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Comparing white matter (WM) connections between adults and neonates using diffusion MRI (dMRI) can advance our understanding of typical brain development and potential biomarkers for neurological disorders. However, existing WM atlases are…

Neural and Evolutionary Computing · Computer Science 2025-12-24 Wei Zhang , Yijie Li , Ruixi Zheng , Nir A. Sochen , Yuqian Chen , Leo R. Zekelman , Ofer Pasternak , Jarrett Rushmore , Yogesh Rathi , Nikos Makris , Lauren J. O'Donnell , Fan Zhang

Understanding brain connectivity has become one of the most important issues in neuroscience. But connectivity data can reflect either the functional relationships of the brain activities or the anatomical properties between brain areas.…

Neurons and Cognition · Quantitative Biology 2015-04-13 Tiago Simas , Mario Chavez , Pablo Rodriguez , Albert Diaz-Guilera

The architecture of the human connectome supports efficient communication protocols relying either on distances between brain regions or on the intensities of connections. However, none of these protocols combines information about the two…

Neurons and Cognition · Quantitative Biology 2024-10-07 Laia Barjuan , Jordi Soriano , M. Ángeles Serrano

White matter tract integrity (WMTI) can characterize brain microstructure in areas with highly aligned fiber bundles. Several WMTI biomarkers have now been validated against microscopy and provided promising results in studies of brain…

In this work we propose HAMLET, a novel tract learning algorithm, which, after training, maps raw diffusion weighted MRI directly onto an image which simultaneously indicates tract direction and tract presence. The automatic learning of…

Computer Vision and Pattern Recognition · Computer Science 2018-07-04 Marco Reisert , Volker A. Coenen , Christoph Kaller , Karl Egger , Henrik Skibbe

In this paper we show that trajectory shape analysis should be performed only after obtaining a proper representation before applying ordination methods. In fact, studying the shape of a trajectory means studying how the deformation changes…

Parallel transport of a connection in a smooth fibre bundle yields a functor from the path groupoid of the base manifold into a category that describes the fibres of the bundle. We characterize functors obtained like this by two notions we…

Differential Geometry · Mathematics 2014-08-26 Urs Schreiber , Konrad Waldorf

The goal of diffusion-weighted magnetic resonance imaging (DWI) is to infer the structural connectivity of an individual subject's brain in vivo. To statistically study the variability and differences between normal and abnormal brain…

Neurons and Cognition · Quantitative Biology 2023-03-06 Haocheng Dai , Martin Bauer , P. Thomas Fletcher , Sarang Joshi

The amygdala plays a vital role in emotional processing and exhibits structural diversity that necessitates fine-scale parcellation for a comprehensive understanding of its anatomico-functional correlations. Diffusion MRI tractography is an…

Image and Video Processing · Electrical Eng. & Systems 2023-11-28 Haolin He , Ce Zhu , Le Zhang , Yipeng Liu , Xiao Xu , Yuqian Chen , Leo Zekelman , Jarrett Rushmore , Yogesh Rathi , Nikos Makris , Lauren J. O'Donnell , Fan Zhang

Our work expands the use of capsule networks to the task of object segmentation for the first time in the literature. This is made possible via the introduction of locally-constrained routing and transformation matrix sharing, which reduces…

Image and Video Processing · Electrical Eng. & Systems 2020-12-14 Rodney LaLonde , Ziyue Xu , Ismail Irmakci , Sanjay Jain , Ulas Bagci

Individual brains vary in both anatomy and functional organization, even within a given species. Inter-individual variability is a major impediment when trying to draw generalizable conclusions from neuroimaging data collected on groups of…

Neurons and Cognition · Quantitative Biology 2023-09-28 Alexis Thual , Huy Tran , Tatiana Zemskova , Nicolas Courty , Rémi Flamary , Stanislas Dehaene , Bertrand Thirion

We have developed a novel method to describe human white matter anatomy using an approach that is both intuitive and simple to use, and which automatically extracts white matter tracts from diffusion MRI volumes. Further, our method…

Neurons and Cognition · Quantitative Biology 2015-12-24 Demian Wassermann , Makris Nikos , Yogesh Rathi , Shenton Martha , Ron Kikinis , Marek Kubicki , Carl-Fredrik Westin

Recent advances in molecular and genetic research have identified a diverse range of brain tumor sub-types, shedding light on differences in their molecular mechanisms, heterogeneity, and origins. The present study performs whole-brain…

Neurons and Cognition · Quantitative Biology 2024-07-26 Debanjali Bhattacharya , Ninad Aithal , Manish Jayswal , Neelam Sinha

Brain decoding aims to reconstruct visual perception of human subject from fMRI signals, which is crucial for understanding brain's perception mechanisms. Existing methods are confined to the single-subject paradigm due to substantial brain…

Computer Vision and Pattern Recognition · Computer Science 2025-02-10 Yuqin Dai , Zhouheng Yao , Chunfeng Song , Qihao Zheng , Weijian Mai , Kunyu Peng , Shuai Lu , Wanli Ouyang , Jian Yang , Jiamin Wu

Constructing valid and informative conformal prediction regions for multi-dimensional outputs remains a fundamental challenge. While conformal prediction provides finite-sample, distribution-free coverage guarantees, its practical…

Machine Learning · Statistics 2026-05-11 Zhenhan Fang , Aixin Tan , Jian Huang

A method is presented for the registration of MRA and 4D Flow images, with the goal of calculating blood flow properties using both modalities simultaneously. In particular, the method produces an alignment of segmentations of vessel…

Quantitative Methods · Quantitative Biology 2025-04-28 Dan Lior , Craig G. Rusin , Justin Weigand , Kristina V. Montez , Yimo Wang , Silvana Molossi , Daniel J. Penny , Charles Puelz

With the recent development of localization and tracking systems for both indoor and outdoor settings, we consider the problem of sensing, representing and analyzing human movement trajectories that we expect to gather in the near future.…

Networking and Internet Architecture · Computer Science 2017-08-31 Xiaotian Yin , Yu-Yao Lin , Chien-Chun Ni , Jiaxin Ding , Wei Han , Dengpan Zhou , Jie Gao , Xianfeng Gu

Linear models are widely used in computational neuroimaging to identify biomarkers associated with brain pathologies. However, interpreting the learned weights remains challenging, as they do not always yield clinically meaningful insights.…

Machine Learning · Computer Science 2026-04-23 Sara Petiton , Antoine Grigis , Raphaël Vock , Edouard Duchesnay

In the last years in-vivo tractography has assumed an important role in neurosciences, for both research and clinical applications such as non-invasive investigation of brain connectivity and presurgical planning in neurosurgery. In more…

Diffusion MRI tractography is an important tool for identifying and analyzing the intracranial course of cranial nerves (CNs). However, the complex environment of the skull base leads to ambiguous spatial correspondence between diffusion…

Image and Video Processing · Electrical Eng. & Systems 2024-09-23 Lei Xie , Qingrun Zeng , Huajun Zhou , Guoqiang Xie , Mingchu Li , Jiahao Huang , Jianan Cui , Hao Chen , Yuanjing Feng