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Multimodal registration is a challenging problem in medical imaging due the high variability of tissue appearance under different imaging modalities. The crucial component here is the choice of the right similarity measure. We make a step…

Computer Vision and Pattern Recognition · Computer Science 2016-09-20 Martin Simonovsky , Benjamín Gutiérrez-Becker , Diana Mateus , Nassir Navab , Nikos Komodakis

Registration of images with pathologies is challenging due to tissue appearance changes and missing correspondences caused by the pathologies. Moreover, mass effects as observed for brain tumors may displace tissue, creating larger…

Image and Video Processing · Electrical Eng. & Systems 2020-08-19 Xu Han , Zhengyang Shen , Zhenlin Xu , Spyridon Bakas , Hamed Akbari , Michel Bilello , Christos Davatzikos , Marc Niethammer

Deformable image registration (DIR) is an enabling technology in many diagnostic and therapeutic tasks. Despite this, DIR algorithms have limited clinical use, largely due to a lack of benchmark datasets for quality assurance during…

Computer Vision and Pattern Recognition · Computer Science 2025-01-17 Edward R Criscuolo , Yao Hao , Zhendong Zhang , Trevor McKeown , Deshan Yang

Purpose: Deformable Image Registration (DIR) can benefit from additional guidance using corresponding landmarks in the images. However, the benefits thereof are largely understudied, especially due to the lack of automatic landmark…

Computer Vision and Pattern Recognition · Computer Science 2023-02-28 Monika Grewal , Jan Wiersma , Henrike Westerveld , Peter A. N. Bosman , Tanja Alderliesten

We propose a registration algorithm for 2D CT/MRI medical images with a new unsupervised end-to-end strategy using convolutional neural networks. The contributions of our algorithm are threefold: (1) We transplant traditional image…

Computer Vision and Pattern Recognition · Computer Science 2018-01-23 Siyuan Shan , Wen Yan , Xiaoqing Guo , Eric I-Chao Chang , Yubo Fan , Yan Xu

Deformable image registration is a very important field of research in medical imaging. Recently multiple deep learning approaches were published in this area showing promising results. However, drawbacks of deep learning methods are the…

Computer Vision and Pattern Recognition · Computer Science 2020-02-11 Tobias Fechter , Dimos Baltas

Medical image registration is a critical component of clinical imaging workflows, enabling accurate longitudinal assessment, multi-modal data fusion, and image-guided interventions. Intensity-based approaches often struggle with…

Computer Vision and Pattern Recognition · Computer Science 2026-03-17 Eytan Kats , Mattias P. Heinrich

Microscopy images obtained from multiple camera lenses or sensors in biological experiments provide a comprehensive understanding of objects from diverse perspectives. However, using multiple microscope setups increases the risk of…

Image and Video Processing · Electrical Eng. & Systems 2024-07-18 Ruixiong Wang , Stephen Cross , Alin Achim

Deformable Image Registration (DIR) plays a significant role in quantifying deformation in medical data. Recent Deep Learning methods have shown promising accuracy and speedup for registering a pair of medical images. However, in 4D (3D +…

Image and Video Processing · Electrical Eng. & Systems 2023-05-26 Xiao Liang , Shan Lin , Fei Liu , Dimitri Schreiber , Michael Yip

Deformable image registration poses a challenging problem where, unlike most deep learning tasks, a complex relationship between multiple coordinate systems has to be considered. Although data-driven methods have shown promising…

Computer Vision and Pattern Recognition · Computer Science 2025-03-11 Vasiliki Sideri-Lampretsa , Nil Stolt-Ansó , Huaqi Qiu , Julian McGinnis , Wenke Karbole , Martin Menten , Daniel Rueckert

Background: Voxel-based analysis (VBA) for population level radiotherapy (RT) outcomes modeling requires topology preserving inter-patient deformable image registration (DIR) that preserves tumors on moving images while avoiding unrealistic…

Image and Video Processing · Electrical Eng. & Systems 2024-11-28 Jue Jiang , Chloe Min Seo Choi , Maria Thor , Joseph O. Deasy , Harini Veeraraghavan

Image registration is essential for medical image applications where alignment of voxels across multiple images is needed for qualitative or quantitative analysis. With recent advancements in deep neural networks and parallel computing,…

Image and Video Processing · Electrical Eng. & Systems 2025-07-23 Yi Zhang , Yidong Zhao , Hui Xue , Peter Kellman , Stefan Klein , Qian Tao

In adaptive radiotherapy, deformable image registration is often conducted between the planning CT and treatment CT (or cone beam CT) to generate a deformation vector field (DVF) for dose accumulation and contour propagation. The auto…

Medical Physics · Physics 2015-06-12 Xuejun Gu , Bin Dong , Jing Wang , John Yordy , Loren Mell , Xun Jia , Steve B. Jiang

Deformable image registration plays an essential role in various medical image tasks. Existing deep learning-based deformable registration frameworks primarily utilize convolutional neural networks (CNNs) or Transformers to learn features…

Computer Vision and Pattern Recognition · Computer Science 2024-11-26 Jiong Wu , Kuang Gong

We propose a novel non-rigid image registration algorithm that is built upon fully convolutional networks (FCNs) to optimize and learn spatial transformations between pairs of images to be registered. Different from most existing deep…

Computer Vision and Pattern Recognition · Computer Science 2017-09-05 Hongming Li , Yong Fan

Image registration is a fundamental task for medical imaging. Resampling of the intensity values is required during registration and better spatial resolution with finer and sharper structures can improve the resampling performance and…

Image and Video Processing · Electrical Eng. & Systems 2022-01-03 Kaicong Sun , Sven Simon

We present a method to predict image deformations based on patch-wise image appearance. Specifically, we design a patch-based deep encoder-decoder network which learns the pixel/voxel-wise mapping between image appearance and registration…

Computer Vision and Pattern Recognition · Computer Science 2016-07-11 Xiao Yang , Roland Kwitt , Marc Niethammer

Image registration has traditionally been done using two distinct approaches: learning based methods, relying on robust deep neural networks, and optimization-based methods, applying complex mathematical transformations to warp images…

Computer Vision and Pattern Recognition · Computer Science 2024-01-22 Gabriel De Araujo , Shanlin Sun , Xiaohui Xie

Deformable Image Registration (DIR) is essential for aligning medical images that exhibit anatomical variations, facilitating applications such as disease tracking and radiotherapy planning. While classical iterative methods and deep…

Computer Vision and Pattern Recognition · Computer Science 2025-09-08 Jihe Li , Xiang Liu , Fabian Zhang , Xia Li , Xixin Cao , Ye Zhang , Joachim Buhmann

We study the problem of registration for medical CT images from a novel perspective -- the sensitivity to degree of deformations in CT images. Although some learning-based methods have shown success in terms of average accuracy, their…

Computer Vision and Pattern Recognition · Computer Science 2023-05-25 Xinyu Zhao , Sa Huang , Wei Pang , You Zhou