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In this paper we investigate the computational power of the polygonal tile assembly model (polygonal TAM) at temperature 1, i.e. in non-cooperative systems. The polygonal TAM is an extension of Winfree's abstract tile assembly model (aTAM)…

Computational Geometry · Computer Science 2015-08-20 Oscar Gilbert , Jacob Hendricks , Matthew J. Patitz , Trent A. Rogers

Patterned self-assembly tile set synthesis PATS is the problem of finding a minimal tile set which uniquely self-assembles into a given pattern. Czeizler and Popa proved the NP-completeness of PATS and Seki showed that the PATS problem is…

Computational Complexity · Computer Science 2013-06-17 Lila Kari , Steffen Kopecki , Shinnosuke Seki

Working in a three-dimensional variant of Winfree's abstract Tile Assembly Model, we show that, for all $N \in \mathbb{N}$, there is a tile set that uniquely self-assembles into an $N \times N$ square shape at temperature 1 with optimal…

Computational Geometry · Computer Science 2014-11-06 David Furcy , Samuel Micka , Scott M. Summers

Many tasks require finding groups of elements in a matrix of numbers, symbols or class likelihoods. One approach is to use efficient bi- or tri-linear factorization techniques including PCA, ICA, sparse matrix factorization and plaid…

Machine Learning · Computer Science 2012-07-02 Inmar Givoni , Vincent Cheung , Brendan J. Frey

Patterned self-assembly tile set synthesis (PATS) aims at finding a minimum tile set to uniquely self-assemble a given rectangular color pattern. For $k \ge 1$, $k$-PATS is a variant of PATS that restricts input patterns to those with at…

Computational Complexity · Computer Science 2014-04-14 Aleck C. Johnsen , Ming-Yang Kao , Shinnosuke Seki

In this paper we demonstrate the power of a model of tile self-assembly based on active glues which can dynamically change state. We formulate the Signal-passing Tile Assembly Model (STAM), based on the model of Padilla, Liu, and Seeman to…

In this paper we consider the time complexity of computing the sum and product of two $n$-bit numbers within the tile self-assembly model. The (abstract) tile assembly model is a mathematical model of self-assembly in which system…

Data Structures and Algorithms · Computer Science 2013-08-06 Alexandra Keenan , Robert Schweller , Michael Sherman , Xingsi Zhong

Branched junction molecule assembly of DNA nanostructures, pioneered by Seeman's laboratory in the 1980s, has become increasingly sophisticated, as have the assembly targets. A critical design step is finding minimal sets of branched…

Combinatorics · Mathematics 2021-08-03 Leyda Almodóvar , Jo Ellis-Monaghan , Amanda Harsy , Cory Johnson , Jessica Sorrells

Inspired by biology's most sophisticated computer, the brain, neural networks constitute a profound reformulation of computational principles. Remarkably, analogous high-dimensional, highly-interconnected computational architectures also…

Disordered Systems and Neural Networks · Physics 2024-01-23 Constantine Glen Evans , Jackson O'Brien , Erik Winfree , Arvind Murugan

We prove the computational weakness of a model of tile assembly that has so far resisted many attempts of formal analysis or positive constructions. Specifically, we prove that, in Winfree's abstract Tile Assembly Model, when restricted to…

Computational Complexity · Computer Science 2015-07-31 Pierre-Étienne Meunier , Damien Regnault

We discuss the self-assembly system of triangular tiles instead of square tiles, in particular right triangular tiles and equilateral triangular tiles. We show that the triangular tile assembly system, either deterministic or…

Discrete Mathematics · Computer Science 2010-03-01 Lila Kari , Shinnosuke Seki , Zhi Xu

Transformer models underpin many recent advances in practical machine learning applications, yet understanding their internal behavior continues to elude researchers. Given the size and complexity of these models, forming a comprehensive…

This paper introduces the theory and practice of formal verification of self-assembling systems. We interpret a well-studied abstraction of nanomolecular self assembly, the Abstract Tile Assembly Model (aTAM), into Computation Tree Logic…

Logic in Computer Science · Computer Science 2010-07-22 Aaron Sterling

Perhaps the two most significant theoretical questions about the programming of self-assembling agents are: (1) necessary and sufficient conditions to produce a unique terminal assembly, and (2) error correction. We address both questions,…

Data Structures and Algorithms · Computer Science 2009-09-16 Aaron Sterling

We show the first asymptotically efficient constructions in the so-called "noncooperative planar tile assembly" model. Algorithmic self-assembly is the study of the local, distributed, asynchronous algorithms ran by molecules to…

Computational Complexity · Computer Science 2021-07-19 Pierre-Etienne Meunier , Damien Regnault

A physically-motivated genetic algorithm (GA) and full enumeration for a tile-based model of self-assembly (JaTAM) is implemented using a graphics processing unit (GPU). We observe performance gains with respect to state-of-the-art…

Neural and Evolutionary Computing · Computer Science 2022-06-01 Christian Schroeder de Witt

As a mathematical model of self-assembling systems, Winfree's abstract Tile Assembly Model (aTAM) is a remarkable platform for studying the behaviors and powers of self-assembling systems. Capable of Turing universal computation, the aTAM…

Computational Geometry · Computer Science 2016-08-11 Jacob Hendricks , Matthew J. Patitz , Trent A. Rogers

We show that the Tile Assembly Model exhibits a strong notion of universality where the goal is to give a single tile assembly system that simulates the behavior of any other tile assembly system. We give a tile assembly system that is…

Computational Complexity · Computer Science 2016-09-08 David Doty , Jack H. Lutz , Matthew J. Patitz , Scott M. Summers , Damien Woods

Self-assembly is one of the most promising strategies for making functional materials at the nanoscale, yet new design principles for making self-limiting architectures, rather than spatially unlimited periodic lattice structures, are…

In this work we propose a generalization of Winfree's abstract Tile Assembly Model (aTAM) in which tile types are assigned rigid shapes, or geometries, along each tile face. We examine the number of distinct tile types needed to assemble…

Computational Geometry · Computer Science 2015-03-19 Bin Fu , Matthew J. Patitz , Robert T. Schweller , Bobby Sheline