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This paper presents new results about the optimization based generation of chemical reaction networks (CRNs) of higher deficiency. Firstly, it is shown that the graph structure of the realization containing the maximal number of reactions…

Molecular Networks · Quantitative Biology 2011-03-23 Gabor Szederkenyi , Katalin M. Hangos , Tamas Peni

In distributed optimization for large-scale learning, a major performance limitation comes from the communications between the different entities. When computations are performed by workers on local data while a coordinator machine…

Optimization and Control · Mathematics 2020-06-26 Dmitry Grishchenko , Franck Iutzeler , Jérôme Malick , Massih-Reza Amini

Small random perturbations may have a dramatic impact on the long time evolution of dynamical systems, and large deviation theory is often the right theoretical framework to understand these effects. At the core of the theory lies the…

Numerical Analysis · Mathematics 2017-10-11 Tobias Grafke , Tobias Schaefer , Eric Vanden-Eijnden

Canonical Correlation Analysis (CCA) is a multivariate technique that takes two datasets and forms the most highly correlated possible pairs of linear combinations between them. Each subsequent pair of linear combinations is orthogonal to…

Methodology · Statistics 2015-12-22 Jacob Coleman , Joseph Replogle , Gabriel Chandler , Johanna Hardin

Canonical correlation analysis (CCA) is a multivariate statistical method which describes the associations between two sets of variables. The objective is to find linear combinations of the variables in each data set having maximal…

Methodology · Statistics 2015-01-07 Ines Wilms , Christophe Croux

Dimensionality reduction (DR) methods have been commonly used as a principled way to understand the high-dimensional data such as facial images. In this paper, we propose a new supervised DR method called Optimized Projection for Sparse…

Computer Vision and Pattern Recognition · Computer Science 2015-02-03 Can-Yi Lu , De-Shuang Huang

Reservoir Computing (RC) is a well-known strategy for designing Recurrent Neural Networks featured by striking efficiency of training. The crucial aspect of RC is to properly instantiate the hidden recurrent layer that serves as dynamical…

Machine Learning · Computer Science 2020-06-05 Claudio Gallicchio

Regular firing neurons can be seen as oscillators. The phase-response curve (PRC) describes how such neurons will respond to small excitatory perturbations. Knowledge of the PRC is important as it is associated to the excitability type of…

Neurons and Cognition · Quantitative Biology 2010-01-05 Benjamin Torben-Nielsen , Marylka Uusisaari , Klaus M. Stiefel

Coordinate descent algorithms solve optimization problems by successively performing approximate minimization along coordinate directions or coordinate hyperplanes. They have been used in applications for many years, and their popularity…

Optimization and Control · Mathematics 2015-02-18 Stephen J. Wright

Branch and bound algorithms have been developed for reliability analysis of coherent systems. They exhibit a set of advantages; in particular, they can find a computationally efficient representation of a system failure or survival event,…

Optimization and Control · Mathematics 2024-10-31 Ji-Eun Byun , Hyeuk Ryu , Daniel Straub

Sparse regression is frequently employed in diverse scientific settings as a feature selection method. A pervasive aspect of scientific data that hampers both feature selection and estimation is the presence of strong correlations between…

Methodology · Statistics 2021-03-25 Ankit Kumar , Sharmodeep Bhattacharyya , Kristofer Bouchard

This paper considers risk-sensitive model predictive control for stochastic systems with a decision-dependent distribution. This class of systems is commonly found in human-robot interaction scenarios. We derive computationally tractable…

Optimization and Control · Mathematics 2025-06-02 Renzi Wang , Mathijs Schuurmans , Panagiotis Patrinos

The importance of feedback control is being increasingly appreciated in quantum physics and applications. This paper describes the use of optimal control methods in the design of quantum feedback control systems, and in particular the paper…

Quantum Physics · Physics 2009-11-10 M. R. James

Corrupted data sets containing noisy or missing observations are prevalent in various contemporary applications such as economics, finance and bioinformatics. Despite the recent methodological and algorithmic advances in high-dimensional…

Methodology · Statistics 2020-05-12 J. Wu , Z. Zheng , Y. Li , Y. Zhang

The state-of-the-art methods for solving optimization problems in big dimensions are variants of randomized coordinate descent (RCD). In this paper we introduce a fundamentally new type of acceleration strategy for RCD based on the…

Optimization and Control · Mathematics 2018-02-13 Dmitry Kovalev , Eduard Gorbunov , Elnur Gasanov , Peter Richtárik

In this paper we present a method to approximate optimal feedback controls for stochastic reaction-diffusion equations. We derive two approximation results providing the theoretical foundation of our approach and allowing for explicit error…

Optimization and Control · Mathematics 2023-08-14 Wilhelm Stannat , Alexander Vogler

Both neurophysiological and psychophysical experiments have pointed out the crucial role of recurrent and feedback connections to process context-dependent information in the early visual cortex. While numerous models have accounted for…

Computer Vision and Pattern Recognition · Computer Science 2019-10-18 Victor Boutin , Angelo Franciosini , Frederic Chavane , Franck Ruffier , Laurent Perrinet

Lateral predictive coding (LPC) is a simple theoretical framework to appreciate feature detection in biological neural circuits. Recent theoretical work [Huang et al., Phys.Rev.E 112, 034304 (2025)] has successfully constructed optimal LPC…

Neurons and Cognition · Quantitative Biology 2026-04-23 Guanghui Cai , Zhen-Ye Huang , Weikang Wang , Hai-Jun Zhou

Reservoir computing (RC) represents a class of state-space models (SSMs) characterized by a fixed state transition mechanism (the reservoir) and a flexible readout layer that maps from the state space. It is a paradigm of computational…

Machine Learning · Computer Science 2025-04-17 Pradeep Singh , Ashutosh Kumar , Sutirtha Ghosh , Hrishit B P , Balasubramanian Raman

The method developed by Michaelis and Menten was foundational in the development of our understanding of biochemical reaction kinetics. Extended models of metabolism encapsulated by reaction rate theory, stochastic reaction models, and…

Molecular Networks · Quantitative Biology 2024-01-11 Tjeerd V. olde Scheper
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