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High-stakes synthetic data generation faces a fundamental Quadrilemma: achieving Fidelity to the original distribution, Control over complex logical constraints, Reliability in uncertainty estimation, and Efficiency in computational cost --…

Machine Learning · Computer Science 2026-03-05 Taha Racicot

Inverse design of heterogeneous material microstructures is a fundamentally ill-posed and famously computationally expensive problem. This is exacerbated by the high-dimensional design spaces associated with finely resolved images,…

Machine Learning · Computer Science 2026-03-17 Reza T. Batley , Sourav Saha

A genetic algorithm is suitable for exploring large search spaces as it finds an approximate solution. Because of this advantage, genetic algorithm is effective in exploring vast and unknown space such as molecular search space. Though the…

Neural and Evolutionary Computing · Computer Science 2021-12-24 Yurim Lee , Gydam Choi , Minsung Yoon , Cheongwon Kim

Neural architecture search (NAS), the study of automating the discovery of optimal deep neural network architectures for tasks in domains such as computer vision and natural language processing, has seen rapid growth in the machine learning…

Neural and Evolutionary Computing · Computer Science 2022-03-01 Daniel Cummings , Sharath Nittur Sridhar , Anthony Sarah , Maciej Szankin

Understanding how nano- or micro-scale structures and material properties can be optimally configured to attain specific functionalities remains a fundamental challenge. Photonic metasurfaces, for instance, can be spectrally tuned through…

The challenge of discovering new molecules with desired properties is crucial in domains like drug discovery and material design. Recent advances in deep learning-based generative methods have shown promise but face the issue of sample…

Biomolecules · Quantitative Biology 2024-12-31 Hyeonah Kim , Minsu Kim , Sanghyeok Choi , Jinkyoo Park

This paper describes JANUS, a modular massively parallel and reconfigurable FPGA-based computing system. Each JANUS module has a computational core and a host. The computational core is a 4x4 array of FPGA-based processing elements with…

Challenges in natural sciences can often be phrased as optimization problems. Machine learning techniques have recently been applied to solve such problems. One example in chemistry is the design of tailor-made organic materials and…

Neural and Evolutionary Computing · Computer Science 2020-01-17 AkshatKumar Nigam , Pascal Friederich , Mario Krenn , Alán Aspuru-Guzik

We develop a Genetic Programming-based methodology that enables discovery of novel functional forms for classical inter-atomic force-fields, used in molecular dynamics simulations. Unlike previous efforts in the field, that fit only the…

Neural and Evolutionary Computing · Computer Science 2007-05-23 A. Slepoy , A. P. Thompson , M. D. Peters

Neural architecture search (NAS) has emerged as a powerful paradigm that enables researchers to automatically explore vast search spaces and discover efficient neural networks. However, NAS suffers from a critical bottleneck, i.e. the…

Neural and Evolutionary Computing · Computer Science 2026-01-05 Yu Xue , Pengcheng Jiang , Chenchen Zhu , MengChu Zhou , Mohamed Wahib , Moncef Gabbouj

Recently, deep neural networks (DNNs) have shown advantages in accelerating optimization algorithms. One approach is to unfold finite number of iterations of conventional optimization algorithms and to learn parameters in the algorithms.…

Machine Learning · Computer Science 2021-04-23 Byung Hyun Lee , Se Young Chun

Optimizing a neural network's performance is a tedious and time taking process, this iterative process does not have any defined solution which can work for all the problems. Optimization can be roughly categorized into - Architecture and…

Machine Learning · Computer Science 2019-12-16 Siddhartha Dhar Choudhury , Shashank Pandey , Kunal Mehrotra

In machine learning and molecular design, there exist two approaches: discriminative and generative. In the discriminative approach dubbed forward design, the goal is to map a set of features/molecules to their respective electronics…

Chemical Physics · Physics 2019-04-24 Alain Tchagang , Julio Valdés

Conjugated organic molecules represent an important area of materials chemistry for both fundamental scientific exploration and technological applications. Using a genetic algorithm to computationally screen up to ~25-50 million molecules…

Applied Physics · Physics 2017-07-14 Ilana Y. Kanal , Geoffrey R. Hutchison

We propose the use of the parallel tabu search algorithm (PTS) to solve combinatorial inverse design problems in integrated photonics. To assess the potential of this algorithm, we consider the problem of beam shaping using a…

Optics · Physics 2013-06-19 Denis Gagnon , Joey Dumont , Louis J. Dubé

We present a multi-purpose genetic algorithm, designed and implemented with GPGPU / CUDA parallel computing technology. The model was derived from a multi-core CPU serial implementation, named GAME, already scientifically successfully…

Instrumentation and Methods for Astrophysics · Physics 2015-01-30 Stefano Cavuoti , Mauro Garofalo , Massimo Brescia , Antonio Pescapé , Giuseppe Longo , Giorgio Ventre

When employing an evolutionary algorithm to optimize a neural networks architecture, developers face the added challenge of tuning the evolutionary algorithm's own hyperparameters - population size, mutation rate, cloning rate, and number…

Neural and Evolutionary Computing · Computer Science 2025-03-17 Benjamin David Winter , William J. Teahan

We introduce a novel technique for designing color filter metasurfaces using a data-driven approach based on deep learning. Our innovative approach employs inverse design principles to identify highly efficient designs that outperform all…

Many evolutionary algorithms (EAs) take advantage of parallel evaluation of candidates. However, if evaluation times vary significantly, many worker nodes (i.e.,\ compute clients) are idle much of the time, waiting for the next generation…

Neural and Evolutionary Computing · Computer Science 2024-01-02 Jason Liang , Hormoz Shahrzad , Risto Miikkulainen

Metasurfaces are subwavelength-structured artificial media that can shape and localize electromagnetic waves in unique ways. The inverse design of these devices is a non-convex optimization problem in a high dimensional space, making global…

Computational Physics · Physics 2019-11-22 Jiaqi Jiang , Jonathan A. Fan
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