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Inference of the marginal likelihood of sample allele configurations using backward algorithms yields identical results with the Kingman coalescent, the Moran model, and the diffusion model (up to a scaling of time). For inference of…

Populations and Evolution · Quantitative Biology 2021-12-20 Claus Vogl , Sandra Peer , Lynette Caitlin Mikula

The evolutionary processes of complex systems contain critical information regarding their functional characteristics. The generation time of edges provides insights into the historical evolution of various networked complex systems, such…

Artificial Intelligence · Computer Science 2025-01-14 En Xu , Can Rong , Jingtao Ding , Yong Li

Although extensive behavioral changes often exist between closely related animal species, our understanding of the genetic basis underlying the evolution of behavior has remained limited. Here, we propose a new framework to study behavioral…

Populations and Evolution · Quantitative Biology 2020-07-21 Damián G. Hernández , Catalina Rivera , Jessica Cande , Baohua Zhou , David L. Stern , Gordon J. Berman

Research shows that gene duplication followed by either repurposing or removal of duplicated genes is an important contributor to evolution of gene and protein interaction networks. We aim to identify which characteristics of a network can…

Molecular Networks · Quantitative Biology 2021-07-27 Peter Crawford-Kahrl , Robert R. Nerem , Bree Cummins , Tomas Gedeon

Molecular phylogeny has focused mainly on improving models for the reconstruction of gene trees based on sequence alignments. Yet, most phylogeneticists seek to reveal the history of species. Although the histories of genes and species are…

Populations and Evolution · Quantitative Biology 2013-11-05 Gergely J. Szöllosi , Eric Tannier , Vincent Daubin , Bastien Boussau

We investigate a recurrent neural network model with common external and bias inputs that can retrieve branching sequences. Retrieval of memory sequences is one of the most important functions of the brain. A lot of research has been done…

Disordered Systems and Neural Networks · Physics 2009-11-13 Kentaro Katahira , Masaki Kawamura , Kazuo Okanoya , Masato Okada

Continuous input signals like images and time series that are irregularly sampled or have missing values are challenging for existing deep learning methods. Coherently defined feature representations must depend on the values in unobserved…

Machine Learning · Computer Science 2020-10-22 Marc Finzi , Roberto Bondesan , Max Welling

We consider the problem of estimating the evolutionary history of a set of species (phylogeny or species tree) from several genes. It is known that the evolutionary history of individual genes (gene trees) might be topologically distinct…

Populations and Evolution · Quantitative Biology 2016-11-18 Gautam Dasarathy , Robert Nowak , Sebastien Roch

We consider the reconciliation problem, in which the task is to find a mapping of a gene tree into a species tree, so as to maximize the likelihood of such fitting, given the available data. We describe a model for the evolution of the…

Populations and Evolution · Quantitative Biology 2023-11-09 Albert C. Soewongsono , Jiahao Diao , Tristan Stark , Amanda E. Wilson , David A. Liberles , Barbara R. Holland , Malgorzata M. O'Reilly

1. Deciphering coexistence patterns is a current challenge to understanding diversity maintenance, especially in rich communities where the complexity of these patterns is magnified through indirect interactions that prevent their…

Machine Learning · Computer Science 2021-07-14 J. Hirn , J. E. García , A. Montesinos-Navarro , R. Sanchez-Martín , V. Sanz , M. Verdú

Reconstructing ancestral gene orders in a given phylogeny is a classical problem in comparative genomics. Most existing methods compare conserved features in extant genomes in the phylogeny to define potential ancestral gene adjacencies,…

Data Structures and Algorithms · Computer Science 2016-09-27 Nina Luhmann , Manuel Lafond , Annelyse Thévenin , Aïda Ouangraoua , Roland Wittler , Cedric Chauve

We study the approximation properties of convolutional architectures applied to time series modelling, which can be formulated mathematically as a functional approximation problem. In the recurrent setting, recent results reveal an…

Machine Learning · Computer Science 2021-07-21 Haotian Jiang , Zhong Li , Qianxiao Li

Variational autoencoders were proven successful in domains such as computer vision and speech processing. Their adoption for modeling user preferences is still unexplored, although recently it is starting to gain attention in the current…

Machine Learning · Computer Science 2018-11-27 Noveen Sachdeva , Giuseppe Manco , Ettore Ritacco , Vikram Pudi

The ongoing explosion of genome sequence data is transforming how we reconstruct and understand the histories of biological systems. Across biological scales, from individual cells to populations and species, trees-based models provide a…

Populations and Evolution · Quantitative Biology 2025-12-08 Yun Deng , Shing H. Zhan , Yulin Zhang , Chao Zhang , Bingjie Chen

Trees have long been used as a graphical representation of species relationships. However complex evolutionary events, such as genetic reassortments or hybrid speciations which occur commonly in viruses, bacteria and plants, do not fit into…

Populations and Evolution · Quantitative Biology 2017-07-24 Sebastien Roch , Kun-Chieh Wang

Deep generative models that learn from the distribution of natural protein sequences and structures may enable the design of new proteins with valuable functions. While the majority of today's models focus on generating either sequences or…

Biomolecules · Quantitative Biology 2024-10-03 Chentong Wang , Sarah Alamdari , Carles Domingo-Enrich , Ava Amini , Kevin K. Yang

Phylogenetic trees are simple models of evolutionary processes. They describe conditionally independent divergent evolution of taxa from common ancestors. Phylogenetic trees commonly do not have enough flexibility to adequately model all…

Populations and Evolution · Quantitative Biology 2025-11-11 Jonathan D. Mitchell , Barbara R. Holland

Time Series forecasting (univariate and multivariate) is a problem of high complexity due the different patterns that have to be detected in the input, ranging from high to low frequencies ones. In this paper we propose a new model for…

Machine Learning · Computer Science 2019-03-07 Matteo Maggiolo , Gerasimos Spanakis

The prevalent approach to sequence to sequence learning maps an input sequence to a variable length output sequence via recurrent neural networks. We introduce an architecture based entirely on convolutional neural networks. Compared to…

Computation and Language · Computer Science 2017-07-26 Jonas Gehring , Michael Auli , David Grangier , Denis Yarats , Yann N. Dauphin

Time series data arising in many applications nowadays are high-dimensional. A large number of parameters describe features of these time series. We propose a novel approach to modeling a high-dimensional time series through several…

Methodology · Statistics 2024-08-22 Arkaprava Roy , Anindya Roy , Subhashis Ghosal