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Single-photon emission computed tomography for myocardial perfusion imaging (MPI SPECT) is a widely used diagnostic tool for coronary artery disease. However, the procedure requires considerable scanning time, leading to patient discomfort…

Image and Video Processing · Electrical Eng. & Systems 2026-04-27 Zezhang Yang , Zitong Yu , Nuri Choi , Janice Tania , Wenxuan Xue , Barry A. Siegel , Abhinav K. Jha

Myocardial perfusion imaging using SPECT is widely utilized to diagnose coronary artery diseases, but image quality can be negatively affected in low-dose and few-view acquisition settings. Although various deep learning methods have been…

Quantitative measures of dopamine transporter (DaT) uptake in caudate, putamen, and globus pallidus derived from DaT-single-photon emission computed tomography (SPECT) images are being investigated as biomarkers to diagnose, assess disease…

Laser absorption spectroscopy (LAS) quantification is a popular tool used in measuring temperature and concentration of gases. It has low error tolerance, whereas current ML-based solutions cannot guarantee their measure reliability. In…

Neural and Evolutionary Computing · Computer Science 2024-08-21 Ruiyuan Kang , Panos Liatsis , Meixia Geng , Qingjie Yang

Ultra low radiation dose in X-ray Computed Tomography (CT) is an important clinical objective in order to minimize the risk of carcinogenesis. Compressed Sensing (CS) enables significant reductions in radiation dose to be achieved by…

Quantitative estimation of contrast agent concentration is made possible by spectral CT and material decomposition. There are several approaches to modulate the sensitivity of the imaging system to obtain the different spectral channels…

Medical Physics · Physics 2020-10-16 Matthew Tivnan , Wenying Wang , Grace Gang , Eleni Liapi , Peter Noel , J. Webster Stayman

Ultrasound computed tomography (USCT) is an emerging modality for breast imaging. Image reconstruction methods that incorporate accurate wave physics produce high resolution quantitative images of acoustic properties but are computationally…

Image and Video Processing · Electrical Eng. & Systems 2025-02-14 Luke Lozenski , Hanchen Wang , Fu Li , Mark A. Anastasio , Brendt Wohlberg , Youzuo Lin , Umberto Villa

Myocardial perfusion imaging (MPI) by single-photon emission computed tomography (SPECT) is widely applied for the diagnosis of cardiovascular diseases. Reducing the dose of the injected tracer is essential for lowering the patient's…

Computer Vision and Pattern Recognition · Computer Science 2023-05-18 Xiongchao Chen , Bo Zhou , Huidong Xie , Xueqi Guo , Qiong Liu , Albert J. Sinusas , Chi Liu

We developed a positron emission tomography (PET) system for multiple-isotope imaging. Our PET system, named multiple-isotope PET (MI-PET), can distinguish between different tracer nuclides using coincidence measurement of prompt…

X-ray energy spectrum plays an essential role in imaging and related tasks. Due to the high photon flux of clinical CT scanners, most of the spectrum estimation methods are indirect and are usually suffered from various limitations. The…

Medical Physics · Physics 2016-04-19 Wei Zhao , Qiude Zhang , Tianye Niu

The Lightfield Single Photon Emission Computed Tomography (L-SPECT) system is developed to overcome some of the drawbacks in conventional SPECT by applying the idea of plenoptic imaging. This system displayed improved performance in terms…

Image and Video Processing · Electrical Eng. & Systems 2020-08-19 Manu Francis , Murat Tahtali , Mark R Pickering

When a measurement falls outside the quantization or measurable range, it becomes saturated and cannot be used in classical reconstruction methods. For example, in C-arm angiography systems, which provide projection radiography,…

Computer Vision and Pattern Recognition · Computer Science 2017-01-04 Xiaolin Huang , Yan Xia , Lei Shi , Yixing Huang , Ming Yan , Joachim Hornegger , Andreas Maier

The compressed sensing (CS) framework leverages the sparsity of MR images to reconstruct from undersampled acquisitions. CS reconstructions involve one or more regularization parameters that weigh sparsity in transform domains against…

Myocardial perfusion imaging (MPI) with single-photon emission computed tomography (SPECT) is a widely used and cost-effective diagnostic tool for coronary artery disease. However, the lengthy scanning time in this imaging procedure can…

Computer Vision and Pattern Recognition · Computer Science 2025-04-24 Zezhang Yang , Zitong Yu , Nuri Choi , Abhinav K. Jha

Particle therapy is an established method to treat deep-seated tumours using accelerator-produced ion beams. For treatment planning, the precise knowledge of the relative stopping power (RSP) within the patient is vital. Conversion errors…

Single photon emission computed tomography (SPECT) is a well established clinical tool for functional imaging. A limitation of current SPECT systems is the use of mechanical collimation, where only a small fraction of the emitted photons is…

Numerical Analysis · Mathematics 2016-07-05 Sunghwan Moon , Markus Haltmeier

Clinical SPECT-MPI images of 345 patients acquired from a dedicated cardiac SPECT in list-mode format were retrospectively employed to predict normal-dose images from low-dose data at the half, quarter, and one-eighth-dose levels. A…

Modeling of the collimator-detector response (CDR) in SPECT reconstruction enables improved resolution and accuracy, and is thus important for quantitative imaging applications such as dosimetry. The implementation of CDR modeling, however,…

In this paper, we present a novel method for tomographic image reconstruction in SPECT imaging with a low number of projections. Deep convolutional neural networks (CNN) are employed in the new reconstruction method. Projection data from…

Artificial Intelligence · Computer Science 2021-08-10 Charalambos Chrysostomou , Loizos Koutsantonis , Christos Lemesios , Costas N. Papanicolas

The objective of quantitative photoacoustic tomography (QPAT) is to reconstruct optical and thermodynamic properties of heterogeneous media from data of absorbed energy distribution inside the media. There have been extensive theoretical…

Medical Physics · Physics 2019-10-08 Alexander V. Mamonov , Kui Ren