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We construct uniform and point-wise asymptotic confidence sets for the single edge in an otherwise smooth image function which are based on rotated differences of two one-sided kernel estimators. Using methods from M-estimation, we show…

Statistics Theory · Mathematics 2019-03-26 Viktor Bengs , Matthias Eulert , Hajo Holzmann

Multivariate functional data has received considerable attention but testing for equality of mean surfaces and its profile has limited progress. The existing literature has tested equality of either mean curves of univariate functional…

Methodology · Statistics 2019-03-07 Jin Yang , Tao Zhang , Chunling Liu , Kam Chuen Yuen , Aiyi Liu

Parametric imaging of nuclear medicine data exploits dynamic functional images in order to reconstruct maps of kinetic parameters related to the metabolism of a specific tracer injected in the biological tissue. From a computational…

Numerical Analysis · Mathematics 2019-08-30 Serena Crisci , Michele Piana , Valeria Ruggiero , Mara Scussolini

Standard neuroimaging data analysis based on traditional principles of experimental design, modelling, and statistical inference is increasingly complemented by novel analysis methods, driven e.g. by machine learning methods. While these…

Neurons and Cognition · Quantitative Biology 2018-09-27 Kai Görgen , Martin N. Hebart , Carsten Allefeld , John-Dylan Haynes

Integrating brain imaging data with clinical reports offers a valuable opportunity to leverage complementary multimodal information for more effective and timely diagnosis in practical clinical settings. This approach has gained significant…

Computer Vision and Pattern Recognition · Computer Science 2025-08-12 Jing Zhang , Xiaowei Yu , Minheng Chen , Lu Zhang , Tong Chen , Yan Zhuang , Chao Cao , Yanjun Lyu , Li Su , Tianming Liu , Dajiang Zhu

Most brain disorders are very heterogeneous in terms of their underlying biology and developing analysis methods to model such heterogeneity is a major challenge. A promising approach is to use probabilistic regression methods to estimate…

Machine Learning · Statistics 2018-12-03 Seyed Mostafa Kia , Christian F. Beckmann , Andre F. Marquand

In some real world applications, such as spectrometry, functional models achieve better predictive performances if they work on the derivatives of order m of their inputs rather than on the original functions. As a consequence, the use of…

Statistics Theory · Mathematics 2011-05-04 Fabrice Rossi , Nathalie Villa-Vialaneix

An important goal of medical imaging is to be able to precisely detect patterns of disease specific to individual scans; however, this is challenged in brain imaging by the degree of heterogeneity of shape and appearance. Traditional…

This paper proposes and analyzes fully data driven methods for inference about the mean function of a stochastic process from a sample of independent trajectories of the process, observed at discrete time points and corrupted by additive…

Methodology · Statistics 2009-05-20 F. Bunea , M. H. Wegkamp , A. E. Ivanescu

Motivated by image-on-scalar regression with data aggregated across multiple sites, we consider a setting in which multiple independent studies each collect multiple dependent vector outcomes, with potential mean model parameter homogeneity…

Methodology · Statistics 2022-10-06 Emily C. Hector

Multimodal medical image fusion helps in combining contrasting features from two or more input imaging modalities to represent fused information in a single image. One of the pivotal clinical applications of medical image fusion is the…

Image and Video Processing · Electrical Eng. & Systems 2019-09-20 Nishant Kumar , Nico Hoffmann , Martin Oelschlägel , Edmund Koch , Matthias Kirsch , Stefan Gumhold

Image domain prior models have been shown to improve the quality of reconstructed images, especially when data are limited. Pre-processing of raw data, through the implicit or explicit inclusion of data domain priors have separately also…

Image and Video Processing · Electrical Eng. & Systems 2020-09-02 Muhammad Usman Ghani , W. Clem Karl

Functional data analysis finds widespread application across various fields. While functional data are intrinsically infinite-dimensional, in practice, they are observed only at a finite set of points, typically over a dense grid. As a…

Methodology · Statistics 2025-10-29 Ana Carolina da Cruz , Camila P. E. de Souza , Pedro H. T. O. Sousa

With rapid development of techniques to measure brain activity and structure, statistical methods for analyzing modern brain-imaging play an important role in the advancement of science. Imaging data that measure brain function are usually…

Methodology · Statistics 2023-01-05 Haoyi Fu , Lu Tang , Ori Rosen , Alison E. Hipwell , Theodore J. Huppert , Robert T. Krafty

In neuroscience, functional brain connectivity describes the connectivity between brain regions that share functional properties. Neuroscientists often characterize it by a time series of covariance matrices between functional measurements…

Methodology · Statistics 2019-07-09 Zhenhua Lin , Dehan Kong , Qiang Sun

The primary motivation and application in this article come from brain imaging studies on cognitive impairment in elderly subjects with brain disorders. We propose a regularized Haar wavelet-based approach for the analysis of…

Applications · Statistics 2014-08-11 Xuejing Wang , Bin Nan , Ji Zhu , Robert Koeppe

To detect differences between the mean curves of two samples in longitudinal study or functional data analysis, we usually need to partition the temporal or spatial domain into several pre-determined sub-areas. In this paper we apply the…

Methodology · Statistics 2015-05-01 Peirong Xu , Youngjo Lee , Jian Qing Shi

Current Computer-Aided Diagnosis (CAD) methods mainly depend on medical images. The clinical information, which usually needs to be considered in practical clinical diagnosis, has not been fully employed in CAD. In this paper, we propose a…

Image and Video Processing · Electrical Eng. & Systems 2021-03-11 Songxiao Yang , Xiabi Liu , Zhongshu Zheng , Wei Wang , Xiaohong Ma

In scientific disciplines such as neuroimaging, climatology, and cosmology it is useful to study the uncertainty of excursion sets of imaging data. While the case of imaging data obtained from a single study condition has already been…

Statistics Theory · Mathematics 2025-11-12 Thomas J. Maullin-Sapey , Fabian J. E. Telschow

We propose a fast bivariate smoothing approach for symmetric surfaces that has a wide range of applications. We show how it can be applied to estimate the covariance function in longitudinal data as well as multiple additive covariances in…

Computation · Statistics 2016-09-23 Jona Cederbaum , Fabian Scheipl , Sonja Greven