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Motivation: Gene selection has become a common task in most gene expression studies. The objective of such research is often to identify the smallest possible set of genes that can still achieve good predictive performance. The problem of…

A feature selection algorithm should ideally satisfy four conditions: reliably extract relevant features; be able to identify non-linear feature interactions; scale linearly with the number of features and dimensions; allow the…

Machine Learning · Computer Science 2019-01-15 Zhixiang Eddie Xu , Gao Huang , Kilian Q. Weinberger , Alice X. Zheng

This paper presents a theory and an empirical evaluation of Higher-Order Quantum-Inspired Genetic Algorithms. Fundamental notions of the theory have been introduced, and a novel Order-2 Quantum-Inspired Genetic Algorithm (QIGA2) has been…

Neural and Evolutionary Computing · Computer Science 2014-07-04 Robert Nowotniak , Jacek Kucharski

Gene expression profiles obtained through DNA microarray have proven successful in providing critical information for cancer detection classifiers. However, the limited number of samples in these datasets poses a challenge to employ complex…

Machine Learning · Computer Science 2024-08-20 Arya Hadizadeh Moghaddam , Mohsen Nayebi Kerdabadi , Cuncong Zhong , Zijun Yao

Due to the advantage of achieving a better performance under weak regularization, elastic net has attracted wide attention in statistics, machine learning, bioinformatics, and other fields. In particular, a variation of the elastic net,…

Machine Learning · Statistics 2018-06-14 Xin-Guang Yang , Yongjin Lu

Microarray technology is a process that allows thousands of genes simultaneously monitor to various experimental conditions. It is used to identify the co-expressed genes in specific cells or tissues that are actively used to make proteins,…

Computational Engineering, Finance, and Science · Computer Science 2013-07-16 T. Chandrasekhar , K. Thangavel , E. Elayaraja

Introduction: Feature selection and gene set analysis are of increasing interest in bioinformatics. While these two approaches have been developed for different purposes, we describe how some gene set analysis methods can be used to conduct…

Methodology · Statistics 2015-11-30 Suyan Tian , Chi Wang , Howard H. Chang

Breast cancer has long been a prominent cause of mortality among women. Diagnosis, therapy, and prognosis are now possible, thanks to the availability of RNA sequencing tools capable of recording gene expression data. Molecular subtyping…

Machine Learning · Computer Science 2021-11-11 Sheetal Rajpal , Virendra Kumar , Manoj Agarwal , Naveen Kumar

Studies have shown that multi-objective optimization problems are hard problems. Such problems either require longer time to converge to an optimum solution, or may not converge at all. Recently some researchers have claimed that real…

Neural and Evolutionary Computing · Computer Science 2014-06-11 Shahab U. Ansari , Sameen Mansha

We extend the standard rough set-based approach to deal with huge amounts of numeric attributes versus small amount of available objects. Here, a novel approach of clustering along with dimensionality reduction; Hybrid Fuzzy C Means-Quick…

Computational Engineering, Finance, and Science · Computer Science 2013-06-11 E. N. Sathishkumar , K. Thangavel , T. Chandrasekhar

The MUST (Mass Unspecific Supervised Tagging) method has proven to be successful in implementing generic jet taggers capable of discriminating various signals over a wide range of jet masses. We implement the MUST concept by using eXtreme…

High Energy Physics - Phenomenology · Physics 2024-11-26 J. A. Aguilar-Saavedra , E. Arganda , F. R. Joaquim , R. M. Sandá Seoane , J. F. Seabra

Training a classification model on a dataset where the instances of one class outnumber those of the other class is a challenging problem. Such imbalanced datasets are standard in real-world situations such as fraud detection, medical…

Machine Learning · Computer Science 2020-09-04 Anubha Kabra , Ayush Chopra , Nikaash Puri , Pinkesh Badjatiya , Sukriti Verma , Piyush Gupta , Balaji K

Personalized medicine is expected to maximize the intended drug effects and minimize side effects by treating patients based on their genetic profiles. Thus, it is important to generate drugs based on the genetic profiles of diseases,…

Machine Learning · Computer Science 2021-12-17 Sejin Park , Hyunju Lee

The prediction plays the important role in detecting efficient protection and therapy of cancer. The prediction of mutations in gene needs a diagnostic and classification, which is based on the whole database (big dataset), to reach…

Machine Learning · Computer Science 2016-08-10 Ayad Ghany Ismaeel , Dina Yousif Mikhail

Feature selection has always been a critical step in pattern recognition, in which evolutionary algorithms, such as the genetic algorithm (GA), are most commonly used. However, the individual encoding scheme used in various GAs would either…

Machine Learning · Computer Science 2017-05-01 Benteng Ma , Yong Xia

Gene expression analysis is a critical method for cancer classification, enabling precise diagnoses through the identification of unique molecular signatures associated with various tumors. Identifying cancer-specific genes from gene…

Quantitative Methods · Quantitative Biology 2024-10-11 Farzana Tabassum , Sabrina Islam , Siana Rizwan , Masrur Sobhan , Tasnim Ahmed , Sabbir Ahmed , Tareque Mohmud Chowdhury

Recently, a number of competitive methods have tackled unsupervised representation learning by maximising the mutual information between the representations produced from augmentations. The resulting representations are then invariant to…

Computer Vision and Pattern Recognition · Computer Science 2020-03-20 Luke Nicholas Darlow , Amos Storkey

This study examines the effect that different feature selection methods have on models created with XGBoost, a popular machine learning algorithm with superb regularization methods. It shows that three different ways for reducing the…

Machine Learning · Computer Science 2024-11-12 Jorge Neyra , Vishal B. Siramshetty , Huthaifa I. Ashqar

Despite the rise to dominance of deep learning in unstructured data domains, tree-based methods such as Random Forests (RF) and Gradient Boosted Decision Trees (GBDT) are still the workhorses for handling discriminative tasks on tabular…

Machine Learning · Computer Science 2025-04-21 João Bravo

In the biclustering problem, we seek to simultaneously group observations and features. While biclustering has applications in a wide array of domains, ranging from text mining to collaborative filtering, the problem of identifying…

Methodology · Statistics 2018-06-07 Eric C. Chi , Genevera I. Allen , Richard G. Baraniuk
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