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Segmentation algorithms are prone to make topological errors on fine-scale structures, e.g., broken connections. We propose a novel method that learns to segment with correct topology. In particular, we design a continuous-valued loss…

Computer Vision and Pattern Recognition · Computer Science 2019-06-18 Xiaoling Hu , Li Fuxin , Dimitris Samaras , Chao Chen

Topological accuracy in medical image segmentation is a highly important property for downstream applications such as network analysis and flow modeling in vessels or cell counting. Recently, significant methodological advancements have…

Image and Video Processing · Electrical Eng. & Systems 2024-10-10 Alexander H. Berger , Nico Stucki , Laurin Lux , Vincent Buergin , Suprosanna Shit , Anna Banaszak , Daniel Rueckert , Ulrich Bauer , Johannes C. Paetzold

Blood vessel segmentation and -tracing are essential tasks in many medical imaging applications. Although numerous methods exist, the prevailing segment-then-fix paradigm is fundamentally limited regarding its suitability for modeling the…

Computer Vision and Pattern Recognition · Computer Science 2026-05-04 Rajalakshmi Palaniappan , Christoph Karg , Nemesio Navarro-Arambula , Peter Hirsch , Kristin Kraeker , Lisa Mais , Dagmar Kainmueller

Accurate segmentation of tubular, network-like structures, such as vessels, neurons, or roads, is relevant to many fields of research. For such structures, the topology is their most important characteristic; particularly preserving…

Computer Vision and Pattern Recognition · Computer Science 2022-07-18 Suprosanna Shit , Johannes C. Paetzold , Anjany Sekuboyina , Ivan Ezhov , Alexander Unger , Andrey Zhylka , Josien P. W. Pluim , Ulrich Bauer , Bjoern H. Menze

Image segmentation is a largely researched field where neural networks find vast applications in many facets of technology. Some of the most popular approaches to train segmentation networks employ loss functions optimizing pixel-overlap,…

Computer Vision and Pattern Recognition · Computer Science 2022-11-29 Nico Stucki , Johannes C. Paetzold , Suprosanna Shit , Bjoern Menze , Ulrich Bauer

Topological correctness is critical for segmentation of tubular structures, which pervade in biomedical images. Existing topological segmentation loss functions are primarily based on the persistent homology of the image. They match the…

Computer Vision and Pattern Recognition · Computer Science 2025-10-29 Bo Wen , Haochen Zhang , Dirk-Uwe G. Bartsch , William R. Freeman , Truong Q. Nguyen , Cheolhong An

Reconstructing Portal Vein and Hepatic Vein trees from contrast enhanced abdominal CT scans is a prerequisite for preoperative liver surgery simulation. Existing deep learning based methods treat vascular tree reconstruction as a semantic…

Computer Vision and Pattern Recognition · Computer Science 2020-09-21 Deepak Keshwani , Yoshiro Kitamura , Satoshi Ihara , Satoshi Iizuka , Edgar Simo-Serra

Segmentation networks are not explicitly imposed to learn global invariants of an image, such as the shape of an object and the geometry between multiple objects, when they are trained with a standard loss function. On the other hand,…

Image and Video Processing · Electrical Eng. & Systems 2026-01-21 Seher Ozcelik , Sinan Unver , Ilke Ali Gurses , Rustu Turkay , Cigdem Gunduz-Demir

Many studies regarding the vasculature of biological tissues involve the segmentation of the blood vessels in a sample followed by the creation of a graph structure to model the vasculature. The graph is then used to extract relevant…

Computer Vision and Pattern Recognition · Computer Science 2024-06-21 João Pedro Parella , Matheus Viana da Silva , Cesar Henrique Comin

Topological correctness plays a critical role in many image segmentation tasks, yet most networks are trained using pixel-wise loss functions, such as Dice, neglecting topological accuracy. Existing topology-aware methods often lack robust…

Computer Vision and Pattern Recognition · Computer Science 2025-04-21 Laurin Lux , Alexander H. Berger , Alexander Weers , Nico Stucki , Daniel Rueckert , Ulrich Bauer , Johannes C. Paetzold

The precise delineation of blood vessels in medical images is critical for many clinical applications, including pathology detection and surgical planning. However, fully-automated vascular segmentation is challenging because of the…

Image and Video Processing · Electrical Eng. & Systems 2024-09-20 Amine Sadikine , Bogdan Badic , Enzo Ferrante , Vincent Noblet , Pascal Ballet , Dimitris Visvikis , Pierre-Henri Conze

Although the preservation of shape continuity and physiological anatomy is a natural assumption in the segmentation of medical images, it is often neglected by deep learning methods that mostly aim for the statistical modeling of input data…

Computer Vision and Pattern Recognition · Computer Science 2023-05-01 Yousef Yeganeh , Azade Farshad , Goktug Guevercin , Amr Abu-zer , Rui Xiao , Yongjian Tang , Ehsan Adeli , Nassir Navab

Tree-like structures, such as blood vessels, often express complexity at very fine scales, requiring high-resolution grids to adequately describe their shape. Such sparse morphology can alternately be represented by locations of centreline…

Computer Vision and Pattern Recognition · Computer Science 2018-11-09 Kerry Halupka , Rahil Garnavi , Stephen Moore

Accurate segmentation of blood vessels is essential for various clinical assessments and postoperative analyses. However, the inherent challenges of vascular imaging, such as sparsity, fine granularity, low contrast, data distribution…

Image and Video Processing · Electrical Eng. & Systems 2024-11-26 Dongning Song , Weijian Huang , Jiarun Liu , Md Jahidul Islam , Hao Yang , Shanshan Wang

Segmenting multiple objects (e.g., organs) in medical images often requires an understanding of their topology, which simultaneously quantifies the shape of the objects and their positions relative to each other. This understanding is…

Image and Video Processing · Electrical Eng. & Systems 2024-08-16 Mehmet Bahadir Erden , Sinan Unver , Ilke Ali Gurses , Rustu Turkay , Cigdem Gunduz-Demir

Delineating 3D blood vessels is essential for clinical diagnosis and treatment, however, is challenging due to complex structure variations and varied imaging conditions. Supervised deep learning has demonstrated its superior capacity in…

Image and Video Processing · Electrical Eng. & Systems 2023-02-08 Huai Chen , Xiuying Wang , Lisheng Wang

We introduce a method for training neural networks to perform image or volume segmentation in which prior knowledge about the topology of the segmented object can be explicitly provided and then incorporated into the training process. By…

Computer Vision and Pattern Recognition · Computer Science 2020-09-21 James R. Clough , Nicholas Byrne , Ilkay Oksuz , Veronika A. Zimmer , Julia A. Schnabel , Andrew P. King

Topological consistency plays a crucial role in the task of boundary segmentation for reticular images, such as cell membrane segmentation in neuron electron microscopic images, grain boundary segmentation in material microscopic images and…

Computer Vision and Pattern Recognition · Computer Science 2026-05-27 Chuni Liu , Boyuan Ma , Xiaojuan Ban , Yujie Xie , Hao Wang , Weihua Xue , Jingchao Ma , Ke Xu

Medical image segmentation, which aims to automatically extract anatomical or pathological structures, plays a key role in computer-aided diagnosis and disease analysis. Despite the problem has been widely studied, existing methods are…

Image and Video Processing · Electrical Eng. & Systems 2022-03-01 Han Zhang , Lok Ming Lui

Accurately segmenting thin tubular structures, such as vessels, nerves, roads or concrete cracks, is a crucial task in computer vision. Standard deep learning-based segmentation loss functions, such as Dice or Cross-Entropy, focus on…

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