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In this paper, we propose a novel data-driven approach for learning and control of quadrotor UAVs based on the Koopman operator and extended dynamic mode decomposition (EDMD). Building observables for EDMD based on conventional methods like…

Robotics · Computer Science 2024-01-12 Sriram S. K. S. Narayanan , Duvan Tellez-Castro , Sarang Sutavani , Umesh Vaidya

We present an end-to-end pipeline that converts healthcare policy documents into executable, data-aware Business Process Model and Notation (BPMN) models using large language models (LLMs) for simulation-based policy evaluation. We address…

Artificial Intelligence · Computer Science 2026-04-10 Praveen Kumar Menaka Sekar , Ion Matei , Maksym Zhenirovskyy , Hon Yung Wong , Sayuri Kohmura , Shinji Hotta , Akihiro Inomata

We develop a novel data-driven robust model predictive control (DDRMPC) approach for automatic control of irrigation systems. The fundamental idea is to integrate both mechanistic models, which describe dynamics in soil moisture variations,…

Systems and Control · Computer Science 2020-06-16 Chao Shang , Wei-Han Chen , Abraham Duncan Stroock , Fengqi You

Advanced medical devices exploit the advantages of embedded software whose development is subject to compliance with stringent requirements of standardization and certification regimes due to the critical nature of such systems. This paper…

Software Engineering · Computer Science 2017-06-21 Atif Mashkoor

Computational Fluid Dynamics (CFD) is currently used to design and improve the hydraulic properties of biomedical devices, wherein the large scale blood circulation needs to be simulated by accounting for the mechanical response of red…

Fluid Dynamics · Physics 2024-12-24 F. Guglietta , M. Behr , L. Biferale , G. Falcucci , M. Sbragaglia

Based on the driving requirement and power balance of heavy-duty vehicle equipped with Electro-Mechanical Transmission (EMT), optimization goals under different driving patterns are put forward. The optimization objectives are changed into…

Systems and Control · Electrical Eng. & Systems 2025-12-30 Yanbo Li , Jinsong Li , Zongjue Liu , Riming Xu

We analyze the asymptotic behavior of a partial differential equation (PDE) model for hematopoiesis. This PDE model is derived from the original agent-based model formulated by (Roeder et al., Nat. Med., 2006), and it describes the…

Analysis of PDEs · Mathematics 2013-01-21 Marie Doumic Jauffret , Peter S. Kim , Benoît Perthame

The Koopman operator is beneficial for analyzing nonlinear and stochastic dynamics; it is linear but infinite-dimensional, and it governs the evolution of observables. The extended dynamic mode decomposition (EDMD) is one of the famous…

Numerical Analysis · Mathematics 2022-05-18 Jun Ohkubo

Extended Dynamic Mode Decomposition (EDMD) is a data-driven tool for forecasting and model reduction of dynamics, which has been extensively taken up in the physical sciences. While the method is conceptually simple, in deterministic chaos…

Numerical Analysis · Mathematics 2024-10-18 Caroline L. Wormell

Energy-based models (EBMs) provide a powerful and flexible way of learning a joint probability distribution over data by constructing an energy surface. This energy surface enables insight extraction and conditional sampling. We apply EBMs…

Plasma Physics · Physics 2026-05-12 Phil Travis , Troy Carter

Ring polymer molecular dynamics (RPMD) is used to directly simulate the dynamics of an excess electron in a supercritical fluid over a broad range of densities. The accuracy of the RPMD model is tested against numerically exact path…

Statistical Mechanics · Physics 2011-07-27 Thomas F. Miller

Dynamic mode decomposition (DMD) is a versatile approach that enables the construction of low-order models from data. Controller design tasks based on such models require estimates and guarantees on predictive accuracy. In this work, we…

Systems and Control · Electrical Eng. & Systems 2020-03-24 Qiugang Lu , Sungho Shin , Victor M. Zavala

Erythropoiesis is a mechanism for the production of red blood cells by cellular differentiation. It is based on amplification steps due to an interplay between renewal and differentiation in the successive cell compartments from stem cells…

Probability · Mathematics 2019-12-12 Celine Bonnet , Sylvie Méléard

Objective: To improve prediction of Chronic Kidney Disease (CKD) progression to End Stage Renal Disease (ESRD) using machine learning (ML) and deep learning (DL) models applied to an integrated clinical and claims dataset of varying…

Quantitative Methods · Quantitative Biology 2025-05-06 Yubo Li , Rema Padman

Dynamic metabolic control allows key metabolic fluxes to be modulated in real time, enhancing bioprocess flexibility and expanding available optimization degrees of freedom. This is achieved, e.g., via targeted modulation of metabolic…

Systems and Control · Electrical Eng. & Systems 2025-10-03 Sebastián Espinel-Ríos , River Walser , Dongda Zhang

The metriplectic formalism is useful for describing complete dynamical systems which conserve energy and produce entropy. This creates challenges for model reduction, as the elimination of high-frequency information will generally not…

Numerical Analysis · Mathematics 2022-12-28 Anthony Gruber , Max Gunzburger , Lili Ju , Zhu Wang

This paper presents different neural network-based classifier algorithms for diagnosing and classifying Anemia. The study compares these classifiers with established models such as Feed Forward Neural Network (FFNN), Elman network, and…

Machine Learning · Computer Science 2024-04-09 Mohammed A. A. Elmaleeh

In this paper, a multi-model predictive control approach is used to automate the co-administration of propofol and remifentanil from bispectral index measurement during general anesthesia. To handle the parameter uncertainties in the…

Systems and Control · Electrical Eng. & Systems 2023-09-18 Bob Aubouin-Pairault , Mirko Fiacchini , Thao Dang

The Dynamic Mode Decomposition (DMD) is a tool of trade in computational data driven analysis of fluid flows. More generally, it is a computational device for Koopman spectral analysis of nonlinear dynamical systems, with a plethora of…

Numerical Analysis · Mathematics 2017-08-10 Zlatko Drmač , Igor Mezić , Ryan Mohr

Neutropenia is an adverse event commonly arising during intensive chemotherapy of acute myeloid leukemia (AML). It is often associated with infectious complications. Mathematical modeling, simulation, and optimization of the treatment…

Quantitative Methods · Quantitative Biology 2020-04-21 Felix Jost , Enrico Schalk , Daniela Weber , Hartmut Doehner , Thomas Fischer , Sebastian Sager