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We propose a software platform that integrates methods and tools for multi-objective parameter auto- tuning in tissue image segmentation workflows. The goal of our work is to provide an approach for improving the accuracy of nucleus/cell…

Distributed, Parallel, and Cluster Computing · Computer Science 2018-10-09 Luis F. R. Taveira , Tahsin Kurc , Alba C. M. A. Melo , Jun Kong , Erich Bremer , Joel H. Saltz , George Teodoro

Every year millions of people die due to disease of Cancer. Due to its invasive nature it is very complex to cure even in primary stages. Hence, only method to survive this disease completely is via forecasting by analyzing the early…

Computer Vision and Pattern Recognition · Computer Science 2018-08-24 Shivam Singh , Stuti Pathak

We present an efficient deep learning approach for the challenging task of tumor segmentation in multisequence MR images. In recent years, Convolutional Neural Networks (CNN) have achieved state-of-the-art performances in a large variety of…

Computer Vision and Pattern Recognition · Computer Science 2018-07-24 Pawel Mlynarski , Hervé Delingette , Antonio Criminisi , Nicholas Ayache

Many functional and structural neuroimaging studies call for accurate morphometric segmentation of different brain structures starting from image intensity values of MRI scans. Current automatic (multi-) atlas-based segmentation strategies…

Image and Video Processing · Electrical Eng. & Systems 2019-09-27 Dennis Bontempi , Sergio Benini , Alberto Signoroni , Michele Svanera , Lars Muckli

Accurate segmentation of thalamic nuclei from magnetic resonance images is important due to the distinct roles of these nuclei in overall brain function and to their differential involvement in neurological and psychiatric disorders.…

Image and Video Processing · Electrical Eng. & Systems 2025-12-08 Anqi Feng , Zhangxing Bian , Samuel W. Remedios , Savannah P. Hays , Blake E. Dewey , Alexa Colinco , Jiachen Zhuo , Dan Benjamini , Jerry L. Prince

We propose a novel weakly supervised method to improve the boundary of the 3D segmented nuclei utilizing an over-segmented image. This is motivated by the observation that current state-of-the-art deep learning methods do not result in…

Computer Vision and Pattern Recognition · Computer Science 2021-08-31 S. Shailja , Jiaxiang Jiang , B. S. Manjunath

Precise 3D segmentation of infant brain tissues is an essential step towards comprehensive volumetric studies and quantitative analysis of early brain developement. However, computing such segmentations is very challenging, especially for…

Computer Vision and Pattern Recognition · Computer Science 2017-12-20 Jose Dolz , Christian Desrosiers , Li Wang , Jing Yuan , Dinggang Shen , Ismail Ben Ayed

Nuclei segmentation is both an important and in some ways ideal task for modern computer vision methods, e.g. convolutional neural networks. While recent developments in theory and open-source software have made these tools easier to…

Computer Vision and Pattern Recognition · Computer Science 2019-01-30 Aarno Oskar Vuola , Saad Ullah Akram , Juho Kannala

The quantitative analysis of cellular membranes helps understanding developmental processes at the cellular level. Particularly 3D microscopic image data offers valuable insights into cell dynamics, but error-free automatic segmentation…

Computer Vision and Pattern Recognition · Computer Science 2018-10-17 Dennis Eschweiler , Thiago V. Spina , Rohan C. Choudhury , Elliot Meyerowitz , Alexandre Cunha , Johannes Stegmaier

In comparative neuroanatomy, the characterization of brain cytoarchitecture is critical to a better understanding of brain structure and function, as it helps to distill information on the development, evolution, and distinctive features of…

Image and Video Processing · Electrical Eng. & Systems 2023-11-07 Valentina Vadori , Jean-Marie Graïc , Livio Finos , Livio Corain , Antonella Peruffo , Enrico Grisan

Deep convolutional neural networks (CNNs) have been intensively used for multi-class segmentation of data from different modalities and achieved state-of-the-art performances. However, a common problem when dealing with large, high…

Computer Vision and Pattern Recognition · Computer Science 2018-04-13 Chengjia Wang , Tom MacGillivray , Gillian Macnaught , Guang Yang , David Newby

3D microscopic cerebrovascular images are characterized by their high resolution, presenting significant annotation challenges, large data volumes, and intricate variations in detail. Together, these factors make achieving high-quality,…

Computer Vision and Pattern Recognition · Computer Science 2024-11-15 Xi Lin , Shixuan Zhao , Xinxu Wei , Amir Shmuel , Yongjie Li

Automatic tissue segmentation and nuclei detection is an important task in pathology, aiding in biomarker extraction and discovery. The panoptic segmentation of nuclei and tissue in advanced melanoma (PUMA) challenge aims to improve tissue…

Computer Vision and Pattern Recognition · Computer Science 2025-03-18 Negar Shahamiri , Moritz Rempe , Lukas Heine , Jens Kleesiek , Fabian Hörst

Maps of brain microarchitecture are important for understanding neurological function and behavior, including alterations caused by chronic conditions such as neurodegenerative disease. Techniques such as knife-edge scanning microscopy…

Image and Video Processing · Electrical Eng. & Systems 2020-02-06 Leila Saadatifard , Aryan Mobiny , Pavel Govyadinov , Hien Nguyen , David Mayerich

Large pre-trained models with their numerous model parameters and extensive training datasets have shown excellent performance in various tasks. Many publicly available medical image datasets do not have a sufficient amount of data so there…

Image and Video Processing · Electrical Eng. & Systems 2024-03-12 Jianhao Xie , Ziang Zhang , Guibo Luo , Yuesheng Zhu

3D imaging enables accurate diagnosis by providing spatial information about organ anatomy. However, using 3D images to train AI models is computationally challenging because they consist of 10x or 100x more pixels than their 2D…

Accurate segmentation of different sub-regions of gliomas including peritumoral edema, necrotic core, enhancing and non-enhancing tumor core from multimodal MRI scans has important clinical relevance in diagnosis, prognosis and treatment of…

Computer Vision and Pattern Recognition · Computer Science 2018-12-05 Xue Feng , Nicholas Tustison , Craig Meyer

In computational pathology, automatic nuclei instance segmentation plays an essential role in whole slide image analysis. While many computerized approaches have been proposed for this task, supervised deep learning (DL) methods have shown…

Image and Video Processing · Electrical Eng. & Systems 2023-08-04 Amirreza Mahbod , Christine Polak , Katharina Feldmann , Rumsha Khan , Katharina Gelles , Georg Dorffner , Ramona Woitek , Sepideh Hatamikia , Isabella Ellinger

Cerebral Microbleeds (CMBs) are chronic deposits of small blood products in the brain tissues, which have explicit relation to various cerebrovascular diseases depending on their anatomical location, including cognitive decline,…

Image and Video Processing · Electrical Eng. & Systems 2023-06-27 Jun-Ho Kim , Young Noh , Haejoon Lee , Seul Lee , Woo-Ram Kim , Koung Mi Kang , Eung Yeop Kim , Mohammed A. Al-masni , Dong-Hyun Kim