial and temporal resolutions to enable applications including tumor motion tracking/prediction and…

Medical Physics · Physics 2023-02-22 You Zhang , Tielige Mengke

Positron Emission Tomography (PET) is an important clinical imaging tool but inevitably introduces radiation hazards to patients and healthcare providers. Reducing the tracer injection dose and eliminating the CT acquisition for attenuation…

Computer Vision and Pattern Recognition · Computer Science 2024-06-18 Tianqi Chen , Jun Hou , Yinchi Zhou , Huidong Xie , Xiongchao Chen , Qiong Liu , Xueqi Guo , Menghua Xia , James S. Duncan , Chi Liu , Bo Zhou

In recent years, the integration of advanced imaging techniques and deep learning methods has significantly advanced computer-aided diagnosis (CAD) systems for breast cancer detection and classification. Transformers, which have shown great…

Computer Vision and Pattern Recognition · Computer Science 2025-07-22 Mahtab Ranjbar , Mehdi Mohebbi , Mahdi Cherakhloo , Bijan Vosoughi. Vahdat

Differentiating tumor progression (TP) from treatment-related necrosis (TN) is critical for clinical management decisions in glioblastoma (GBM). Dynamic FDG PET (dPET), an advance from traditional static FDG PET, may prove advantageous in…

Image and Video Processing · Electrical Eng. & Systems 2023-03-01 Tonmoy Hossain , Zoraiz Qureshi , Nivetha Jayakumar , Thomas Eluvathingal Muttikkal , Sohil Patel , David Schiff , Miaomiao Zhang , Bijoy Kundu

Positron Emission Mammography imaging system (PEMi) is a nuclear medicine diagnosis method dedicated for breast imaging. It provides a better resolution in detection of millimeter-sized breast tumors than whole-body PET. To address the…

Medical Physics · Physics 2015-10-28 Xiao-Yue Gu , Lin Li , Peng-Fei Yin , Ming-Kai Yun , Chai Pei , Xin Fan , Xian-Chao Huang , Xiao-Li Sun , Long Wei

Positron Emission Tomography (PET) imaging requires accurate attenuation correction (AC) to account for photon loss due to tissue density variations. In PET/MR systems, computed tomography (CT), which offers a straightforward estimation of…

Image and Video Processing · Electrical Eng. & Systems 2025-04-11 Weijie Chen , James Wang , Alan McMillan
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