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Multiple organ failure (MOF) is a severe syndrome with a high mortality rate among Intensive Care Unit (ICU) patients. Early and precise detection is critical for clinicians to make timely decisions. An essential challenge in applying…

Machine Learning · Computer Science 2021-06-23 Xinlu Zhang , Yun Zhao , Rachael Callcut , Linda Petzold

Combining multiple modalities carrying complementary information through multimodal learning (MML) has shown considerable benefits for diagnosing multiple pathologies. However, the robustness of multimodal models to missing modalities is…

Machine Learning · Computer Science 2024-07-31 Hava Chaptoukaev , Vincenzo Marcianó , Francesco Galati , Maria A. Zuluaga

International comparisons of hierarchical time series data sets based on survey data, such as annual country-level estimates of school enrollment rates, can suffer from large amounts of missing data due to differing coverage of surveys…

Methodology · Statistics 2025-03-31 Daphne H. Liu , Adrian E. Raftery

Missing data is a major challenge in clinical research. In electronic medical records, often a large fraction of the values in laboratory tests and vital signs are missing. The missingness can lead to biased estimates and limit our ability…

Machine Learning · Computer Science 2023-04-18 Omer Noy , Ron Shamir

Although approaches for handling missing data from longitudinal studies are well-developed when the patterns of missingness are monotone, fewer methods are available for non-monotone missingness. Moreover, the conventional missing at random…

Methodology · Statistics 2023-02-28 Boyu Ren , Stuart R. Lipsitz , Roger D. Weiss , Garrett M. Fitzmaurice

Missing values exist in nearly all clinical studies because data for a variable or question are not collected or not available. Inadequate handling of missing values can lead to biased results and loss of statistical power in analysis.…

Machine Learning · Computer Science 2021-03-04 Narges Pourshahrokhi , Samaneh Kouchaki , Kord M. Kober , Christine Miaskowski , Payam Barnaghi

Missing data is unavoidable in longitudinal clinical trials, and outcomes are not always normally distributed. In the presence of outliers or heavy-tailed distributions, the conventional multiple imputation with the mixed model with…

Methodology · Statistics 2022-03-22 Siyi Liu , Yilong Zhang , Gregory T Golm , Guanghan , Liu , Shu Yang

Imputation of missing data is a common application in various classification problems where the feature training matrix has missingness. A widely used solution to this imputation problem is based on the lazy learning technique, $k$-nearest…

Machine Learning · Statistics 2020-02-26 Arkopal Choudhury , Michael R. Kosorok

Learning multimodal representations from medical images and other data sources can provide richer information for decision-making. While various multimodal models have been developed for this, they overlook learning features that are both…

Computer Vision and Pattern Recognition · Computer Science 2026-03-03 Boyu Chen , Weiye Bao , Junjie Liu , Michael Shen , Bo Peng , Paul Taylor , Zhu Li , Mengyue Yang

Missing data has a ubiquitous presence in real-life applications of machine learning techniques. Imputation methods are algorithms conceived for restoring missing values in the data, based on other entries in the database. The choice of the…

Machine Learning · Computer Science 2017-08-16 Unai Garciarena , Roberto Santana , Alexander Mendiburu

State-of-the-art deep learning algorithms yield remarkable results in many visual recognition tasks. However, they still fail to provide satisfactory results in scarce data regimes. To a certain extent this lack of data can be compensated…

Computer Vision and Pattern Recognition · Computer Science 2018-11-26 Frederik Pahde , Oleksiy Ostapenko , Patrick Jähnichen , Tassilo Klein , Moin Nabi

We formalize the problem of learning interdomain correspondences in the absence of paired data as Bayesian inference in a latent variable model (LVM), where one seeks the underlying hidden representations of entities from one domain as…

Machine Learning · Statistics 2018-08-27 Louis C. Tiao , Edwin V. Bonilla , Fabio Ramos

The target of image-text clustering (ITC) is to find correct clusters by integrating complementary and consistent information of multi-modalities for these heterogeneous samples. However, the majority of current studies analyse ITC on the…

Artificial Intelligence · Computer Science 2022-12-01 Dongjin Guo , Xiaoming Su , Jiatai Wang , Limin Liu , Zhiyong Pei , Zhiwei Xu

We present and compare multiple imputation methods for multilevel continuous and binary data where variables are systematically and sporadically missing. The methods are compared from a theoretical point of view and through an extensive…

Lung cancer has a high rate of recurrence in early-stage patients. Predicting the post-surgical recurrence in lung cancer patients has traditionally been approached using single modality information of genomics or radiology images. We…

Image and Video Processing · Electrical Eng. & Systems 2020-02-07 Vaishnavi Subramanian , Minh N. Do , Tanveer Syeda-Mahmood

Missing data is a challenge when developing, validating and deploying clinical prediction models (CPMs). Traditionally, decisions concerning missing data handling during CPM development and validation havent accounted for whether…

Modern datasets commonly feature both substantial missingness and many variables of mixed data types, which present significant challenges for estimation and inference. Complete case analysis, which proceeds using only the observations with…

Methodology · Statistics 2023-04-10 Joseph Feldman , Daniel R. Kowal

When estimating heterogeneous treatment effects, missing outcome data can complicate treatment effect estimation, causing certain subgroups of the population to be poorly represented. In this work, we discuss this commonly overlooked…

Machine Learning · Statistics 2025-04-15 Matthew Pryce , Karla Diaz-Ordaz , Ruth H. Keogh , Stijn Vansteelandt

Brain tumor segmentation is often based on multiple magnetic resonance imaging (MRI). However, in clinical practice, certain modalities of MRI may be missing, which presents a more difficult scenario. To cope with this challenge, Knowledge…

Computer Vision and Pattern Recognition · Computer Science 2024-08-20 Tianyi Liu , Zhaorui Tan , Muyin Chen , Xi Yang , Haochuan Jiang , Kaizhu Huang

Microbiome data analysis is essential for understanding host health and disease, yet its inherent sparsity and noise pose major challenges for accurate imputation, hindering downstream tasks such as biomarker discovery. Existing imputation…

Machine Learning · Computer Science 2025-08-01 Rabeya Tus Sadia , Qiang Cheng
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