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COVID-19 has challenged health systems to learn how to learn. This paper describes the context, methods and challenges for learning to improve COVID-19 care at one academic health center. Challenges to learning include: (1) choosing a right…

The abrupt outbreak of the COVID-19 pandemic was the most significant event in 2020, which had profound and lasting impacts across the world. Studies on energy markets observed a decline in energy demand and changes in energy consumption…

Signal Processing · Electrical Eng. & Systems 2021-10-04 Ziyun Wang , Hao Wang

The spread of COVID-19 makes it essential to investigate its prevalence. In such investigation research, as far as we know, the widely-used sampling methods didn't use the information sufficiently about the numbers of the previously…

Applications · Statistics 2022-01-04 Ze Liu , Siyu Yi , Jianghu , Dong , Min-Qian Liu , Yongdao Zhou

In this paper, we consider the problem of designing optimal pooling matrix for group testing (for example, for COVID-19 virus testing) with the constraint that no more than $r>0$ samples can be pooled together, which we call "dilution…

Quantitative Methods · Quantitative Biology 2020-08-06 Jirong Yi , Myung Cho , Xiaodong Wu , Raghu Mudumbai , Weiyu Xu

The outbreak of the global COVID-19 pandemic results in unprecedented demand for fast and efficient testing of large numbers of patients for the presence of SARS-CoV-2 coronavirus. Beside technical improvements of the cost and speed of…

Methodology · Statistics 2020-12-16 Andrzej Jaszkiewicz

We propose a compressed sensing-based testing approach with a practical measurement design and a tuning-free and noise-robust algorithm for detecting infected persons. Compressed sensing results can be used to provably detect a small number…

Information Theory · Computer Science 2023-05-15 Hendrik Bernd Petersen , Bubacarr Bah , Peter Jung

The COVID-19 pandemic represents the most significant public health disaster since the 1918 influenza pandemic. During pandemics such as COVID-19, timely and reliable spatio-temporal forecasting of epidemic dynamics is crucial. Deep…

Machine Learning · Computer Science 2020-11-25 Lijing Wang , Aniruddha Adiga , Srinivasan Venkatramanan , Jiangzhuo Chen , Bryan Lewis , Madhav Marathe

Fast testing can help mitigate the coronavirus disease 2019 (COVID-19) pandemic. Despite their accuracy for single sample analysis, infectious diseases diagnostic tools, like RT-PCR, require substantial resources to test large populations.…

Quantitative Methods · Quantitative Biology 2020-04-08 Junan Zhu , Kristina Rivera , Dror Baron

This paper is based on the observation that, during Covid-19 epidemic, the choice of which individuals should be tested has an important impact on the effectiveness of selective confinement measures. This decision problem is closely related…

Physics and Society · Physics 2020-12-24 Matthias Pezzutto , Nicolas Bono Rossello , Luca Schenato , Emanuele Garone

The COVID-19 pandemic has impacted lives and economies across the globe, leading to many deaths. While vaccination is an important intervention, its roll-out is slow and unequal across the globe. Therefore, extensive testing still remains…

There are multiple testing methods to ascertain an infection in an individual and they vary in their performances, cost and delay. Unfortunately, better performing tests are sometimes costlier and time consuming and can only be done for a…

Social and Information Networks · Computer Science 2021-06-17 Harish Sasikumar , Manoj Varma

Numerous COVID-19 clinical decision support systems have been developed. However many of these systems do not have the merit for validity due to methodological shortcomings including algorithmic bias. Methods Logistic regression models were…

Machine Learning · Computer Science 2021-11-02 Yifan Li , Garrett Yoon , Mustafa Nasir-Moin , David Rosenberg , Sean Neifert , Douglas Kondziolka , Eric Karl Oermann

In pandemics or epidemics, public health authorities need to rapidly test a large number of individuals, both to determine the line of treatment as well as to know the spread of infection to plan containment, mitigation and future…

Other Quantitative Biology · Quantitative Biology 2020-03-31 Tarun Jain , Bijendra Nath Jain

The COVID-19 pandemic continues to affect the conduct of clinical trials globally. Complications may arise from pandemic-related operational challenges such as site closures, travel limitations and interruptions to the supply chain for the…

COVID-19 testing has become a standard approach for estimating prevalence which then assist in public health decision making to contain and mitigate the spread of the disease. The sampling designs used are often biased in that they do not…

Methodology · Statistics 2022-02-24 Daniel Andrés Díaz-Pachón , J Sunil Rao

We demonstrate an approach to replicate and forecast the spread of the SARS-CoV-2 (COVID-19) pandemic using the toolkit of probabilistic programming languages (PPLs). Our goal is to study the impact of various modeling assumptions and…

Machine Learning · Statistics 2022-03-08 Swapneel Mehta , Noah Kasmanoff

Testing is an important part of tackling the COVID-19 pandemic. Availability of testing is a bottleneck due to constrained resources and effective prioritization of individuals is necessary. Here, we discuss the impact of different…

Machine Learning · Computer Science 2020-07-30 Hagit Grushka-Cohen , Raphael Cohen , Bracha Shapira , Jacob Moran-Gilad , Lior Rokach

This paper extends the canonical model of epidemiology, SIRD model, to allow for time varying parameters for real-time measurement of the stance of the COVID-19 pandemic. Time variation in model parameters is captured using the generalized…

Populations and Evolution · Quantitative Biology 2021-02-11 Cem Cakmakli , Yasin Simsek

During the COVID-19 pandemic, case isolation emerged as a key non-pharmaceutical intervention in pandemic response. Its effectiveness hinges on the timing of isolation, which is often dictated by the onset of contagiousness. While…

Populations and Evolution · Quantitative Biology 2025-02-03 Jiahao Diao , Rebecca H. Chisholm , Nicholas Geard , James M. McCaw

The COVID-19 pandemic prompted a surge in computational models to simulate disease dynamics and guide interventions. Agent-based models (ABMs) are well-suited to capture population and environmental heterogeneity, but their rapid deployment…