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Datasets with missing values are very common in real world applications. GAIN, a recently proposed deep generative model for missing data imputation, has been proved to outperform many state-of-the-art methods. But GAIN only uses a…

Machine Learning · Computer Science 2021-04-07 Yufeng Wang , Dan Li , Xiang Li , Min Yang

A key challenge in learning from multimodal biological data is missing modalities, where data from one or more modalities are absent for some patients. Existing approaches either exclude patients with missing modalities, impute missing…

Machine Learning · Computer Science 2026-05-19 Sina Tabakhi , Chen , Chen , Haiping Lu

Data collected in clinical trials are often composed of multiple types of variables. For example, laboratory measurements and vital signs are longitudinal data of continuous or categorical variables, adverse events may be recurrent events,…

Methodology · Statistics 2023-01-12 Tuo Wang , Rachel Zilinskas , Ying Li , Yongming Qu

Multi-modal Learning has attracted widespread attention in medical image analysis. Using multi-modal data, whole slide images (WSIs) and clinical information, can improve the performance of deep learning models in the diagnosis of axillary…

Image and Video Processing · Electrical Eng. & Systems 2024-01-04 Shichuan Zhang , Sunyi Zheng , Zhongyi Shui , Honglin Li , Lin Yang

In real world clinical environments, training and applying deep learning models on multi-modal medical imaging data often struggles with partially incomplete data. Standard approaches either discard missing samples, require imputation or…

Computer Vision and Pattern Recognition · Computer Science 2025-09-16 Christoph Fürböck , Paul Weiser , Branko Mitic , Philipp Seeböck , Thomas Helbich , Georg Langs

In an era when big data are becoming the norm, there is less concern with the quantity but more with the quality and completeness of the data. In many disciplines, data are collected from heterogeneous sources, resulting in multi-view or…

Computer Vision and Pattern Recognition · Computer Science 2017-11-02 Chao Shang , Aaron Palmer , Jiangwen Sun , Ko-Shin Chen , Jin Lu , Jinbo Bi

Integrating cross-department multi-modal data (e.g., radiological, pathological, genomic, and clinical data) is ubiquitous in brain cancer diagnosis and survival prediction. To date, such an integration is typically conducted by human…

Machine Learning · Computer Science 2022-07-20 Can Cui , Han Liu , Quan Liu , Ruining Deng , Zuhayr Asad , Yaohong WangShilin Zhao , Haichun Yang , Bennett A. Landman , Yuankai Huo

Recent advancements in the acquisition of various brain data sources have created new opportunities for integrating multimodal brain data to assist in early detection of complex brain disorders. However, current data integration approaches…

Image and Video Processing · Electrical Eng. & Systems 2023-05-26 Reza Shirkavand , Liang Zhan , Heng Huang , Li Shen , Paul M. Thompson

Accurate prediction of mortality in nasopharyngeal carcinoma (NPC), a complex malignancy particularly challenging in advanced stages, is crucial for optimizing treatment strategies and improving patient outcomes. However, this predictive…

Machine Learning · Computer Science 2024-10-25 Yejing Huo , Guoheng Huang , Lianglun Cheng , Jianbin He , Xuhang Chen , Xiaochen Yuan , Guo Zhong , Chi-Man Pun

Many real-world datasets contain missing entries and mixed data types including categorical and ordered (e.g. continuous and ordinal) variables. Imputing the missing entries is necessary, since many data analysis pipelines require complete…

Methodology · Statistics 2022-10-14 Yuxuan Zhao , Alex Townsend , Madeleine Udell

Accurate survival prediction in Non-Small Cell Lung Cancer (NSCLC) requires integrating clinical, radiological, and histopathological data. Multimodal Deep Learning (MDL) can improve precision prognosis, but small cohorts and missing…

Missing data imputation can help improve the performance of prediction models in situations where missing data hide useful information. This paper compares methods for imputing missing categorical data for supervised classification tasks.…

Machine Learning · Statistics 2020-08-11 Jason Poulos , Rafael Valle

The use of machine learning (ML) for cancer staging through medical image analysis has gained substantial interest across medical disciplines. When accompanied by the innovative federated learning (FL) framework, ML techniques can further…

Machine Learning · Computer Science 2024-10-10 Kasra Borazjani , Naji Khosravan , Leslie Ying , Seyyedali Hosseinalipour

Deep generative models with latent variables have been used lately to learn joint representations and generative processes from multi-modal data. These two learning mechanisms can, however, conflict with each other and representations can…

Machine Learning · Computer Science 2023-01-24 Rogelio A. Mancisidor , Michael Kampffmeyer , Kjersti Aas , Robert Jenssen

Radiologists must utilize multiple modal images for tumor segmentation and diagnosis due to the limitations of medical imaging and the diversity of tumor signals. This leads to the development of multimodal learning in segmentation.…

Computer Vision and Pattern Recognition · Computer Science 2024-07-11 Chuyun Shen , Wenhao Li , Haoqing Chen , Xiaoling Wang , Fengping Zhu , Yuxin Li , Xiangfeng Wang , Bo Jin

Methods to handle missing data have been extensively explored in the context of estimation and descriptive studies, with multiple imputation being the most widely used method in clinical research. However, in the context of clinical risk…

Methodology · Statistics 2024-11-25 Junhui Mi , Rahul D. Tendulkar , Sarah M. C. Sittenfeld , Sujata Patil , Emily C. Zabor

Ophthalmologists typically require multimodal data sources to improve diagnostic accuracy in clinical decisions. However, due to medical device shortages, low-quality data and data privacy concerns, missing data modalities are common in…

Computer Vision and Pattern Recognition · Computer Science 2025-02-18 Chengzhi Liu , Zile Huang , Zhe Chen , Feilong Tang , Yu Tian , Zhongxing Xu , Zihong Luo , Yalin Zheng , Yanda Meng

Data availability plays a critical role for the performance of deep learning systems. This challenge is especially acute within the medical image domain, particularly when pathologies are involved, due to two factors: 1) limited number of…

Computer Vision and Pattern Recognition · Computer Science 2018-06-12 Dakai Jin , Ziyue Xu , Youbao Tang , Adam P. Harrison , Daniel J. Mollura

Clinical data elements (CDEs) (e.g., age, smoking history), blood markers and chest computed tomography (CT) structural features have been regarded as effective means for assessing lung cancer risk. These independent variables can provide…

Image and Video Processing · Electrical Eng. & Systems 2021-02-11 Riqiang Gao , Yucheng Tang , Kaiwen Xu , Michael N. Kammer , Sanja L. Antic , Steve Deppen , Kim L. Sandler , Pierre P. Massion , Yuankai Huo , Bennett A. Landman