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Magnetic particle imaging (MPI) is a relatively new imaging modality. The nonlinear magnetization behavior of nanoparticles in an applied magnetic field is employed to reconstruct an image of the concentration of nanoparticles. Finding a…

Applied Physics · Physics 2018-07-04 Tobias Kluth

Magnetic particle imaging (MPI) is a tracer-based medical imaging modality that enables quantification and spatial mapping of magnetic nanoparticle (MNP) distribution. The magnetization response of MNPs depends on experimental conditions…

Signal Processing · Electrical Eng. & Systems 2025-09-03 Asli Alpman , Mustafa Utkur , Emine Ulku Saritas

Magnetic Particle Imaging (MPI) is a promising tracer-based, functional medical imaging technique which measures the non-linear magnetization response of magnetic nanoparticles to a dynamic magnetic field. For image reconstruction, system…

Image and Video Processing · Electrical Eng. & Systems 2021-08-26 Christina Brandt , Christiane Schmidt

The image reconstruction problem of the tomographic imaging technique magnetic particle imaging (MPI) requires the solution of a linear inverse problem. One prerequisite for this task is that the imaging operator that describes the mapping…

Computational Physics · Physics 2019-07-12 Tobias Kluth , Patryk Szwargulski , Tobias Knopp

Magnetic particle imaging (MPI) is a non-invasive, non-ionizing imaging technique for the visualization and quantification of magnetic nanoparticles (MNPs). The technique is especially suitable for cell imaging as it offers zero background…

In this article, we consider a model motivated by large ensembles of nanoparticles' magnetization dynamics using the Fokker-Planck equation and analyze the underlying parabolic PDE being defined on a smooth, compact manifold without…

Optimization and Control · Mathematics 2023-07-10 Hannes Albers , Tobias Kluth

Magnetic Particle Imaging (MPI) is a tomographic imaging technique for determining the spatial distribution of superparamagnetic nanoparticles. Current MPI systems are capable of imaging iron masses over a wide dynamic range of more than…

Magnetic Particle Imaging (MPI) is a novel imaging modality with important applications such as angiography, stem cell tracking, and cancer imaging. Recently, there have been efforts to increase the functionality of MPI via multi-color…

Medical Physics · Physics 2017-05-23 Yavuz Muslu , Mustafa Utkur , Omer Burak Demirel , Emine Ulku Saritas

We previously presented a lock-in-amplifier model for analyzing the behavior of signal harmonics in magnetic particle imaging (MPI). In that study, the magnetization and particle size distribution of magnetic nanoparticles (MNPs) were…

Medical Physics · Physics 2019-07-08 Kenya Murase

Magnetic Particle Imaging (MPI) is a recent imaging modality where superparamagnetic nanoparticles are employed as tracers. The reconstruction task is to obtain the spatial particle distribution from a voltage signal induced by the…

Numerical Analysis · Mathematics 2025-08-11 Thomas März , Vladyslav Gapyak , Andreas Weinmann

Magnetic nanoparticles and their magnetization dynamics play an important role in many applications. We focus on magnetization dynamics in large ensembles of single domain nanoparticles being characterized by either Brownian or N\'{e}el…

Image and Video Processing · Electrical Eng. & Systems 2020-10-16 Hannes Albers , Tobias Kluth , Tobias Knopp

Magnetic nanoparticles are useful biological probes as well as therapeutic agents. There have been several approaches used to model nanoparticle magnetization dynamics for both Brownian as well as N\'eel rotation. The magnetizations are…

Mesoscale and Nanoscale Physics · Physics 2015-05-12 Daniel B. Reeves , John B. Weaver

Magnetic particle imaging (MPI) is an imaging modality exploiting the nonlinear magnetization behavior of (super-)paramagnetic nanoparticles to obtain a space- and often also time-dependent concentration of a tracer consisting of these…

Image and Video Processing · Electrical Eng. & Systems 2020-07-06 Sören Dittmer , Tobias Kluth , Mads Thorstein Roar Henriksen , Peter Maass

Magnetic nanoparticles (MNPs) have been extensively used as contrasts and tracers for bioimaging, heating sources for tumor therapy, carriers for controlled drug delivery, and labels for magnetic immunoassays. Here, we describe a MNP…

Applied Physics · Physics 2019-09-11 Kai Wu , Jinming Liu , Diqing Su , Renata Saha , Jian-Ping Wang

Magnetic particle imaging (MPI) is a medical imaging modality of recent origin, and it exploits the nonlinear magnetization phenomenon to recover the spatially dependent concentration of the nanoparticles. Currently, image reconstruction in…

Numerical Analysis · Mathematics 2019-04-23 Tobias Kluth , Bangti Jin

Magnetic particle imaging (MPI) is a promising new in-vivo medical imaging modality in which distributions of super-paramagnetic nanoparticles are tracked based on their response in an applied magnetic field. In this paper we provide a…

Magnetic particle spectroscopy (MPS) is one of the most versatile methods to characterize the magnetic properties of magnetic nanoparticles (MNPs). The excitation magnetic field is one of the most crucial factors that affects the MPS signal…

Applied Physics · Physics 2023-04-25 Shaoqi Sun , Shijie Sun , Lijun Xu , Jing Zhong

Magnetic Particle Imaging (MPI) has been successfully used to visualize the distribution of superparamagnetic nanoparticles within 3D volumes with high sensitivity in real time. Since the magnetic field topology of MPI scanners is well…

Magnetic nanoparticles (MNPs) have been proposed as an ultimate solution for diverse applications including nanomedicine and logic devices over decades. However, none has emerged revolutionary because realizing their magnetization response…

Applied Physics · Physics 2020-02-19 Mohammad Reza Zamani Kouhpanji , Pieter B Visscher , Bethanie J H Stadler

Brownian relaxation is one of the primary mechanisms that allows magnetic nanoparticles (MNPs) to convert magnetic energy into thermal energy under an excitation magnetic field. Accurately characterizing the MNPs' magnetization dynamics…

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