Related papers: An activation-clearance model for Plasmodium vivax…
To investigate the combined effects of drug resistance, seasonality and vector-bias, we formulate a periodic two-strain reaction-diffusion model. It is a competitive system for resistant and sensitive strains, but the single-strain…
A timely immunization can be effective against certain diseases and can save thousands of lives. However, for some diseases it has been difficult, so far, to develop an efficient vaccine. Malaria, a tropical disease caused by a parasite of…
Background Elimination of malaria can only be achieved through removal of all vectors or complete depletion of the infectious reservoir in humans. Mechanistic models can be built to synthesize diverse observations from the field collected…
This paper investigates the deterministic extinction and permanence of a family of SEIRS malaria models with multiple random delays, and with a general nonlinear incidence rate. The conditions for the extinction and permanence of the…
Background As more regions approach malaria elimination, understanding how different interventions interact to reduce transmission becomes critical. The Lake Kariba area of Southern Province, Zambia, is part of a multi-country elimination…
Malaria is a potentially fatal plasmodium parasite injected by female anopheles mosquitoes that infect red blood cells and millions worldwide yearly. However, specialists' manual screening in clinical practice is laborious and prone to…
We investigate a stochastic individual-based model for the population dynamics of host-virus systems where the microbial hosts may transition into a dormant state upon contact with virions, thus evading infection. Such a contact-mediated…
This research gives a thorough examination of an HIV infection model that includes quiescent cells and immune response dynamics in the host. The model, represented by a system of ordinary differential equations, captures the complex…
With over 50% of the country's population at risk of contracting malaria despite the introduction of several measures to combat the disease, Zimbabwe is one of the eight countries in the Malaria Elimination 8 platform of the Southern…
Malaria is the leading cause of death globally, especially in sub-Saharan African countries claiming over 400,000 deaths globally each year, underscoring the critical need for continued efforts to combat this preventable and treatable…
We propose a honeybee-mite-virus model that incorporates (1) parasitic interactions between honeybees and the Varroa mites; (2) five virus transmission terms between honeybees and mites at different stages of Varroa mites: from honeybees to…
Characterization of host responses associated with severe malaria through an integrative approach is necessary to understand the dynamics of a \textit{Plasmodium cynomolgi} infection. In this study, we conducted temporal immune profiling,…
Epidemiology simulations have become a fundamental tool in the fight against the epidemics of various infectious diseases like AIDS and malaria. However, the complicated and stochastic nature of these simulators can mean their output is…
It has been known for some time that human autoimmune diseases can be triggered by viral infections. Several possible mechanisms of interactions between a virus and immune system have been analysed, with a prevailing opinion being that the…
Mosquito-borne diseases remain a major public-health threat, and the effective control of mosquito populations requires sustained household participation in removing breeding sites. While environmental drivers of mosquito oscillations have…
Active movement is essential for the survival of microorganisms like bacteria, algae and unicellular parasites. In three dimensions, both swimming and gliding microorganisms often exhibit helical trajectories. One such case are malaria…
Understanding social immunity mechanisms in ant colonies remains crucial to comprehending the evolution of defense strategies in eusocial organisms. This study assumes the absence of the role of memory in the ants' defense strategy,…
Indonesia holds the second-highest-ranking country for the highest number of malaria cases in Southeast Asia. A different malaria parasite semantic segmentation technique based on a deep learning approach is an alternative to reduce the…
The emergence of cross species interactions at protein level is a part of molecular mechanisms that lead to parasitic diseases. Comprehensive modelling can capture such interactions and could be useful to understand their pathophysiology…
Broadly neutralizing antibodies are promising candidates for treatment and prevention of HIV-1 infections. Such antibodies can temporarily suppress viral load in infected individuals; however, the virus often rebounds by escape mutants that…