English

Horseshoe Forests for High-Dimensional Causal Survival Analysis

Methodology 2026-05-08 v3 Machine Learning

Abstract

We develop a Bayesian tree ensemble model to estimate heterogeneous treatment effects in censored survival data with high-dimensional covariates. Instead of imposing sparsity through the tree structure, we place a horseshoe prior directly on the step heights to achieve adaptive global-local shrinkage. This strategy allows flexible regularisation and reduces noise. We develop a reversible jump Gibbs sampler to accommodate the non-conjugate horseshoe prior within the tree ensemble framework. We show through extensive simulations that the method accurately estimates treatment effects in high-dimensional covariate spaces, at various sparsity levels, and under non-linear treatment effect functions. We further illustrate the practical utility of the proposed approach by a re-analysis of pancreatic ductal adenocarcinoma (PDAC) survival data from The Cancer Genome Atlas.

Keywords

Cite

@article{arxiv.2507.22004,
  title  = {Horseshoe Forests for High-Dimensional Causal Survival Analysis},
  author = {Tijn Jacobs and Wessel N. van Wieringen and Stéphanie L. van der Pas},
  journal= {arXiv preprint arXiv:2507.22004},
  year   = {2026}
}
R2 v1 2026-07-01T04:24:26.778Z