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Astronomical observations suggest that the Universe may be anisotropic on the largest scales. In order to model this situation, we develop a new approach to cosmology that allows for large-scale anisotropy to emerge from the growth of…

General Relativity and Quantum Cosmology · Physics 2023-06-26 Theodore Anton , Timothy Clifton

The spongy mesophyll is a complex, porous tissue found in plant leaves that enables carbon capture and provides mechanical stability. Unlike many other biological tissues, which remain confluent throughout development, the spongy mesophyll…

A one-dimensional cellular automaton with a probabilistic evolution rule can generate stochastic surface growth in $(1 + 1)$ dimensions. Two such discrete models of surface growth are constructed from a probabilistic cellular automaton…

Statistical Mechanics · Physics 2015-06-25 Pratip Bhattacharyya

Convergent extension of epithelial tissue is a key motif of animal morphogenesis. On a coarse scale, cell motion resembles laminar fluid flow; yet in contrast to a fluid, epithelial cells adhere to each other and maintain the tissue layer…

Biological Physics · Physics 2024-10-04 Nikolas H. Claussen , Fridtjof Brauns , Boris I. Shraiman

When they are damaged or injured, soft biological tissues are able to self-repair and heal. Mechanics is critical during the healing process, as the damaged extracellular matrix (ECM) tends to be replaced with a new undamaged ECM supporting…

Computational Engineering, Finance, and Science · Computer Science 2021-12-08 Di Zuo , Yiqian He , Stéphane Avril , Haitian Yang , Klaus Hackl

We derive an asymptotically consistent morphoelastic shell model to describe the finite deformations of biological tissues using the variational asymptotical method. Biological materials may exhibit remarkable compressibility when under…

Soft Condensed Matter · Physics 2024-07-23 Xiang Yu , Xiaoyi Chen

The buckling of a soft elastic sample under growth or swelling has highlighted a new interest in materials science, morphogenesis, and biology or physiology. Indeed, the change of mass or volume is a common fact of any living species, and…

Soft Condensed Matter · Physics 2023-09-21 Martine Ben Amar

We formulate a relaxed linear elastic micromorphic continuum model with symmetric Cauchy force-stresses and curvature contribution depending only on the micro-dislocation tensor. Our relaxed model is still able to fully describe rotation of…

Mathematical Physics · Physics 2015-06-16 Patrizio Neff , Ionel-Dumitrel Ghiba , Angela Madeo , Luca Placidi , Giuseppe Rosi

The mechanism by which cells measure the dimension of the organ in which they are embedded, and slow down their growth when the final size is reached, is a long-standing problem of developmental biology. The role of mechanics in this…

Biological Physics · Physics 2023-07-19 Alexander Erlich , Pierre Recho

We study a shape evolution framework in which the deformation of shapes from time t to t + dt is governed by a regularized anisotropic elasticity model. More precisely, we assume that at each time shapes are infinitesimally deformed from a…

Optimization and Control · Mathematics 2019-01-01 Dai-Ni Hsieh , Sylvain Arguillère , Nicolas Charon , Michael I. Miller , Laurent Younes

Accurate predictions and representations of plant growth patterns in simulated and controlled environments are important for addressing various challenges in plant phenomics research. This review explores various works on state-of-the-art…

Quantitative Methods · Quantitative Biology 2025-07-17 Mohamed Debbagh , Shangpeng Sun , Mark Lefsrud

Order and alignment are ubiquitous in growing colonies of rod-shaped bacteria due to the nematic properties of the constituent particles. These effects are the result of the active stresses generated by growth, passive mechanical…

Soft Condensed Matter · Physics 2022-07-07 Jonas Isensee , Lukas Hupe , Ramin Golestanian , Philip Bittihn

We apply a recently developed model of cytoskeletal force generation to study a cell intrinsic contractility, as well as its response to external loading. The model is based on a non-equilibrium thermodynamic treatment of the…

Subcellular Processes · Quantitative Biology 2015-06-19 Mirko Maraldi , Clara Valero , Krishna Garikipati

There is significant interest in modelling the mechanics and physics of growth of soft biological systems such as tumors and bacterial biofilms. Solid tumors account for more than 85% of cancer mortality and bacterial biofilms account for a…

Soft Condensed Matter · Physics 2024-03-29 Chockalingam Senthilnathan , Tal Cohen

The mechanical behaviour of solid biological tissues has long been described using models based on classical continuum mechanics. However, the classical continuum theories of elasticity and viscoelasticity cannot easily capture the…

Biological Physics · Physics 2017-05-16 Shakti N. Menon , Cameron L. Hall , Scott W. McCue , D. L. Sean McElwain

Existence and uniqueness of solutions for a class of models for stress-modulated growth is proven in one spatial dimension. The model features the multiplicative decomposition of the deformation gradient $F$ into an elastic part $F_e$ and a…

Analysis of PDEs · Mathematics 2022-11-28 Kira Bangert , Georg Dolzmann

Initial residual stress is omnipresent in biological tissues and soft matter, and can affect growth-induced pattern selection significantly. Here we demonstrate this effect experimentally by letting soft tubes grow in the presence or…

Soft Condensed Matter · Physics 2020-09-11 Yangkun Du , Chaofeng Lü , Congshan Liu , Zilong Han , Jian Li , Weiqi Chen , Shaoxing Qua , Michel Destrade

We consider a free boundary problem for a system of PDEs, modeling the growth of a biological tissue. A morphogen, controlling volume growth, is produced by specific cells and then diffused and absorbed throughout the domain. The geometric…

Analysis of PDEs · Mathematics 2017-11-22 Alberto Bressan , Marta Lewicka

We give a description of cell diffusion in a soft tissue, paying special attention to the coupling of force, matter, and microforce balance laws through a suitable dissipation principle. To this end, we cast our framework into a multi-level…

Soft Condensed Matter · Physics 2024-12-19 Amabile Tatone , Filippo Recrosi , Giuseppe Tomassetti

The stress fields of dislocations predicted by classical elasticity are known to be unrealistically large approaching the dislocation core, due to the singular nature of the theory. While in many cases this is remedied with the…

Materials Science · Physics 2015-05-22 Dariush Seif , Giacomo Po , Matous Mrovec , Markus Lazar , Christian Elsaesser , Peter Gumbsch
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