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Analyzing large datasets to select optimal features is one of the most important research areas in machine learning and data mining. This feature selection procedure involves dimensionality reduction which is crucial in enhancing the…
The XGBoost method has many advantages and is especially suitable for statistical analysis of big data, but its loss function is limited to convex functions. In many specific applications, a nonconvex loss function would be preferable. In…
Random Forests have been one of the most popular bagging methods in the past few decades, especially due to their success at handling tabular datasets. They have been extensively studied and compared to boosting models, like XGBoost, which…
Optimal subset selection is an important task that has numerous algorithms designed for it and has many application areas. STPGA contains a special genetic algorithm supplemented with a tabu memory property (that keeps track of previously…
With the rapid evolution of large language models, retrieval enhanced generation technology has been widely used due to its ability to integrate external knowledge to improve output accuracy. However, the performance of the system is highly…
Lung cancer is among the most common cancers in the United States, in terms of incidence and mortality. In 2009, it is estimated that more than 150,000 deaths will result from lung cancer alone. Genetic information is an extremely valuable…
In cancer research, high-throughput profiling has been extensively conducted. In recent studies, the integrative analysis of data on multiple cancer patient groups/subgroups has been conducted. Such analysis has the potential to reveal the…
This work proposes a novel portfolio management technique, the Meta Portfolio Method (MPM), inspired by the successes of meta approaches in the field of bioinformatics and elsewhere. The MPM uses XGBoost to learn how to switch between two…
Optimal Mixing (OM) is a variation operator that integrates local search with genetic recombination. EAs with OM are capable of state-of-the-art optimization in discrete spaces, offering significant advantages over classic…
Biomedical data is filled with continuous real values; these values in the feature set tend to create problems like underfitting, the curse of dimensionality and increase in misclassification rate because of higher variance. In response,…
It is increasingly common clinically for cancer specimens to be examined using techniques that identify somatic mutations. In principle these mutational profiles can be used to diagnose the tissue of origin, a critical task for the 3-5% of…
Class imbalance classification is a challenging research problem in data mining and machine learning, as most of the real-life datasets are often imbalanced in nature. Existing learning algorithms maximise the classification accuracy by…
Accurately predicting early recurrence in brain tumor patients following surgical resection remains a clinical challenge. This study proposes a multi-modal machine learning framework that integrates structural MRI features with clinical…
This paper compares the performance of various data processing methods in terms of predictive performance for structured data. This paper also seeks to identify and recommend preprocessing methodologies for tree-based binary classification…
Brain tumors pose a serious health threat due to their rapid growth and potential for metastasis. While medical imaging has advanced significantly, accurately identifying and characterizing these tumors remains a challenge. This study…
Statistical learning methods for automated variable selection, such as the Least Absolute Shrinkage and Selection Operator (LASSO), elastic nets, and gradient boosting, have become increasingly popular tools for building powerful prediction…
This study evaluates the performance of various supervised machine learning models in analyzing highly correlated neural signaling data from the Adolescent Brain Cognitive Development (ABCD) Study, with a focus on predicting…
Deep learning has become the mainstream methodological choice for analyzing and interpreting whole-slide digital pathology images (WSIs). It is commonly assumed that tumor regions carry most predictive information. In this paper, we…
Multi-modal learning plays a crucial role in cancer diagnosis and prognosis. Current deep learning based multi-modal approaches are often limited by their abilities to model the complex correlations between genomics and histology data,…
In petroleum engineering, it is essential to determine the ultimate recovery factor, RF, particularly before exploitation and exploration. However, accurately estimating requires data that is not necessarily available or measured at early…