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Flagella of eukaryotic cells are transient long cylindrical protrusions. The proteins needed to form and maintain flagella are synthesized in the cell body and transported to the distal tips. What `rulers' or `timers' a specific type of…

Biological Physics · Physics 2021-08-31 Swayamshree Patra , Frank Jülicher , Debashish Chowdhury

Understanding the fluctuations of observables is one of the main goals in science, be it theoretical or experimental, quantum or classical. We investigate such fluctuations when only a subregion of the full system can be observed, focusing…

Strongly Correlated Electrons · Physics 2022-02-02 Benoit Estienne , Jean-Marie Stéphan , William Witczak-Krempa

Bacteria are highly adaptive microorganisms that thrive in a wide range of growth conditions via changes in cell morphologies and macromolecular composition. How bacterial morphologies are regulated in diverse environmental conditions is a…

Cell Behavior · Quantitative Biology 2021-10-26 Diana Serbanescu , Nikola Ojkic , Shiladitya Banerjee

How cells maintain a stable size has fascinated scientists since the beginning of modern biology, but has remained largely mysterious. Recently, however, the ability to analyze single bacteria in real time has provided new, important…

Cell Behavior · Quantitative Biology 2015-04-02 Suckjoon Jun , Sattar Taheri-Araghi

All types of blood cells are formed by differentiation from a small self-maintaining population of pluri-potential stem cells in the bone marrow. Despite abundant information on the molecular aspects of division, differentiation, commitment…

Biological Physics · Physics 2007-05-23 Carlos A. Perazzo , Elmer A. Fernandez , Dante R. Chialvo , Peter Willshaw

We theoretically investigate the membrane fluctuations of red blood cells with focus laid on the role of the cytoskeleton, viewing the system as a membrane coupled to sparse spring network. This model is exactly solvable and enables us to…

Soft Condensed Matter · Physics 2015-08-31 Wonjune Choi , Juyeon Yi , Yong Woon Kim

An approach is suggested for treating multiscale fluctuations in macromolecular systems. The emphasis is on the statistical properties of such fluctuations. The approach is illustrated by a macromolecular system with mesoscopic fluctuations…

Chemical Physics · Physics 2012-08-07 V. I. Yukalov , E. P. Yukalova

Motile eukaryotic cells propel themselves in viscous fluids by passing waves of bending deformation down their flagella. An infinitely long flagellum achieves a hydrodynamically optimal low-Reynolds number locomotion when the angle between…

Biological Physics · Physics 2010-03-03 Saverio E. Spagnolie , Eric Lauga

Practical methods for quantitative analysis of radial and angular coordinates of leafy organs of vascular plants are presented and applied to published phyllotactic patterns of various real systems from young leaves on a shoot tip to…

Biological Physics · Physics 2012-12-17 Takuya Okabe

The mean size of exponentially dividing E. coli cells cultured in different nutrient conditions is known to depend on the mean growth rate only. However, the joint fluctuations relating cell size, doubling time and individual growth rate…

The mechanism by which cells measure the dimension of the organ in which they are embedded, and slow down their growth when the final size is reached, is a long-standing problem of developmental biology. The role of mechanics in this…

Biological Physics · Physics 2023-07-19 Alexander Erlich , Pierre Recho

We measure different contributions to entropy production in a living functional epithelial tissue. We do this by extracting the functional dynamics of development while at the same time quantifying fluctuations. Using the translucent…

Soft Condensed Matter · Physics 2023-01-25 Mark Olenik , Jake Turley , Stephen Cross , Helen Weavers , Paul Martin , Isaac Chenchiah , Tanniemola Liverpool

Swimming eukaryotic microorganisms such as spermatozoa, algae and ciliates self-propel in viscous fluids using travelling wave-like deformations of slender appendages called flagella. Waves are predominant because Purcell's scallop theorem…

Fluid Dynamics · Physics 2020-11-18 Eric Lauga

The adaptive immune system relies on the diversity of receptors expressed on the surface of B and T-cells to protect the organism from a vast amount of pathogenic threats. The proliferation and degradation dynamics of different cell types…

Populations and Evolution · Quantitative Biology 2016-02-10 Jonathan Desponds , Thierry Mora , Aleksandra M. Walczak

By analyzing the movements of quiet standing persons by means of wavelet statistics, we observe multiple scaling regions in the underlying body dynamics. The use of the wavelet-variance function opens the possibility to relate scaling…

Biological Physics · Physics 2009-11-06 S. Thurner , C. Mittermaier , R. Hanel , K. Ehrenberger

Mathematical and computational models can assist in gaining an understanding of cell behavior at many levels of organization. Here, we review models in the literature that focus on eukaryotic cell motility at 3 size scales: intracellular…

Cell Behavior · Quantitative Biology 2021-01-27 Andreas Buttenschön , Leah Edelstein-Keshet

Growth-fragmentation processes model systems of cells that grow continuously over time and then fragment into smaller pieces. Typically, on average, the number of cells in the system exhibits asynchronous exponential growth and, upon…

Probability · Mathematics 2023-06-08 Emma Horton , Alexander R. Watson

Many biological microorganisms and artificial microswimmers react to external cues of environmental gradients by changing their swimming directions. We study here the behavior of eukarytic flagellated microswimmers in linear viscosity…

Soft Condensed Matter · Physics 2026-05-29 Shubham Anand , Jens Elgeti , Gerhard Gompper

In stable environments, cell size fluctuations are thought to be governed by simple physical principles, as suggested by recent findings of scaling properties. Here, by developing a microfluidic device and using E. coli, we investigate the…

Cell Behavior · Quantitative Biology 2021-11-12 Takuro Shimaya , Reiko Okura , Yuichi Wakamoto , Kazumasa A. Takeuchi

Cells control their size to cope with noise during growth and division. Eukaryotic cells exhibiting "sizer" control (targeting a specific size before dividing) may rely on molecular concentration thresholds, but simple implementations of…

Biological Physics · Physics 2026-05-08 Motasem ElGamel , Lucas Ribaudo , Andrew Mugler