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Deep generative modeling to stochastically design small molecules is an emerging technology for accelerating drug discovery and development. However, one major issue in molecular generative models is their lower frequency of drug-like…

Generative Artificial Intelligence (GenAI) tools have become increasingly prevalent in software development, offering assistance to various managerial and technical project activities. Notable examples of these tools include OpenAIs…

The integration of generative AI tools like ChatGPT into software engineering workflows opens up new opportunities to boost productivity in tasks such as unit test engineering. However, these AI-assisted workflows can also significantly…

Software Engineering · Computer Science 2025-10-14 Baris Ardic , Quentin Le Dilavrec , Andy Zaidman

The design of molecules and materials with tailored properties is challenging, as candidate molecules must satisfy multiple competing requirements that are often difficult to measure or compute. While molecular structures, produced through…

Chemical Physics · Physics 2023-02-07 Julia Westermayr , Joe Gilkes , Rhyan Barrett , Reinhard J. Maurer

The disconnect between AI-generated molecules with desirable properties and their synthetic feasibility remains a critical bottleneck in computational discovery of drugs and materials. While generative AI has accelerated the proposal of…

Chemical Physics · Physics 2025-11-25 Shuan Chen , Gunwook Nam , Alan Aspuru-Guzik , Yousung Jung

Generative Artificial Intelligence (AI) tools are increasingly deployed across social media platforms, yet their implications for user behavior and experience remain understudied, particularly regarding two critical dimensions: (1) how AI…

Human-Computer Interaction · Computer Science 2025-06-18 Anders Giovanni Møller , Daniel M. Romero , David Jurgens , Luca Maria Aiello

As a specific category of artificial intelligence (AI), generative artificial intelligence (GenAI) generates new content that resembles what is created by humans. The rapid development of GenAI systems has created a huge amount of new data…

Distributed, Parallel, and Cluster Computing · Computer Science 2023-07-11 Yun-Cheng Wang , Jintang Xue , Chengwei Wei , C. -C. Jay Kuo

The applications of generative AI have become extremely impressive, and the interplay between users and AI is even more so. Current human-AI interaction literature has taken a broad look at how humans interact with generative AI, but it…

Design inspiration is crucial for establishing the direction of a design as well as evoking feelings and conveying meanings during the conceptual design process. Many practice designers use text-based searches on platforms like Pinterest to…

Human-Computer Interaction · Computer Science 2024-07-18 Ye Wang , Nicole B. Damen , Thomas Gale , Voho Seo , Hooman Shayani

Automatic generation of graphic designs has recently received considerable attention. However, the state-of-the-art approaches are complex and rely on proprietary datasets, which creates reproducibility barriers. In this paper, we propose…

Computer Vision and Pattern Recognition · Computer Science 2024-06-13 Naoto Inoue , Kento Masui , Wataru Shimoda , Kota Yamaguchi

Generative AI has the potential to revolutionize drug discovery. Yet, despite recent advances in deep learning, existing models cannot generate molecules that satisfy all desired physicochemical properties. Herein, we describe IDOLpro, a…

Chemical Physics · Physics 2025-04-29 Amit Kadan , Kevin Ryczko , Erika Lloyd , Adrian Roitberg , Takeshi Yamazaki

Deep generative models are able to suggest new organic molecules by generating strings, trees, and graphs representing their structure. While such models allow one to generate molecules with desirable properties, they give no guarantees…

Machine Learning · Computer Science 2019-12-05 John Bradshaw , Brooks Paige , Matt J. Kusner , Marwin H. S. Segler , José Miguel Hernández-Lobato

Context: Generative Artificial Intelligence (GenAI) is transforming much of software development, yet its application in software architecture is still in its infancy, and no prior study has systematically addressed the topic. Aim: We aim…

Deep generative models have unlocked another profound realm of human creativity. By capturing and generalizing patterns within data, we have entered the epoch of all-encompassing Artificial Intelligence for General Creativity (AIGC).…

Artificial Intelligence · Computer Science 2023-12-27 Hanqun Cao , Cheng Tan , Zhangyang Gao , Yilun Xu , Guangyong Chen , Pheng-Ann Heng , Stan Z. Li

This study examines the impact of GitHub Copilot on a large sample of Copilot users (n=934,533). The analysis shows that users on average accept nearly 30% of the suggested code, leading to increased productivity. Furthermore, our research…

General Economics · Economics 2023-06-28 Thomas Dohmke , Marco Iansiti , Greg Richards

Propelled by their remarkable capabilities to generate novel and engaging content, Generative Artificial Intelligence (GenAI) technologies are disrupting traditional workflows in many industries. While prior research has examined GenAI from…

Human-Computer Interaction · Computer Science 2024-04-08 Yuan Sun , Eunchae Jang , Fenglong Ma , Ting Wang

Generative AI (GenAI) tools are radically expanding the scope and capability of automation in knowledge work such as academic research. While promising for augmenting cognition and streamlining processes, AI-assisted research tools may also…

Human-Computer Interaction · Computer Science 2025-04-22 Runlong Ye , Matthew Varona , Oliver Huang , Patrick Yung Kang Lee , Michael Liut , Carolina Nobre

Generative AI systems have entered everyday academic, professional, and personal life with remarkable speed, yet most users encounter them as mysterious artifacts rather than intelligible systems. This chapter discusses large language…

Computers and Society · Computer Science 2026-04-21 John T. Behrens

Drug discovery aims at designing novel molecules with specific desired properties for clinical trials. Over past decades, drug discovery and development have been a costly and time consuming process. Driven by big chemical data and AI, deep…

Machine Learning · Computer Science 2020-07-22 Karan Yang , Chengxi Zang , Fei Wang

The design of functional materials with desired properties is essential in driving technological advances in areas like energy storage, catalysis, and carbon capture. Generative models provide a new paradigm for materials design by directly…

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