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Not all generate-and-test search algorithms are created equal. Bayesian Optimization (BO) invests a lot of computation time to generate the candidate solution that best balances the predicted value and the uncertainty given all previous…

Neural and Evolutionary Computing · Computer Science 2020-05-11 Gongjin Lan , Jakub M. Tomczak , Diederik M. Roijers , A. E. Eiben

We propose to use Bayesian optimization (BO) to improve the efficiency of the design selection process in clinical trials. BO is a method to optimize expensive black-box functions, by using a regression as a surrogate to guide the search.…

Methodology · Statistics 2021-05-20 Jakob Richter , Tim Friede , Jörg Rahnenführer

Sequential robot manipulation tasks require finding collision-free trajectories that satisfy geometric constraints across multiple object interactions in potentially high-dimensional configuration spaces. Solving these problems in real-time…

Robotics · Computer Science 2025-10-14 Lucas Chen , Shrutheesh Raman Iyer , Zachary Kingston

Black-box zero-th order optimization is a central primitive for applications in fields as diverse as finance, physics, and engineering. In a common formulation of this problem, a designer sequentially attempts candidate solutions, receiving…

Machine Learning · Computer Science 2024-07-08 Yunchuan Zhang , Sangwoo Park , Osvaldo Simeone

Verification is a critical process in the development of engineered systems. Through verification, engineers gain confidence in the correct functionality of the system before it is deployed into operation. Traditionally, verification…

Software Engineering · Computer Science 2021-09-27 Peng Xu , Alejandro Salado , Xinwei Deng

In the context of sparse principal component detection, we bring evidence towards the existence of a statistical price to pay for computational efficiency. We measure the performance of a test by the smallest signal strength that it can…

Statistics Theory · Mathematics 2013-04-29 Quentin Berthet , Philippe Rigollet

Traditional scientific discovery relies on an iterative hypothesise-experiment-refine cycle that has driven progress for centuries, but its intuitive, ad-hoc implementation often wastes resources, yields inefficient designs, and misses…

Benefiting from the self-attention mechanism, Transformer models have attained impressive contextual comprehension capabilities for lengthy texts. The requirements of high-throughput inference arise as the large language models (LLMs)…

Hardware Architecture · Computer Science 2024-07-16 Huizheng Wang , Jiahao Fang , Xinru Tang , Zhiheng Yue , Jinxi Li , Yubin Qin , Sihan Guan , Qize Yang , Yang Wang , Chao Li , Yang Hu , Shouyi Yin

Most of the existing algorithms for approximate Bayesian computation (ABC) assume that it is feasible to simulate pseudo-data from the model at each iteration. However, the computational cost of these simulations can be prohibitive for high…

We present a detailed study of Bayesian inference workflows for pulsar timing array data with a focus on enhancing efficiency, robustness and speed through the use of normalizing flow-based nested sampling. Building on the Enterprise…

Instrumentation and Methods for Astrophysics · Physics 2025-11-05 Eleonora Villa , Golam Mohiuddin Shaifullah , Andrea Possenti , Carmelita Carbone

Bayesian optimization (BO) is a powerful technology for optimizing noisy expensive-to-evaluate black-box functions, with a broad range of real-world applications in science, engineering, economics, manufacturing, and beyond. In this paper,…

Machine Learning · Computer Science 2024-01-30 Joel A. Paulson , Calvin Tsay

As brain-computer interfacing (BCI) systems transition from assistive technology to more diverse applications, their speed, reliability, and user experience become increasingly important. Dynamic stopping methods enhance BCI system speed by…

Human-Computer Interaction · Computer Science 2024-06-18 Sara Ahmadi , Peter Desain , Jordy Thielen

Processing-in-memory (PIM) has shown extraordinary potential in accelerating neural networks. To evaluate the performance of PIM accelerators, we present an ISA-based simulation framework including a dedicated ISA targeting neural networks…

Hardware Architecture · Computer Science 2024-02-29 Xinyu Wang , Xiaotian Sun , Yinhe Han , Xiaoming Chen

Controller tuning and parameter optimization are crucial in system design to improve closed-loop system performance. Bayesian optimization has been established as an efficient model-free controller tuning and adaptation method. However,…

Systems and Control · Electrical Eng. & Systems 2024-04-24 Christopher König , Raamadaas Krishnadas , Efe C. Balta , Alisa Rupenyan

This paper presents a method called sampling-computation-optimization (SCO) to design batch Bayesian optimization. SCO does not construct new high-dimensional acquisition functions but samples from the existing one-site acquisition function…

Optimization and Control · Mathematics 2022-02-22 Kai Jia , Xiaojun Duan , Zhengming Wang , Liang Yan

Principal Component Analysis (PCA) has been widely used for dimensionality reduction and feature extraction. Robust PCA (RPCA), under different robust distance metrics, such as l1-norm and l2, p-norm, can deal with noise or outliers to some…

Machine Learning · Computer Science 2021-06-29 Zhao Kang , Hongfei Liu , Jiangxin Li , Xiaofeng Zhu , Ling Tian

Clinical trials are essential to drug development but time-consuming, costly, and prone to failure. Accurate trial outcome prediction based on historical trial data promises better trial investment decisions and more trial success. Existing…

Machine Learning · Computer Science 2023-04-12 Zifeng Wang , Cao Xiao , Jimeng Sun

This paper proposes a new logic optimization paradigm based on circuit simulation, which reduces the need for Boolean computations such as SAT-solving or constructing BDDs. The paper develops a Boolean resubstitution framework to…

Logic in Computer Science · Computer Science 2020-07-07 Siang-Yun Lee , Heinz Riener , Alan Mishchenko , Robert K. Brayton , Giovanni De Micheli

Dynamic sparsity, where the sparsity patterns are unknown until runtime, poses a significant challenge to deep learning. The state-of-the-art sparsity-aware deep learning solutions are restricted to pre-defined, static sparsity patterns due…

Recently, large models, such as Vision Transformer and BERT, have garnered significant attention due to their exceptional performance. However, their extensive computational requirements lead to considerable power and hardware resource…

Hardware Architecture · Computer Science 2025-01-15 Zhengke Li , Wendong Mao , Siyu Zhang , Qiwei Dong , Zhongfeng Wang
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