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Multi-task learning is frequently used to model a set of related response variables from the same set of features, improving predictive performance and modeling accuracy relative to methods that handle each response variable separately.…

Methodology · Statistics 2023-08-11 Snigdha Panigrahi , Natasha Stewart , Chandra Sekhar Sripada , Elizaveta Levina

We study sparse group Lasso for high-dimensional double sparse linear regression, where the parameter of interest is simultaneously element-wise and group-wise sparse. This problem is an important instance of the simultaneously structured…

Statistics Theory · Mathematics 2022-05-10 T. Tony Cai , Anru R. Zhang , Yuchen Zhou

Functional brain networks are well described and estimated from data with Gaussian Graphical Models (GGMs), e.g. using sparse inverse covariance estimators. Comparing functional connectivity of subjects in two populations calls for…

Machine Learning · Statistics 2016-11-21 Eugene Belilovsky , Gaël Varoquaux , Matthew B. Blaschko

We develop a Bayesian tree ensemble model to estimate heterogeneous treatment effects in censored survival data with high-dimensional covariates. Instead of imposing sparsity through the tree structure, we place a horseshoe prior directly…

Methodology · Statistics 2026-05-08 Tijn Jacobs , Wessel N. van Wieringen , Stéphanie L. van der Pas

Many problems require the selection of a subset of variables from a full set of optimization variables. The computational complexity of an exhaustive search over all possible subsets of variables is, however, prohibitively expensive,…

Signal Processing · Electrical Eng. & Systems 2022-01-27 Jonathan Dan , Simon Geirnaert , Alexander Bertrand

In large-scale epidemiological studies, statistical inference is often complicated by high-dimensional covariates under stratified sampling designs for failure times. Variable selection methods developed for full cohort data do not extend…

Methodology · Statistics 2025-07-22 Ying Chen , Chuan-Fa Tang , Sy Han Chiou , Min Chen

Consider the normal linear regression setup when the number of covariates p is much larger than the sample size n, and the covariates form correlated groups. The response variable y is not related to an entire group of covariates in all or…

Methodology · Statistics 2023-09-06 Pranay Agarwal , Subhajit Dutta , Minerva Mukhopadhyay

We propose a sequential learning policy for noisy discrete global optimization and ranking and selection (R\&S) problems with high dimensional sparse belief functions, where there are hundreds or even thousands of features, but only a small…

Machine Learning · Statistics 2015-03-20 Yan Li , Han Liu , Warren Powell

Identifying co-varying causal elements in very high dimensional feature space with internal structures, e.g., a space with as many as millions of linearly ordered features, as one typically encounters in problems such as whole genome…

Methodology · Statistics 2012-06-18 Seyoung Kim , Eric P. Xing

The development of next generation sequencing (NGS) technology and genotype imputation methods enabled researchers to measure both common and rare variants in genome-wide association studies (GWAS). Statistical methods have been proposed to…

Methodology · Statistics 2018-12-14 XIaoyu Cai , Lo-Bin Chang , Chi Song

Differential abundance (DA) analysis in microbiome studies has recently been used to uncover a plethora of associations between microbial composition and various health conditions. While current approaches to DA typically apply only to…

Methodology · Statistics 2026-01-19 Simon Fontaine , Nisha J. D'Silva , Marcell Costa de Medeiros , Grace Y. Chen , Ji Zhu , Gen Li

Sparse deep learning aims to address the challenge of huge storage consumption by deep neural networks, and to recover the sparse structure of target functions. Although tremendous empirical successes have been achieved, most sparse deep…

Machine Learning · Statistics 2020-11-17 Jincheng Bai , Qifan Song , Guang Cheng

Additive nonparametric regression models provide an attractive tool for variable selection in high dimensions when the relationship between the response and predictors is complex. They offer greater flexibility compared to parametric…

Machine Learning · Statistics 2016-07-12 Garret Vo , Debdeep Pati

Sparse Bayesian learning is a state-of-the-art supervised learning algorithm that can choose a subset of relevant samples from the input data and make reliable probabilistic predictions. However, in the presence of high-dimensional data…

Machine Learning · Computer Science 2020-01-10 Bingbing Jiang , Chang Li , Maarten de Rijke , Xin Yao , Huanhuan Chen

It is well known that in a supervised classification setting when the number of features is smaller than the number of observations, Fisher's linear discriminant rule is asymptotically Bayes. However, there are numerous modern applications…

Machine Learning · Statistics 2014-09-17 Irina Gaynanova , James G. Booth , Martin T. Wells

Quantile regression has become a valuable tool to analyze heterogeneous covaraite-response associations that are often encountered in practice. The development of quantile regression methodology for high-dimensional covariates primarily…

Methodology · Statistics 2015-07-06 Qi Zheng , Limin Peng , Xuming He

Sparse estimation methods are aimed at using or obtaining parsimonious representations of data or models. They were first dedicated to linear variable selection but numerous extensions have now emerged such as structured sparsity or kernel…

Machine Learning · Computer Science 2011-11-24 Francis Bach , Rodolphe Jenatton , Julien Mairal , Guillaume Obozinski

In probabilistic classification, a discriminative model based on the softmax function has a potential limitation in that it assumes unimodality for each class in the feature space. The mixture model can address this issue, although it leads…

Machine Learning · Computer Science 2021-05-10 Hideaki Hayashi , Seiichi Uchida

Clustering analysis is one of the most widely used statistical tools in many emerging areas such as microarray data analysis. For microarray and other high-dimensional data, the presence of many noise variables may mask underlying…

Machine Learning · Statistics 2008-03-26 Benhuai Xie , Wei Pan , Xiaotong Shen

A genome-wide association study (GWAS) correlates marker variation with trait variation in a sample of individuals. Each study subject is genotyped at a multitude of SNPs (single nucleotide polymorphisms) spanning the genome. Here we assume…

Machine Learning · Statistics 2019-01-14 Kevin L. Keys , Gary K. Chen , Kenneth Lange