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Deep learning (DL) image registration methods amortize the costly pair-wise iterative optimization by training deep neural networks to predict the optimal transformation in one fast forward-pass. In this work, we bridge the gap between…

Image and Video Processing · Electrical Eng. & Systems 2022-09-13 Huaqi Qiu , Kerstin Hammernik , Chen Qin , Chen Chen , Daniel Rueckert

Deep Learning in Image Registration (DLIR) methods have been tremendously successful in image registration due to their speed and ability to incorporate weak label supervision at training time. However, existing DLIR methods forego many of…

Computer Vision and Pattern Recognition · Computer Science 2025-05-06 Rohit Jena , Pratik Chaudhari , James C. Gee

While deep learning has achieved significant advances in accuracy for medical image segmentation, its benefits for deformable image registration have so far remained limited to reduced computation times. Previous work has either focused on…

Computer Vision and Pattern Recognition · Computer Science 2018-12-06 Alessa Hering , Sven Kuckertz , Stefan Heldmann , Mattias Heinrich

Parametric spatial transformation models have been successfully applied to image registration tasks. In such models, the transformation of interest is parameterized by a fixed set of basis functions as for example B-splines. Each basis…

Computer Vision and Pattern Recognition · Computer Science 2019-06-25 Robin Sandkühler , Simon Andermatt , Grzegorz Bauman , Sylvia Nyilas , Christoph Jud , Philippe C. Cattin

Recent works in medical image registration have proposed the use of Implicit Neural Representations, demonstrating performance that rivals state-of-the-art learning-based methods. However, these implicit representations need to be optimized…

Image and Video Processing · Electrical Eng. & Systems 2023-10-04 Louis D. van Harten , Jaap Stoker , Ivana Išgum

Pathologists need to combine information from differently stained pathology slices for accurate diagnosis. Deformable image registration is a necessary technique for fusing multi-modal pathology slices. This paper proposes a hybrid deep…

Image and Video Processing · Electrical Eng. & Systems 2024-10-28 Chulong Zhang , Yuming Jiang , Na Li , Zhicheng Zhang , Md Tauhidul Islam , Jingjing Dai , Lin Liu , Wenfeng He , Wenjian Qin , Jing Xiong , Yaoqin Xie , Xiaokun Liang

Cortical surface registration is a fundamental tool for neuroimaging analysis that has been shown to improve the alignment of functional regions relative to volumetric approaches. Classically, image registration is performed by optimizing a…

Computer Vision and Pattern Recognition · Computer Science 2022-03-25 Mohamed A. Suliman , Logan Z. J. Williams , Abdulah Fawaz , Emma C. Robinson

Image-guided interventions are saving the lives of a large number of patients where the image registration problem should indeed be considered as the most complex and complicated issue to be tackled. On the other hand, the recently huge…

Image and Video Processing · Electrical Eng. & Systems 2020-08-14 Hamid Reza Boveiri , Raouf Khayami , Reza Javidan , Ali Reza MehdiZadeh

Deformable image registration, i.e., the task of aligning multiple images into one coordinate system by non-linear transformation, serves as an essential preprocessing step for neuroimaging data. Recent research on deformable image…

Computer Vision and Pattern Recognition · Computer Science 2022-12-08 Yao Su , Xin Dai , Lifang He , Xiangnan Kong

Deep learning has revolutionized medical image registration by achieving unprecedented speeds, yet its clinical application is hindered by a limited ability to generalize beyond the training domain, a critical weakness given the typically…

Computer Vision and Pattern Recognition · Computer Science 2026-02-02 Fengting Zhang , Yue He , Qinghao Liu , Yaonan Wang , Xiang Chen , Hang Zhang

Multimodal image registration (MIR) is a fundamental procedure in many image-guided therapies. Recently, unsupervised learning-based methods have demonstrated promising performance over accuracy and efficiency in deformable image…

Computer Vision and Pattern Recognition · Computer Science 2020-11-13 Zhe Xu , Jiangpeng Yan , Jie Luo , Xiu Li , Jayender Jagadeesan

Image registration plays an important role in comparing images. It is particularly important in analyzing medical images like CT, MRI, PET, etc. to quantify different biological samples, to monitor disease progression and to fuse different…

Computer Vision and Pattern Recognition · Computer Science 2018-10-22 Abdullah Nazib , Clinton Fookes , Dimitri Perrin

Image registration with deep neural networks has become an active field of research and exciting avenue for a long standing problem in medical imaging. The goal is to learn a complex function that maps the appearance of input image pairs to…

Computer Vision and Pattern Recognition · Computer Science 2019-07-23 Matthew C. H. Lee , Ozan Oktay , Andreas Schuh , Michiel Schaap , Ben Glocker

Deformable image registration estimates voxel-wise correspondences between images through spatial transformations, and plays a key role in medical imaging. While deep learning methods have significantly reduced runtime, efficiently handling…

Computer Vision and Pattern Recognition · Computer Science 2025-10-28 Tianran Li , Marius Staring , Yuchuan Qiao

Evaluating deformable image registration (DIR) is challenging due to the inherent trade-off between achieving high alignment accuracy and maintaining deformation regularity. However, most existing DIR works either address this trade-off…

Computer Vision and Pattern Recognition · Computer Science 2025-10-14 Vasiliki Sideri-Lampretsa , Daniel Rueckert , Huaqi Qiu

This paper presents a novel approach, termed {\em Temporal Latent Residual Network (TLRN)}, to predict a sequence of deformation fields in time-series image registration. The challenge of registering time-series images often lies in the…

Computer Vision and Pattern Recognition · Computer Science 2026-01-13 Nian Wu , Jiarui Xing , Miaomiao Zhang

Deformable image registration between Computed Tomography (CT) images and Magnetic Resonance (MR) imaging is essential for many image-guided therapies. In this paper, we propose a novel translation-based unsupervised deformable image…

Image and Video Processing · Electrical Eng. & Systems 2020-09-22 Zhe Xu , Jie Luo , Jiangpeng Yan , Ritvik Pulya , Xiu Li , William Wells , Jayender Jagadeesan

Deformable image registration, estimating the spatial transformation between different images, is an important task in medical imaging. Many previous studies have used learning-based methods for multi-stage registration to perform 3D image…

Computer Vision and Pattern Recognition · Computer Science 2024-07-23 Jian-Qing Zheng , Ziyang Wang , Baoru Huang , Ngee Han Lim , Tonia Vincent , Bartlomiej W. Papiez

Image registration is a crucial task in signal processing, but it often encounters issues with stability and efficiency. Non-learning registration approaches rely on optimizing similarity metrics between fixed and moving images, which can…

Computer Vision and Pattern Recognition · Computer Science 2023-03-28 Zihao Wang , Hervé Delingette

Objective: Deep learning-based deformable image registration has achieved strong accuracy, but remains sensitive to variations in input image characteristics such as artifacts, field-of-view mismatch, or modality difference. We aim to…

Computer Vision and Pattern Recognition · Computer Science 2025-09-15 Yihao Liu , Junyu Chen , Lianrui Zuo , Shuwen Wei , Brian D. Boyd , Carmen Andreescu , Olusola Ajilore , Warren D. Taylor , Aaron Carass , Bennett A. Landman
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