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Ultrasound computed tomography (USCT) is an emerging modality for breast imaging. Image reconstruction methods that incorporate accurate wave physics produce high resolution quantitative images of acoustic properties but are computationally…

Image and Video Processing · Electrical Eng. & Systems 2025-02-14 Luke Lozenski , Hanchen Wang , Fu Li , Mark A. Anastasio , Brendt Wohlberg , Youzuo Lin , Umberto Villa

Optoacoustic tomography (OAT) is a promising modality for breast cancer diagnosis because tumor angiogenesis and, potentially, hypoxia can be visualized using quantitative OAT (qOAT) techniques. Clinically meaningful inference generally…

Medical Physics · Physics 2025-10-02 Seonyeong Park , Gangwon Jeong , Umberto Villa , Mark A. Anastasio

Breast cancer is the most prevalent cancer with a high mortality rate in women over the age of 40. Many studies have shown that the detection of cancer at earlier stages significantly reduces patients' mortality and morbidity rages.…

Image and Video Processing · Electrical Eng. & Systems 2023-05-01 Takumi Noda , Yuu Jinnai , Naoki Tomii , Takashi Azuma

An alternative approach to ultrasound computed tomography (USCT) for medical imaging is proposed, with the intent to (i) shorten acquisition time for devices with a large number of emitters, (ii) eliminate the calibration step, and (iii)…

Medical Physics · Physics 2022-01-25 Ines Elisa Ulrich , Christian Boehm , Andrea Zunino , Cyrill Bösch , Andreas Fichtner

Ultrasound Computed Tomography (USCT) has great potential for 3D quantitative imaging of acoustic breast tissue properties. Typical devices include high-frequency transducers, which makes tomography techniques based on numerical wave…

Medical Physics · Physics 2019-08-12 N. Korta Martiartu , C. Boehm , A. Fichtner

Transcranial photoacoustic computed tomography (PACT) is an emerging neuroimaging modality, but skull-induced aberrations can result in severe image artifacts if not compensated for during image reconstruction. The development of advanced…

Purpose: Digital phantoms are one of the key components of virtual imaging trials (VITs) that aim to assess and optimize new medical imaging systems and algorithms. However, these phantoms vary in their voxel resolution, appearance, and…

Medical Physics · Physics 2024-02-02 Amar Kavuri , Mini Das

Ultrasound computed tomography (USCT) is a promising technique that achieves superior medical imaging reconstruction resolution by fully leveraging waveform information, outperforming conventional ultrasound methods. Despite its advantages,…

Image and Video Processing · Electrical Eng. & Systems 2024-07-23 Yi Sheng , Hanchen Wang , Yipei Liu , Junhuan Yang , Weiwen Jiang , Youzuo Lin , Lei Yang

Ultrasound computed tomography (USCT) is an emerging medical imaging modality that holds great promise for improving human health. Full-waveform inversion (FWI)-based image reconstruction methods account for the relevant wave physics to…

Medical Physics · Physics 2023-10-20 Fu Li , Umberto Villa , Nebojsa Duric , Mark A. Anastasio

Virtual Imaging Trials (VIT) offer a cost-effective and scalable approach for evaluating medical imaging technologies. Computational phantoms, which mimic real patient anatomy and physiology, play a central role in VITs. However, the…

Fluorescence molecular tomography (FMT) has potential of providing high contrast images for breast tumor detection. Computational phantom provides a convenient way to a wide variety of fluorophore distribution configurations in patients and…

Medical Physics · Physics 2018-04-02 Yansong Zhu , Abhinav K. Jha , Arman Rahmim

Objectives: Computerized phantoms play an essential role in various applications of medical imaging research. Although the existing computerized phantoms can model anatomical variations through organ and phantom scaling, this does not…

Image and Video Processing · Electrical Eng. & Systems 2021-04-20 Junyu Chen , Ye Li , Yong Du , Eric C. Frey

Medical imaging phantoms are widely used for validation and verification of imaging systems and algorithms in surgical guidance and radiation oncology procedures. Especially, for the performance evaluation of new algorithms in the field of…

The framework of ultrasound computed tomography (USCT) has recently re-emerged as a powerful, safe and operator-independent way to image the breast. State of the art image reconstruction methods are performed with iterative techniques based…

Medical Physics · Physics 2025-08-13 Luca A. Forte

Accurate and efficient simulation of wave equations is crucial in computational wave imaging applications, such as ultrasound computed tomography (USCT), which reconstructs tissue material properties from observed scattered waves.…

Computer Vision and Pattern Recognition · Computer Science 2025-07-22 Zhijun Zeng , Youjia Zheng , Hao Hu , Zeyuan Dong , Yihang Zheng , Xinliang Liu , Jinzhuo Wang , Zuoqiang Shi , Linfeng Zhang , Yubing Li , He Sun

Quantitative photoacoustic computed tomography (qPACT) is a promising imaging modality for estimating physiological parameters such as blood oxygen saturation. However, developing robust qPACT reconstruction methods remains challenging due…

Medical Physics · Physics 2025-10-07 Refik Mert Cam , Seonyeong Park , Umberto Villa , Mark A. Anastasio

Photoacoustic computed tomography (PACT) is a hybrid imaging modality, which combines the high optical contrast of pure optical imaging and the high penetration depth of ultrasound imaging. However, photoacoustic image dataset with good…

Medical Physics · Physics 2022-05-24 Tengbo Lyu , Changchun Yang , Jiadong Zhang , Shanshan Guo , Feng Gao , Fei Gao

Objective evaluation of new and improved methods for PET imaging requires access to images with ground truth, as can be obtained through simulation studies. However, for these studies to be clinically relevant, it is important that the…

Photoacoustic tomography (PAT) is a newly developed medical imaging modality, which combines the advantages of pure optical imaging and ultrasound imaging, owning both high optical contrast and deep penetration depth. Very recently, PAT is…

Medical Physics · Physics 2021-09-21 Tengbo Lyu , Jiadong Zhang , Zijian Gao , Changchun Yang , Feng Gao , Fei Gao

Prostate cancer is a major global health concern, requiring advancements in robotic surgery and diagnostics to improve patient outcomes. A phantom is a specially designed object that simulates human tissues or organs. It can be used for…

Medical Physics · Physics 2025-08-25 Sizhe Tian , Yinoussa Adagolodjo , Jeremie Dequidt
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