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We develop a Bayesian bivariate spatial model for multivariate regression analysis applicable to studies examining the influence of genetic variation on brain structure. Our model is motivated by an imaging genetics study of the Alzheimer's…

Methodology · Statistics 2020-05-26 Yin Song , Shufei Ge , Jiguo Cao , Liangliang Wang , Farouk S. Nathoo

Neuroradiologists and neurosurgeons increasingly opt to use functional magnetic resonance imaging (fMRI) to map functionally relevant brain regions for noninvasive presurgical planning and intraoperative neuronavigation. This application…

Methodology · Statistics 2023-06-07 Andrew S. Whiteman , Andreas J. Bartsch , Jian Kang , Timothy D. Johnson

Brain imaging plays a crucial role in the diagnosis and treatment of various neurological disorders, providing valuable insights into the structure and function of the brain. Techniques such as magnetic resonance imaging (MRI) and computed…

Image and Video Processing · Electrical Eng. & Systems 2025-01-23 Fatima Haimour , Rizik Al-Sayyed , Waleed Mahafza , Omar S. Al-Kadi

For sequentially observed functional data exhibiting multiple change points in the mean function, we establish consistency results for the estimated number and locations of the change points based on the norm of the functional CUSUM process…

Statistics Theory · Mathematics 2020-01-03 Gregory Rice , Chi Zhang

Open gantry C-arm systems that are placed within the interventional room enable 3-D imaging and guidance for stroke therapy without patient transfer. This can profit in drastically reduced time-totherapy, however, due to the interventional…

Structural and functional neuroimaging modalities provide complementary windows into brain organization: structural imaging characterizes neural tissue anatomy and microstructure, while functional imaging captures dynamic patterns of neural…

Methodology · Statistics 2026-03-24 Sakul Mahat , Sharmistha Guha , Jessica Bernard

Structural covariance analysis is a widely used structural MRI analysis method which characterises the co-relations of morphology between brain regions over a group of subjects. To our knowledge, little has been investigated in terms of the…

Neurons and Cognition · Quantitative Biology 2020-06-01 Jona Carmon , Jil Heege , Joe H Necus , Thomas W Owen , Gordon Pipa , Marcus Kaiser , Peter N Taylor , Yujiang Wang

The volume estimation of brain regions from MRI data is a key problem in many clinical applications, where the acquisition of data at high spatial resolution is desirable. While parallel MRI and constrained image reconstruction algorithms…

Image and Video Processing · Electrical Eng. & Systems 2021-05-20 Aniket Pramanik , Xiaodong Wu , Mathews Jacob

Multimodal image fusion aims to combine relevant information from images acquired with different sensors. In medical imaging, fused images play an essential role in both standard and automated diagnosis. In this paper, we propose a novel…

Computer Vision and Pattern Recognition · Computer Science 2021-02-18 Farshad G. Veshki , Nora Ouzir , Sergiy A. Vorobyov , Esa Ollila

Analysis of brain imaging scans is critical to understanding the way the human brain functions, which can be leveraged to treat injuries and conditions that affect the quality of life for a significant portion of the human population. In…

Methodology · Statistics 2022-03-02 Daniel Spencer , David Bolin , Mary Beth Nebel , Amanda Mejia

All neuroimaging modalities have their own strengths and limitations. A current trend is toward interdisciplinary approaches that use multiple imaging methods to overcome limitations of each method in isolation. At the same time…

Methodology · Statistics 2023-03-30 Pratim Guha Niyogi , Martin A. Lindquist , Tapabrata Maiti

The main focus of image mining in the proposed method is concerned with the classification of brain tumor in the CT scan brain images. The major steps involved in the system are: pre-processing, feature extraction, association rule mining…

Computer Vision and Pattern Recognition · Computer Science 2010-03-25 P. Rajendran , M. Madheswaran

We propose an approach to better inform treatment decisions at an individual level by adapting recent advances in average treatment effect estimation to conditional average treatment effect estimation. Our work is based on doubly robust…

Methodology · Statistics 2023-06-13 Aaron Fisher , Virginia Fisher

Normative modelling is an increasingly common statistical technique in neuroimaging that estimates population-level benchmarks in brain structure. It enables the quantification of individual deviations from expected distributions whilst…

Neurons and Cognition · Quantitative Biology 2025-10-21 Nida Alyas , Jonathan Horsley , Bethany Little , Peter N. Taylor , Yujiang Wang , Karoline Leiberg

Traditional functional linear regression usually takes a one-dimensional functional predictor as input and estimates the continuous coefficient function. Modern applications often generate two-dimensional covariates, which become matrices…

Methodology · Statistics 2024-11-26 Dan Yang , Jianlong Shao , Haipeng Shen , Hongtu Zhu

The standard approach to the analysis of functional magnetic resonance imaging (FMRI) data applies various preprocessing steps to the original FMRI. These preprocessings lead to a general underestimation of residual variance in the…

Applications · Statistics 2018-09-20 Thomas Wilhelm Dieter Möbius

Resting-state brain functional connectivity quantifies the synchrony between activity patterns of different brain regions. In functional magnetic resonance imaging (fMRI), each region comprises a set of spatially contiguous voxels at which…

Methodology · Statistics 2025-11-07 Ruobin Liu , Chao Zhang , Chau Tran , Sophie Achard , Wendy Meiring , Alexander Petersen

Recent evidence has shown that structural magnetic resonance imaging (MRI) is an effective tool for Alzheimer's disease (AD) prediction and diagnosis. While traditional MRI-based diagnosis uses images acquired at a single time point, a…

Applications · Statistics 2021-11-02 Xiaowu Dai

Ultrasound, alone or in concert with circulating microbubble contrast agents, has emerged as a promising modality for therapy and imaging of brain diseases. While this has become possible due to advancements in aberration correction…

Signal Processing · Electrical Eng. & Systems 2020-01-08 Scott Schoen , Costas D. Arvanitis

In the common partially linear single-index model we establish a Bahadur representation for a smoothing spline estimator of all model parameters and use this result to prove the joint weak convergence of the estimator of the index link…

Statistics Theory · Mathematics 2024-07-03 Jiajun Tang , Holger Dette