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Individualized treatment recommendation (ITR) is an important analytic framework for precision medicine. The goal is to assign proper treatments to patients based on their individual characteristics. From the machine learning perspective,…

Machine Learning · Statistics 2020-04-07 Haomiao Meng , Ying-Qi Zhao , Haoda Fu , Xingye Qiao

In this technical note, we introduce and analyze AWNN: an adaptively weighted nearest neighbor method for performing matrix completion. Nearest neighbor (NN) methods are widely used in missing data problems across multiple disciplines such…

Machine Learning · Statistics 2025-05-15 Tathagata Sadhukhan , Manit Paul , Raaz Dwivedi

Organ transplants can improve the life expectancy and quality of life for the recipient but carries the risk of serious post-operative complications, such as septic shock and organ rejection. The probability of a successful transplant…

Machine Learning · Computer Science 2016-11-15 Jinsung Yoon , Ahmed M. Alaa , Martin Cadeiras , Mihaela van der Schaar

To promote precision medicine, individualized treatment regimes (ITRs) are crucial for optimizing the expected clinical outcome based on patient-specific characteristics. However, existing ITR research has primarily focused on scenarios…

Methodology · Statistics 2024-02-20 Chang Wang , Lu Wang

Imputing incomplete medical tests and predicting patient outcomes are crucial for guiding the decision making for therapy, such as after an Achilles Tendon Rupture (ATR). We formulate the problem of data imputation and prediction for ATR…

Machine Learning · Computer Science 2016-12-09 An Qu , Cheng Zhang , Paul Ackermann , Hedvig Kjellström

Research on recommender systems algorithms, like other areas of applied machine learning, is largely dominated by efforts to improve the state-of-the-art, typically in terms of accuracy measures. Several recent research works however…

Information Retrieval · Computer Science 2022-05-16 Vito Walter Anelli , Alejandro Bellogín , Tommaso Di Noia , Dietmar Jannach , Claudio Pomo

The comparison of different medical treatments from observational studies or across different clinical studies is often biased by confounding factors such as systematic differences in patient demographics or in the inclusion criteria for…

Methodology · Statistics 2025-05-15 Ekkehard Glimm , Lillian Yau

We propose a simulation-optimization-based methodology to improve the way that organ transplant offers are made to potential recipients. Our policy can be applied to all types of organs, is implemented starting at the local level, is…

Medical Physics · Physics 2022-12-01 Ignacio Erazo , David Goldsman , Pinar Keskinocak , Joel Sokol

The profile-based matching problem is the problem of finding a matching that optimizes profile from an instance $(G, r, \langle u_1, \dots, u_r \rangle)$, where $G$ is a bipartite graph $(A \cup B, E)$, $r$ is the number of utility…

Discrete Mathematics · Computer Science 2025-07-02 Seongbeom Park

Kidney transplantation is the preferred treatment for end-stage renal disease, yet the scarcity of donors and inefficiencies in allocation systems create major bottlenecks, resulting in prolonged wait times and alarming mortality rates.…

Computer Science and Game Theory · Computer Science 2024-10-15 Sean Berry , Berk Gorgulu , Sait Tunc , Mucahit Cevik , Matthew J Ellis

Decisions about managing patients on the heart transplant waitlist are currently made by committees of doctors who consider multiple factors, but the process remains largely ad-hoc. With the growing volume of longitudinal patient, donor,…

Applications · Statistics 2025-07-11 Yingtao Luo , Reza Skandari , Carlos Martinez , Arman Kilic , Rema Padman

The efficient and fair allocation of limited resources is a classical problem in economics and computer science. In kidney exchanges, a central market maker allocates living kidney donors to patients in need of an organ. Patients and donors…

Artificial Intelligence · Computer Science 2020-05-21 Rachel Freedman , Jana Schaich Borg , Walter Sinnott-Armstrong , John P. Dickerson , Vincent Conitzer

Top-N recommender systems have been investigated widely both in industry and academia. However, the recommendation quality is far from satisfactory. In this paper, we propose a simple yet promising algorithm. We fill the user-item matrix…

Information Retrieval · Computer Science 2016-01-20 Zhao Kang , Chong Peng , Qiang Cheng

Personalized optimal decision making, finding the optimal decision rule (ODR) based on individual characteristics, has attracted increasing attention recently in many fields, such as education, economics, and medicine. Current ODR methods…

Methodology · Statistics 2021-04-22 Hengrui Cai , Rui Song , Wenbin Lu

The importance of accurate recommender systems has been widely recognized by academia and industry. However, the recommendation quality is still rather low. Recently, a linear sparse and low-rank representation of the user-item matrix has…

Information Retrieval · Computer Science 2016-02-29 Zhao Kang , Qiang Cheng

AI algorithms increasingly make decisions that impact entire groups of humans. Since humans tend to hold varying and even conflicting preferences, AI algorithms responsible for making decisions on behalf of such groups encounter the problem…

Artificial Intelligence · Computer Science 2020-06-18 Rachel Freedman

Inverse treatment planning in radiation therapy is formulated as optimization problems. The objective function and constraints consist of multiple terms designed for different clinical and practical considerations. Weighting factors of…

Well-calibrated predictions of user preferences are essential for many applications. Since recommender systems typically select the top-N items for users, calibration for those top-N items, rather than for all items, is important. We show…

Information Retrieval · Computer Science 2024-08-22 Masahiro Sato

Matrix factorization is a widely used approach for top-N recommendation and collaborative filtering. When implemented on implicit feedback data (such as clicks), a common heuristic is to upweight the observed interactions. This strategy has…

Information Retrieval · Computer Science 2025-10-14 Alex Ayoub , Samuel Robertson , Dawen Liang , Harald Steck , Nathan Kallus

Relatives and friends of an end-stage renal disease patient who offer to donate a kidney are often found to be incompatible with their intended recipients. Kidney paired donation matches one patient and his incompatible donor with another…

Computer Science and Game Theory · Computer Science 2017-10-24 Sommer Gentry , Michal Mankowski , T. S. Michael , Dorry Segev
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