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Background and objective: Cell migration is essential for many biological phenomena with direct impact on human health and disease. One conventional approach to study cell migration involves the quantitative analysis of individual cell…

Quantitative Methods · Quantitative Biology 2023-03-14 Nirbhaya Shajia , Florbela Nunes , M. Ines Rocha , Elsa Ferreira Gomes , Helena Castro

The advancement of scientific knowledge increasingly depends on ensuring that data-driven research is reproducible: that two people with the same data obtain the same results. However, while the necessity of reproducibility is clear, there…

Computers and Society · Computer Science 2020-08-28 Audrey M. Bertin , Benjamin S. Baumer

The fitting or parameter estimation of complex ecological models is a challenging optimisation task, with a notable lack of tools for fitting complex, long runtime or stochastic models. calibrar is an R package that is dedicated to the…

Quantitative Methods · Quantitative Biology 2024-04-30 Ricardo Oliveros-Ramos , Yunne-Jai Shin

Program translation is a growing demand in software engineering. Manual program translation requires programming expertise in source and target language. One way to automate this process is to make use of the big data of programs, i.e., Big…

Software Engineering · Computer Science 2021-03-25 Binger Chen , Ziawasch Abedjan

Categories and categorical structures are increasingly recognized as useful abstractions for modeling in science and engineering. To uniformly implement category-theoretic mathematical models in software, we introduce GATlab, a…

Logic in Computer Science · Computer Science 2024-12-18 Owen Lynch , Kris Brown , James Fairbanks , Evan Patterson

OLAF (Open Life Science Analysis Framework) is an open-source platform that enables researchers to perform bioinformatics analyses using natural language. By combining large language models (LLMs) with a modular agent-pipe-router…

Quantitative Methods · Quantitative Biology 2025-04-14 Dylan Riffle , Nima Shirooni , Cody He , Manush Murali , Sovit Nayak , Rishikumar Gopalan , Diego Gonzalez Lopez

MatlabMPI is a Matlab implementation of the Message Passing Interface (MPI) standard and allows any Matlab program to exploit multiple processors. MatlabMPI currently implements the basic six functions that are the core of the MPI…

Astrophysics · Physics 2007-05-23 Jeremy Kepner

The aim of this article is to introduce a reporting framework for reproducible, interactive research applied to Big Clinical Data, based on open source technologies. The framework is constituted by the following three axes: (i) data, (ii)…

Dynamically typed programming languages like R allow programmers to write generic, flexible and concise code and to interact with the language using an interactive Read-eval-print-loop (REPL). However, this flexibility has its price: As the…

Computation · Statistics 2021-01-14 Michel Lang

Current research on large language models (LLMs) with retrieval-augmented code generation (RACG) has largely focused on single-language settings, leaving their cross-lingual effectiveness underexplored. Multilingual RACG systems are…

Software Engineering · Computer Science 2026-04-21 Qiming Zhu , Jialun Cao , Xuanang Chen , Weili Zhang , Yaojie Lu , Hongyu Lin , Xianpei Han , Le Sun , Shing-Chi Cheung

The integration of Computer-Aided Diagnosis (CAD) with Large Language Models (LLMs) presents a promising frontier in clinical applications, notably in automating diagnostic processes akin to those performed by radiologists and providing…

Computer Vision and Pattern Recognition · Computer Science 2024-05-22 Zihao Zhao , Sheng Wang , Jinchen Gu , Yitao Zhu , Lanzhuju Mei , Zixu Zhuang , Zhiming Cui , Qian Wang , Dinggang Shen

It is shown how to set up, conduct, and analyze large simulation studies with the new R package simsalapar = simulations simplified and launched parallel. A simulation study typically starts with determining a collection of input variables…

Computation · Statistics 2013-09-18 Marius Hofert , Martin Mächler

Existing LLM agents for computational materials science are constrained by pipeline-bounded architectures tied to specific simulation codes and by dependence on manually written tool functions that grow with task scope. We present MatClaw,…

Materials Science · Physics 2026-05-25 Chenmu Zhang , Boris I. Yakobson

Large Language Models (LLMs) demonstrate human-level capabilities in dialogue, reasoning, and knowledge retention. However, even the most advanced LLMs face challenges such as hallucinations and real-time updating of their knowledge.…

Computation and Language · Computer Science 2024-09-10 Xuanwang Zhang , Yunze Song , Yidong Wang , Shuyun Tang , Xinfeng Li , Zhengran Zeng , Zhen Wu , Wei Ye , Wenyuan Xu , Yue Zhang , Xinyu Dai , Shikun Zhang , Qingsong Wen

We implement a user-extensible ad hoc connection between the Lean proof assistant and the computer algebra system Mathematica. By reflecting the syntax of each system in the other and providing a flexible interface for extending…

Logic in Computer Science · Computer Science 2021-01-20 Robert Y. Lewis , Minchao Wu

RKappa is a framework for the development, simulation and analysis of rule-base models within the mature statistically empowered R environment. It is designed for model editing, parameter identification, simulation, sensitivity analysis and…

Quantitative Methods · Quantitative Biology 2018-09-24 Anatoly Sorokin , Oksana Sorokina , J. Douglas Armstrong

Following the ideas of the Remote Procedure Call model, we have developed a logic programming counterpart, naturally called Prolog Remote Predicate Call (Prolog RPC). The Prolog RPC protocol facilitates the integration of Prolog code in…

Networking and Internet Architecture · Computer Science 2007-05-23 Alin Suciu , Kalman Pusztai , Andrei Diaconu

This article introduces 'cpp11armadillo', a new R package that integrates the powerful Armadillo C++ library for linear algebra into the R programming environment. Targeted primarily at social scientists and other non-programmers, this…

Mathematical Software · Computer Science 2025-02-25 Mauricio Vargas Sepúlveda , Jonathan Schneider Malamud

I describe an approach to compiling common idioms in R code directly to native machine code and illustrate it with several examples. Not only can this yield significant performance gains, but it allows us to use new approaches to computing…

Computation · Statistics 2014-09-12 Duncan Temple Lang

In daily life, there are many scenarios that people need to tackle data-related tasks, such as filling out forms, analyzing Excel files, and visualize data report. However, the tools available for these tasks often fragment, requiring users…

Databases · Computer Science 2026-04-28 Huahang Li , Wentao Hu , Zhuoyue Wan , Chen Jason Zhang , Haoyang Li , Xiaoyong Wei