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Virtual Screening is an essential technique in the early phases of drug discovery, aimed at identifying promising drug candidates from vast molecular libraries. Recently, ligand-based virtual screening has garnered significant attention due…

Biomolecules · Quantitative Biology 2024-11-22 Gengmo Zhou , Zhen Wang , Feng Yu , Guolin Ke , Zhewei Wei , Zhifeng Gao

The amount of scientific papers published every day is daunting and constantly increasing. Keeping up with literature represents a challenge. If one wants to start exploring new topics it is hard to have a big picture without reading lots…

Information Retrieval · Computer Science 2020-11-10 Alberto Calderone

This paper presents TL;DR Progress, a new tool for exploring the literature on neural text summarization. It organizes 514~papers based on a comprehensive annotation scheme for text summarization approaches and enables fine-grained, faceted…

Computation and Language · Computer Science 2024-02-13 Shahbaz Syed , Khalid Al-Khatib , Martin Potthast

Recent advances in natural language processing (NLP) can be largely attributed to the advent of pre-trained language models such as BERT and RoBERTa. While these models demonstrate remarkable performance on general datasets, they can…

This is the second year of the TREC Deep Learning Track, with the goal of studying ad hoc ranking in the large training data regime. We again have a document retrieval task and a passage retrieval task, each with hundreds of thousands of…

Information Retrieval · Computer Science 2021-02-16 Nick Craswell , Bhaskar Mitra , Emine Yilmaz , Daniel Campos

The rapidly increasing number of scientific documents available publicly on the Internet creates the challenge of efficiently organizing and indexing these documents. Due to the time consuming and tedious nature of manual classification and…

Digital Libraries · Computer Science 2016-03-22 Lisa Posch

This report describes the participation of two Danish universities, University of Copenhagen and Aalborg University, in the international search engine competition on COVID-19 (the 2020 TREC-COVID Challenge) organised by the U.S. National…

The COVID-19 has brought about a significant challenge to the whole of humanity, but with a special burden upon the medical community. Clinicians must keep updated continuously about symptoms, diagnoses, and effectiveness of emergent…

Computation and Language · Computer Science 2020-12-02 Andres Carvallo , Denis Parra , Gabriel Rada , Daniel Perez , Juan Ignacio Vasquez , Camilo Vergara

Accurate and reliable search on online healthcare platforms is critical for user safety and service efficacy. Traditional methods, however, often fail to comprehend complex and nuanced user queries, limiting their effectiveness. Large…

Computation and Language · Computer Science 2025-12-04 Chuyue Wang , Jie Feng , Yuxi Wu , Hang Zhang , Zhiguo Fan , Bing Cheng , Wei Lin

Multi-modal image registration plays a critical role in precision medicine but faces challenges from non-linear intensity relationships and local optima. While deep learning models enable rapid inference, they often suffer from…

Image and Video Processing · Electrical Eng. & Systems 2026-04-14 Boya Wang , Ruizhe Li , Chao Chen , Xin Chen

In recent years a vast amount of visual content has been generated and shared from many fields, such as social media platforms, medical imaging, and robotics. This abundance of content creation and sharing has introduced new challenges,…

Computer Vision and Pattern Recognition · Computer Science 2022-11-01 Wei Chen , Yu Liu , Weiping Wang , Erwin Bakker , Theodoros Georgiou , Paul Fieguth , Li Liu , Michael S. Lew

Biomedical researchers face increasing challenges in navigating millions of publications in diverse domains. Traditional search engines typically return articles as ranked text lists, offering little support for global exploration or…

Information Retrieval · Computer Science 2026-01-29 Huan He , Xueqing Peng , Yutong Xie , Qijia Liu , Chia-Hsuan Chang , Lingfei Qian , Brian Ondov , Qiaozhu Mei , Hua Xu

The growing volume of biomedical scholarly document abstracts presents an increasing challenge in efficiently retrieving accurate and relevant information. To address this, we introduce a novel approach that integrates an optimized topic…

Computation and Language · Computer Science 2024-11-04 Parvez Zamil , Gollam Rabby , Md. Sadekur Rahman , Sören Auer

Academic literature reviews have traditionally relied on techniques such as keyword searches and accumulation of relevant back-references, using databases like Google Scholar or IEEEXplore. However, both the precision and accuracy of these…

Human-Computer Interaction · Computer Science 2024-08-27 Hongye An , Arpit Narechania , Emily Wall , Kai Xu

Biomedical queries often rely on a deep understanding of specialized knowledge such as gene regulatory mechanisms and pathological processes of diseases. They require detailed analysis of complex physiological processes and effective…

Computation and Language · Computer Science 2026-02-02 Congying Liu , Xingyuan Wei , Peipei Liu , Yiqing Shen , Yanxu Mao , Tiehan Cui

Document screening is a central task within Evidenced Based Medicine, which is a clinical discipline that supplements scientific proof to back medical decisions. Given the recent advances in DL (Deep Learning) methods applied to Information…

Information Retrieval · Computer Science 2021-04-20 Alexandros Ioannidis

Literature analysis is a key step in obtaining background information in biomedical research. However, it is difficult for researchers to obtain knowledge of their interests in an efficient manner because of the massive amount of the…

Information Retrieval · Computer Science 2016-11-03 Junseok Park , Gwangmin Kim , Dongjin Jang , Sungji Choo , Sunghwa Bae , Doheon Lee

Clinical trials are essential for drug development but are extremely expensive and time-consuming to conduct. It is beneficial to study similar historical trials when designing a clinical trial. However, lengthy trial documents and lack of…

Computation and Language · Computer Science 2022-10-11 Zifeng Wang , Jimeng Sun

Hard negatives are essential for training effective retrieval models. Hard-negative mining typically relies on ranking documents using cross-encoders or static embedding models based on similarity metrics such as cosine distance. Hard…

Information Retrieval · Computer Science 2025-12-23 Aarush Sinha , Pavan Kumar S , Roshan Balaji , Nirav Pravinbhai Bhatt

We seek to address the lack of labeled data (and high cost of annotation) for textual entailment in some domains. To that end, we first create (for experimental purposes) an entailment dataset for the clinical domain, and a highly…

Computation and Language · Computer Science 2016-06-09 Chaitanya Shivade , Preethi Raghavan , Siddharth Patwardhan