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Detecting arbitrarily shaped clusters in high-dimensional noisy data is challenging for current clustering methods. We introduce SHADE (Structure-preserving High-dimensional Analysis with Density-based Exploration), the first deep…
Clustering is a fundamental unsupervised learning approach. Many clustering algorithms -- such as $k$-means -- rely on the euclidean distance as a similarity measure, which is often not the most relevant metric for high dimensional data…
Identification of disease subtypes and corresponding biomarkers can substantially improve clinical diagnosis and treatment selection. Discovering these subtypes in noisy, high dimensional biomedical data is often impossible for humans and…
In this paper we develop a new unsupervised machine learning technique comprised of a feature extractor, a convolutional autoencoder (CAE), and a clustering algorithm consisting of a Bayesian Gaussian mixture model (BGM). We apply this…
As deep learning continues to advance, the transparency of neural network decision-making remains a critical challenge, limiting trust and applicability in high-stakes domains. Class Activation Mapping (CAM) techniques have emerged as a key…
Incorporating human domain knowledge for breast tumor diagnosis is challenging, since shape, boundary, curvature, intensity, or other common medical priors vary significantly across patients and cannot be employed. This work proposes a new…
Auto-Encoder (AE)-based deep subspace clustering (DSC) methods have achieved impressive performance due to the powerful representation extracted using deep neural networks while prioritizing categorical separability. However,…
Deep multi-view subspace clustering (DMVSC) has recently attracted increasing attention due to its promising performance. However, existing DMVSC methods still have two issues: (1) they mainly focus on using autoencoders to nonlinearly…
Unsupervised clustering has broad applications in data stratification, pattern investigation and new discovery beyond existing knowledge. In particular, clustering of bioactive molecules facilitates chemical space mapping,…
Traditional image clustering methods take a two-step approach, feature learning and clustering, sequentially. However, recent research results demonstrated that combining the separated phases in a unified framework and training them jointly…
Pulmonary emphysema is traditionally subcategorized into three subtypes, which have distinct radiological appearances on computed tomography (CT) and can help with the diagnosis of chronic obstructive pulmonary disease (COPD). Automated…
Localization of chest pathologies in chest X-ray images is a challenging task because of their varying sizes and appearances. We propose a novel weakly supervised method to localize chest pathologies using class aware deep multiscale…
Patch classification models based on deep learning have been utilized in whole-slide images (WSI) of H&E-stained tissue samples to assist pathologists in grading follicular lymphoma patients. However, these approaches still require…
Feature selection is an essential problem in computer vision, important for category learning and recognition. Along with the rapid development of a wide variety of visual features and classifiers, there is a growing need for efficient…
Clustering is an essential problem in machine learning and data mining. One vital factor that impacts clustering performance is how to learn or design the data representation (or features). Fortunately, recent advances in deep learning can…
Feature selection methods are widely used to address the high computational overheads and curse of dimensionality in classifying high-dimensional data. Most conventional feature selection methods focus on handling homogeneous features,…
Face clustering is an essential tool for exploiting the unlabeled face data, and has a wide range of applications including face annotation and retrieval. Recent works show that supervised clustering can result in noticeable performance…
In this paper, we present contemporary techniques for visualising the feature space of a deep learning image classification neural network. These techniques are viewed in the context of a feed-forward network trained to classify low…
Image clustering is a very useful technique that is widely applied to various areas, including remote sensing. Recently, visual representations by self-supervised learning have greatly improved the performance of image clustering. To…
Due to the wider availability of modern electronic health records, patient care data is often being stored in the form of time-series. Clustering such time-series data is crucial for patient phenotyping, anticipating patients' prognoses by…