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We propose two methods to evaluate the conditional Akaike information (cAI) for nonlinear mixed-effects models with no restriction on cluster size. Method 1 is designed for continuous data and includes formulae for the derivatives of fixed…

Methodology · Statistics 2024-11-22 Nan Zheng , Noel Cadigan , James T. Thorson

Foundation models often generate unreliable answers, while heuristic uncertainty estimators fail to fully distinguish correct from incorrect outputs, causing users to accept erroneous answers without any statistical guarantee. We address…

Artificial Intelligence · Computer Science 2026-05-27 Zhiyuan Wang , Aniri , Tianlong Chen , Yue Zhang , Heng Tao Shen , Xiaoshuang Shi , Kaidi Xu

We propose a new model selection criterion for mixed effects regression models that is computable when the model is fitted with a two-step method, even when the structure and the distribution of the random effects are unknown. The criterion…

Methodology · Statistics 2018-03-14 Radu V. Craiu , Thierry Duchesne

Learning graphical conditional independence structures from nonlinear, continuous or mixed data is a central challenge in machine learning and the sciences, and many existing methods struggle to scale to thousands of samples or hundreds of…

Machine Learning · Statistics 2025-11-05 Joseph Ramsey , Bryan Andrews , Peter Spirtes

Weighting methods in causal inference have been widely used to achieve a desirable level of covariate balancing. However, the existing weighting methods have desirable theoretical properties only when a certain model, either the propensity…

Machine Learning · Statistics 2023-05-24 Insung Kong , Yuha Park , Joonhyuk Jung , Kwonsang Lee , Yongdai Kim

High-dimensional categorical data arise in diverse scientific domains and are often accompanied by covariates. Latent class regression models are routinely used in such settings, reducing dimensionality by assuming conditional independence…

Methodology · Statistics 2026-05-28 Yuren Zhou , Yuqi Gu , David B. Dunson

Instrumental variable methods allow for inference about the treatment effect by controlling for unmeasured confounding in randomized experiments with noncompliance. However, many studies do not consider the observed compliance behavior in…

Methodology · Statistics 2020-06-15 Kwonsang Lee , Bhaswar B. Bhattacharya , Jing Qin , Dylan S. Small

Conditional Mutual Information (CMI) is a measure of conditional dependence between random variables X and Y, given another random variable Z. It can be used to quantify conditional dependence among variables in many data-driven inference…

Machine Learning · Computer Science 2019-06-10 Sudipto Mukherjee , Himanshu Asnani , Sreeram Kannan

The paper obtains analytical results for the asymptotic properties of Model Selection Criteria -- widely used in practice -- for a general family of hidden Markov models (HMMs), thereby substantially extending the related theory beyond…

Statistics Theory · Mathematics 2022-07-04 Shouto Yonekura , Alexandros Beskos , Sumeetpal S. Singh

Multiple imputation provides an effective way to handle missing data. When several possible models are under consideration for the data, the multiple imputation is typically performed under a single-best model selected from the candidate…

Methodology · Statistics 2018-11-30 Gyuhyeong Goh , Jae Kwang Kim

Empirical likelihood is a popular nonparametric statistical tool that does not require any distributional assumptions. In this paper, we explore the possibility of conducting variable selection via Bayesian empirical likelihood. We show…

Methodology · Statistics 2022-06-13 Yichen Cheng , Yichuan Zhao

We have recently proposed a new information-based approach to model selection, the Frequentist Information Criterion (FIC), that reconciles information-based and frequentist inference. The purpose of this current paper is to provide a…

Data Analysis, Statistics and Probability · Physics 2015-06-23 Paul A. Wiggins

We consider constructing model selection criteria for evaluating nonlinear mixed effects models via basis expansions. Mean functions and random functions in the mixed effects model are expressed by basis expansions, then they are estimated…

Methodology · Statistics 2014-02-25 Hidetoshi Matsui

Data-driven model discovery (DDMD) algorithms are powerful tools for extracting interpretable symbolic models from data. However, identifying the model that best balances goodness-of-fit and sparsity is often a laborious process requiring…

Quantitative Methods · Quantitative Biology 2026-02-26 Michael C Chung , Alen Zacharia , Juan Guan

Penalized logistic regression methods are frequently used to investigate the relationship between a binary outcome and a set of explanatory variables. The model performance can be assessed by measures such as the concordance statistic…

Methodology · Statistics 2021-01-20 Angelika Geroldinger , Lara Lusa , Mariana Nold , Georg Heinze

Restricted maximum likelihood (REML) estimation is a widely accepted and frequently used method for fitting linear mixed models, with its principal advantage being that it produces less biased estimates of the variance components. However,…

Methodology · Statistics 2025-05-15 Luca Maestrini , Francis K. C. Hui , Alan H. Welsh

We propose a robust variable selection procedure using a divergence based M-estimator combined with a penalty function. It produces robust estimates of the regression parameters and simultaneously selects the important explanatory…

Methodology · Statistics 2020-01-01 Abhijit Mandal , Samiran Ghosh

Micro-randomized trials are commonly conducted for optimizing mobile health interventions such as push notifications for behavior change. In analyzing such trials, causal excursion effects are often of primary interest, and their estimation…

Methodology · Statistics 2024-08-19 Yihan Bao , Lauren Bell , Elizabeth Williamson , Claire Garnett , Tianchen Qian

In biometrics and related fields, the Cox proportional hazards model are widely used to analyze with covariate adjustment. However, when some covariates are not observed, an unbiased estimator usually cannot be obtained. Even if there are…

Methodology · Statistics 2022-06-06 Shunichiro Orihara

We develop an empirical Bayes procedure for estimating the cell means in an unbalanced, two-way additive model with fixed effects. We employ a hierarchical model, which reflects exchangeability of the effects within treatment and within…

Methodology · Statistics 2016-05-30 Lawrence D. Brown , Gourab Mukherjee , Asaf Weinstein