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We investigate disease spreading on eight empirical data sets of human contacts (mostly proximity networks recording who is close to whom, at what time). We compare three levels of representations of these data sets: temporal networks,…

Populations and Evolution · Quantitative Biology 2016-09-14 Petter Holme

The emergence or adaptation of pathogens may lead to epidemics, highlighting the need for a thorough understanding of pathogen evolution. The tradeoff hypothesis suggests that virulence evolves to reach an optimal transmission intensity…

Populations and Evolution · Quantitative Biology 2024-12-09 Daniel A. M. Villela

This paper studies a distributed continuous-time bi-virus model in which two competing viruses spread over a network consisting of multiple groups of individuals. Limiting behaviors of the network are characterized by analyzing the…

Optimization and Control · Mathematics 2019-01-04 Ji Liu , Philip E. Pare , Angelia Nedich , Choon Yik Tang , Carolyn L. Beck , Tamer Basar

We analyze the dynamics of a population of independent random walkers on a graph and develop a simple model of epidemic spreading. We assume that each walker visits independently the nodes of a finite ergodic graph in a discrete-time…

Physics and Society · Physics 2021-01-19 Michael Bestehorn , Alejandro P. Riascos , Thomas M. Michelitsch , Bernard A. Collet

Background: Recently developed techniques to study the spread of infectious diseases through networks make assumptions that the initial proportion infected is infinitesimal and the population behavior is static throughout the epidemic. The…

Populations and Evolution · Quantitative Biology 2012-08-17 Joel C. Miller

We study the global stability of a multistrain SIS model with superinfection and patch structure. We establish an iterative procedure to obtain a sequence of threshold parameters. By a repeated application of a result by Takeuchi et al.…

Dynamical Systems · Mathematics 2018-05-18 Attila Dénes , Yoshiaki Muroya , Gergely Röst

Mathematical models of infectious disease transmission typically neglect within-host dynamics. Yet within-host dynamics - including pathogen replication, host immune responses, and interactions with microbiota - are crucial not only for…

Populations and Evolution · Quantitative Biology 2023-12-20 Cameron A. Smith , Ben Ashby

Understanding dynamics of an infectious disease helps in designing appropriate strategies for containing its spread in a population. Recent mathematical models are aimed at studying dynamics of some specific types of infectious diseases. In…

Dynamical Systems · Mathematics 2015-02-05 P. Raja Sekhara Rao , M. Naresh Kumar

The use of network theory to model disease propagation on populations introduces important elements of reality to the classical epidemiological models. The use of random geometric graphs (RGG) is one of such network models that allows for…

Physics and Society · Physics 2016-12-21 Ernesto Estrada , Sandro Meloni , Matthew Sheerin , Yamir Moreno

The systematic study of large-scale networks has unveiled the ubiquitous presence of connectivity patterns characterized by large scale heterogeneities and unbounded statistical fluctuations. These features affect dramatically the behavior…

Other Quantitative Biology · Quantitative Biology 2007-05-23 Vittoria Colizza , Alain Barrat , Marc Barthelemy , Alessandro Vespignani

We propose a compartmental model for epidemiology wherein the population is split into groups with either comply or refuse to comply with protocols designed to slow the spread of a disease. Parallel to the disease spread, we assume that…

Dynamical Systems · Mathematics 2025-11-27 Christian Parkinson , Weinan Wang

Drug resistance and strong contacts actually play crucial roles in epidemic spread in complex systems. Nevertheless, neither theoretical model or methodology is proposed to address this. We thus consider an edge-based epidemic spread model…

Physics and Society · Physics 2017-09-13 Peng-Bi Cui , Lei Gao , Wei Wang

This article is concerned with a version of the contact process with sexual reproduction on a graph with two levels of interactions modeling metapopulations. The population is spatially distributed into patches and offspring are produced in…

Probability · Mathematics 2015-04-08 Eric Foxall , Nicolas Lanchier

The rapid worldwide spread of the severe acute respiratory syndrome (SARS) demonstrated the potential threat an infectious disease poses in a closely interconnected and interdependent world. Here we introduce a probabilistic model which…

Disordered Systems and Neural Networks · Physics 2009-11-10 L. Hufnagel , D. Brockmann , T. Geisel

We investigate the spatial dynamics of two disease epidemics reaching a three-species cyclic model. Regardless of their species, all individuals are susceptible to being infected with two different pathogens, which spread through…

Populations and Evolution · Quantitative Biology 2024-06-05 J. Menezes , E. Rangel

Viruses like influenza have long coevolved with host immune systems, gradually shaping the evolutionary trajectory of these pathogens. Host immune systems develop immunity against circulating strains, which in turn avoid extinction by…

Multiple viruses are widely studied because of their negative effect on the health of host as well as on whole population. The dynamics of coinfection is important in this case. We formulated a SIR model that describes the coinfection of…

Dynamical Systems · Mathematics 2019-05-14 Samia Ghersheen , Vladimir Kozlov , Vladimir G. Tkachev , Uno Wennergren

Coinfection phenomena are common in nature, yet there is a lack of analytical approaches for coinfection systems with a high number of circulating and interacting strains. In this paper, we investigated a coinfection SIS framework applied…

Populations and Evolution · Quantitative Biology 2026-02-06 Sten Madec , Nicola Cinardi , Erida Gjini

We review and introduce a generalized reaction-diffusion approach to epidemic spreading in a metapopulation modeled as a complex network. The metapopulation consists of susceptible and infected individuals that are grouped in subpopulations…

Physics and Society · Physics 2015-06-12 Halvor Lund , Ludvig Lizana , Ingve Simonsen

Source-sink systems are metapopulations of patches that can be of variable habitat quality. They can be seen as graphs, where vertices represent the patches, and the weighted oriented edges give the probability of dispersal from one patch…

Probability · Mathematics 2011-11-11 Vincent Bansaye , Amaury Lambert